Overview
- Extensive coverage of the role of AMPK as master regulator of cell energy levels in disease and aging
- Presents new methods and animal models for the study of this enzyme
- Includes effects of drugs and nutraceutical compounds
Part of the book series: Experientia Supplementum (EXS, volume 107)
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Table of contents (21 chapters)
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Front Matter
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AMPK in Health
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Front Matter
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Pharmacology of AMPK
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Front Matter
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AMPK Non-mammalian Systems
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Front Matter
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Keywords
About this book
AMPK has emerged as an important integrator of signals that control energy balance through the regulation of multiple biochemical pathways in eukaryotes.
This book focuses on the implications of AMPK as a master metabolic regulator in diseases, including new methods and animal models. The contributions are written by leading experts in the field and give an extensive overview of the current knowledge of AMPK biology and the role of AMPK in health and disease.
Editors and Affiliations
About the editors
Mario D Cordero is Research Associate at the University of Sevilla, Laboratory of Biological Research. He studies the role of AMPK in the metabolic abnormalities of the central nervous system in psychiatric diseases, and the implication of AMPK in the mechanism of pain and inflammation. He is also involved in drug trials using AMPK activators in rare diseases.
Benoit Viollet leads a research team at the Institut Cochin, Paris, which studies the physiological role of AMPK in cellular energy balance and the integrated stress response such as exercise, as well as nutrient and hormonal signals. The work includes studies of the therapeutic opportunity of AMPK in metabolic abnormalities associated with type 2 diabetes and obesity.
Bibliographic Information
Book Title: AMP-activated Protein Kinase
Editors: Mario D. Cordero, Benoit Viollet
Series Title: Experientia Supplementum
DOI: https://doi.org/10.1007/978-3-319-43589-3
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing Switzerland 2016
Hardcover ISBN: 978-3-319-43587-9Published: 28 November 2016
Softcover ISBN: 978-3-319-82864-0Published: 28 June 2018
eBook ISBN: 978-3-319-43589-3Published: 02 November 2016
Series ISSN: 1664-431X
Series E-ISSN: 2504-3692
Edition Number: 1
Number of Pages: X, 523
Number of Illustrations: 13 b/w illustrations, 42 illustrations in colour
Topics: Human Physiology, Medical Biochemistry, Metabolic Diseases