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Bacteriophage Applications - Historical Perspective and Future Potential

  • Book
  • © 2016

Overview

Authors:
  1. Jessica Nicastro

    1. School of Pharmacy, University of Waterloo, Waterloo, Canada

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  2. Shirley Wong

    1. School of Pharmacy, University of Waterloo, Waterloo, Canada

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  3. Zahra Khazaei

    1. Western University , London, Canada

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  4. Peggy Lam

    1. University of Waterloo , Waterloo, Canada

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  5. Jonathan Blay

    1. School of Pharmacy, University of Waterloo, Waterloo, Canada

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  6. Roderick A. Slavcev

    1. University of Waterloo, School of Pharmacy University of Waterloo, Waterloo, Canada

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  • Explores key applications of phage biotechnology
  • Reviews recent advances in phage display technologies
  • Discusses the significance and role of phage recombination systems
  • Includes supplementary material: sn.pub/extras

Part of the book series: SpringerBriefs in Biochemistry and Molecular Biology (BRIEFSBIOCHEM)

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Table of contents (7 chapters)

  1. Front Matter

    Pages i-vii
    Download chapter PDF

  2. Overview of Bacteriophage Lifecycles and Applications

    • Jessica Nicastro
    Pages 1-8

  3. Phage for Biocontrol

    • Jessica Nicastro, Zahra Khazaei, Jonathan Blay
    Pages 9-19

  4. Phage Device Coatings

    • Jessica Nicastro, Peggy Lam, Jonathan Blay
    Pages 21-28

  5. Bacteriophages Functionalized for Gene Delivery and the Targeting of Gene Networks

    • Jessica Nicastro, Shirley Wong, Roderick A. Slavcev
    Pages 29-38

  6. Phage Probiotics

    • Shirley Wong
    Pages 39-58

  7. Phage for Biodetection

    • Jessica Nicastro, Roderick A. Slavcev
    Pages 59-67

  8. Phage-Mediated Immunomodulation

    • Jessica Nicastro, Shirley Wong, Roderick A. Slavcev
    Pages 69-82
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Keywords

About this book

This book explores key applications of phage biotechnology and reviews recent advances in phage display technologies. The applications covered were selected on the basis of their significance and representativeness in the field.

The small size and enormous diversity of bacteriophages make them ideal candidates for numerous applications across many industries. Since the discovery of phages and the advent of phage display systems, considerable attention has been focused on the development of novel therapeutic and industrial applications. Recent studies combine the genomic flexibility of phages with phage display systems in order to generate modified phages for targeted delivery.

Authors and Affiliations

  • School of Pharmacy, University of Waterloo, Waterloo, Canada

    Jessica Nicastro, Shirley Wong, Jonathan Blay

  • Western University , London, Canada

    Zahra Khazaei

  • University of Waterloo , Waterloo, Canada

    Peggy Lam

  • University of Waterloo, School of Pharmacy University of Waterloo, Waterloo, Canada

    Roderick A. Slavcev

About the authors

Roderick A. Slavcev, PhD, MBA, MRSB, CBiol.
Associate Professor, Pharmaceutical Sciences 
Professor of Business and Entrepreneurship
School of Pharmacy, University of Waterloo
President, Mediphage Bioceuticals, Inc.


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