Atlas of Cardiac Innervation

1. Front Matter

   Pages i-x

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2. Anatomy and Molecular Basis of Autonomic Innervation of the Heart

   • Wengen Chen, Vasken Dilsizian

   Pages 1-12

3. Neural Control of Cardiac Function in Health and Disease

   • Pradeep S. Rajendran, Ray W. Chui, Olujimi A. Ajijola, Marmar Vaseghi, J. Andrew Armour, Jeffrey L. Ardell et al.

   Pages 13-35

4. Chemistry and Biology of Radiotracers Designed to Target Changes in the Myocardial Sympathetic and Parasympathetic Nervous Systems as a Function of Disease or Treatment

   • William C. Eckelman, Vasken Dilsizian

   Pages 37-46

5. Neuronal Imaging in Heart Failure

   • Arnold F. Jacobson, Jagat Narula

   Pages 47-70

6. PET Imaging and Quantitation of Cardiac Innervation

   • Stanley F. Fernandez, John M. Canty Jr, James A. Fallavollita

   Pages 71-82

7. Neuronal Imaging and Reverse Remodeling

   • Wataru Fujita, Kouji Kajinami, Ichiro Matsunari

   Pages 83-102

8. Neuronal Imaging, Ventricular Arrhythmias, and Device Therapy in Heart Failure

   • David M. Harris, Myron C. Gerson

   Pages 103-129

9. Cardiac Sympathetic Innervation and Ablation of Ventricular Tachycardia

   • John T. Duell, Thomas Klein, Mark F. Smith, Wengen Chen, Vasken Dilsizian, Timm Dickfeld

   Pages 131-145

10. Dysautonomia: From the Brain Disorders to Neuropathies and Including Diabetes

    • Albert Flotats, Ignasi Carrió

    Pages 147-167

11. Cardiac Transplantation: Denervation, Reinnervation, and Myocardial Blood Flow

    • Avishay Grupper, Henry Gewirtz, Sudhir S. Kushwaha

    Pages 169-179

12. Back Matter

    Pages 181-183

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This atlas elucidates the role of the neuronal component in normal cardiovascular function and cardiac disorders and discusses the currently available imaging targets and probes. It provides a foundation in cardiac neuronal imaging and image processing and serves as a guide in the effective utilization of these techniques in clinical and research settings. The atlas discusses the principles of autonomic control in the regulation of cardiac function and disease; chemistry and biology of radiotracers designed to target changes in the myocardial sympathetic and parasympathetic innervation as a function of disease or treatment; neuronal imaging in heart failure and reverse remodeling and the use of PET imaging in quantification of cardiac innervation; cardiac sympathetic innervation in ventricular arrhythmias and device therapy; conditions that affect the autonomic nervous system; and the role of myocardial blood flow and cardiac neuronal imaging in denervation and reinnervation in cardiactransplant recipients. Featuring full-color illustrations, schematic diagrams, and diagnostic algorithms, Atlas of Cardiac Innervation is a valuable resource for cardiologists, radiologists, nuclear medicine physicians, and electrophysiologists.

• autonomic nervous system
• cardiac innervation
• cardiology
• heart failure
• imaging agents
• left ventricular dysfunction
• Diagnostic Radiology

• Division of Nuclear Medicine Department of Diagnostic Radiology, University of Maryland School of Medicine, Baltimore, USA

  Vasken Dilsizian

• Division of Cardiology, Mount Sinai Medical Center, New York, USA

  Jagat Narula

Vasken Dilsizian, MD, University of Maryland School of Medicine, Baltimore, MD, USA 

Jagat Narula, MD, PhD, Mount Sinai Medical Center, New York, NY, USA 

Drs. Dilsizian and Narula are the editors of Atlas of Nuclear Cardiology, 4th ed (2013)

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