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Strategies to Enhance the Therapeutic Ratio of Radiation as a Cancer Treatment

  • Book
  • © 2016

Overview

Editors:
  1. Mitchell S. Anscher

    1. Department of Radiation Oncology Massey Cancer Center, Virginia Commonwealth University, Richmond, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Kristoffer Valerie

    1. Department of Radiation Oncology Massey Cancer Center, Virginia Commonwealth University, Richmond, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Describes the recent progress and future directions in radiation oncology and biology research

  • Focuses on strategies designed to improve disease control and reduce the risk of long-term adverse effects on patients

  • Enables practitioners to understand an increasingly important strategy in radiation oncology and throughout the field of oncology

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-vi
    Download chapter PDF

  2. Mechanisms of Normal Tissue Response

    • Jolinta Y. Lin, Isabel L. Jackson, Zeljko Vujaskovic
    Pages 1-28

  3. The Role of Hypoxia in Radiation Response

    • Monica M. Olcina, Ryan Kim, Amato J. Giaccia
    Pages 29-42

  4. The Role of Cancer Stem Cells in Tumour Radioresponse

    • Annett Linge, Anna Dubrovska, Michael Baumann, Mechthild Krause
    Pages 43-74

  5. Novel Strategies to Prevent, Mitigate or Reverse Radiation Injury and Fibrosis

    • Pierre Montay-Gruel, Gael Boivin, Marie-Catherine Vozenin
    Pages 75-108

  6. Technology Based Strategies to Enhance the Therapeutic Ratio

    • David V. Fried, Shiva K. Das
    Pages 109-138

  7. Nitric Oxide Synthase Uncoupling in Tumor Progression and Cancer Therapy

    • Ross B. Mikkelsen, Vasily A. Yakovlev, Christopher S. Rabender, Asim Alam
    Pages 139-158

  8. Aiming the Immune System to Improve the Antitumor Efficacy of Radiation Therapy

    • Chunqing Guo, Timothy Harris, Xiang-Yang Wang
    Pages 159-181

  9. The Role of MicroRNAs in Modulating Tissue Response to Radiation

    • Rebecca J. Boohaker, Bo Xu
    Pages 183-193

  10. Adapting Therapy Based on Tumor Response

    • Christina Hunter Chapman, Yue Cao, Martha Matuszak, Matt Schipper, Theodore S. Lawrence
    Pages 195-224

  11. NQO1 Bioactivatable Drugs Enhance Radiation Responses

    • Erik A. Bey, Julia C. Meade, Molly A. Silvers, Edward A. Motea, Praveen L. Patidar, Rolf Brekken et al.
    Pages 225-252

  12. DNA Repair Pathways as a Potential Target for Radiosensitization

    • Mahmoud Toulany
    Pages 253-287

  13. Radiosensitizing Glioma by Targeting ATM with Small Molecule Inhibitors

    • Amrita Sule, Kristoffer Valerie
    Pages 289-305
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Keywords

About this book


This volume will describe recent progress and future directions in radiation oncology and biology research, focusing on strategies designed to improve disease control and reduce the risk of long-term adverse effects on patients. As more and more patients are becoming long-term survivors, this strategy will become increasingly important--in radiation oncology and throughout the field of oncology.

Editors and Affiliations

  • Department of Radiation Oncology Massey Cancer Center, Virginia Commonwealth University, Richmond, USA

    Mitchell S. Anscher, Kristoffer Valerie

About the editors

Mitchell S. Anscher, MD, FACR, FACRO, FASTRO, is Professor, Department of Radiation Oncology, Virginia Commonwealth University School of Medicine.Kristoffer Valerie, PhD, is Professor, Division of Molecular Radiobiology, Department of Radiation Oncology, Co-Leader, Radiation Biology & Oncology Program, Massey Cancer Center, Virginia Commonwealth University. 

Bibliographic Information

  • Book Title: Strategies to Enhance the Therapeutic Ratio of Radiation as a Cancer Treatment

  • Editors: Mitchell S. Anscher, Kristoffer Valerie

  • DOI: https://doi.org/10.1007/978-3-319-45594-5

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing Switzerland 2016

  • Hardcover ISBN: 978-3-319-45592-1Published: 03 November 2016

  • Softcover ISBN: 978-3-319-83326-2Published: 05 July 2018

  • eBook ISBN: 978-3-319-45594-5Published: 20 October 2016

  • Edition Number: 1

  • Number of Pages: VI, 305

  • Number of Illustrations: 12 b/w illustrations, 53 illustrations in colour

  • Topics: Cancer Research

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