Editors:
- Outlines how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo
- Aids in understanding many aspects of the enhanced study of tumor cell biology in a physiologic context
- Opens new avenues for drug screening and biomarker development
- Accelerates the preclinical evaluation of novel personalized medicine strategies for patients in real time
- Includes supplementary material: sn.pub/extras
Part of the book series: Cancer Drug Discovery and Development (CDD&D)
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Table of contents (7 chapters)
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Front Matter
About this book
This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in understanding many aspects of the enhanced study of tumor cell biology in a physiologic context, open new avenues for drug screening and biomarker development, and accelerate the preclinical evaluation of novel personalized medicine strategies for patients in real time.
Editors and Affiliations
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Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA
Amir R. Aref, David Barbie
About the editors
Bibliographic Information
Book Title: Ex Vivo Engineering of the Tumor Microenvironment
Editors: Amir R. Aref, David Barbie
Series Title: Cancer Drug Discovery and Development
DOI: https://doi.org/10.1007/978-3-319-45397-2
Publisher: Humana Cham
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer International Publishing Switzerland 2017
Hardcover ISBN: 978-3-319-45395-8Published: 16 December 2016
Softcover ISBN: 978-3-319-83282-1Published: 30 April 2018
eBook ISBN: 978-3-319-45397-2Published: 09 December 2016
Series ISSN: 2196-9906
Series E-ISSN: 2196-9914
Edition Number: 1
Number of Pages: IX, 135
Number of Illustrations: 1 b/w illustrations, 17 illustrations in colour
Topics: Cancer Research