Overview
- Editors:
-
-
Seunghee Cha
-
Oral and Maxillofacial Diagnostic Sciences, University of Florida, Gainesville, USA
- Offers a comprehensive update on latest knowledge in the field
- Discusses stem cell replacement therapy in depth
- Examines the latest advances in bioengineering
Access this book
Other ways to access
Table of contents (13 chapters)
-
Front Matter
Pages i-xiii
-
Updates on Salivary Gland Development
-
-
-
- Melinda Larsen, Petko Bogdanov, Ravi Sood, Hae Ryong Kwon, Deirdre A. Nelson, Connor Duffy et al.
Pages 23-44
-
- Isabel Castro, María-José Barrera, Sergio González, Sergio Aguilera, Ulises Urzúa, Juan Cortés et al.
Pages 45-71
-
Glandular Damage and Cell Replacement Therapy
-
-
-
- Simon D Tran, Yoshinori Sumita, Dongdong Fang, Shen Hu
Pages 93-102
-
- Yun-Jong Park, Seunghee Cha
Pages 103-129
-
Bioengineering of Salivary Glands
-
Front Matter
Pages 131-131
-
-
- Mariane Martinez, Danielle Wu, Mary C. Farach-Carson, Daniel A. Harrington
Pages 145-171
-
- Jong Woo Choi, Namkug Kim, Chang Mo Hwang
Pages 173-191
-
- Miho Ogawa, Takashi Tsuji
Pages 193-203
-
Therapeutic Considerations for Restoration of Salivary Function
-
Front Matter
Pages 205-205
-
- Guy Carpenter, Polliane Carvalho
Pages 207-215
-
-
- Varun V. Varadarajan, Peter T. Dziegielewski
Pages 229-263
About this book
This book provides a comprehensive update on the latest information and knowledge which emerged from translational and basic science research endeavors, targeting the regeneration of salivary glands. The coverage includes salivary gland growth and development, stem cell therapy, bioengineering of salivary glands, and perspectives on and practical approaches to restoration of secretory function. More specifically, among the individual topics addressed are the various types of stem cell of value for cell replacement therapy, technological advances with respect to 3D printing, gene therapy, organ culture of salivary glands, and surgical aspects of the feasibility and practicality of transplantation. Readers will find helpful practical guidance on functional restorations of damaged salivary glands and stimulating insights into potential future directions in salivary gland regeneration research. The authors are all acknowledged experts from a range of academic and clinical backgrounds.Accordingly, the book will be of interest not only to clinicians, such as general dental practitioners, oral medicine specialists, and surgeons who manage dry mouth patients, but also to biomedical engineers, stem cell researchers, and transplant surgeons.
Editors and Affiliations
-
Oral and Maxillofacial Diagnostic Sciences, University of Florida, Gainesville, USA
Seunghee Cha
About the editor
Seunghee Cha, DDS, PhD, is an Associate Professor in the Section of Oral Medicine and Joint Associate Professor in Oral Biology, Department of Oral and Maxillofacial Diagnostic Sciences, University of Florida College of Dentistry. Dr. Cha is actively involved in basic and clinical science research while serving leadership roles in various international scientific communities. Her main research interests include the pathogenesis of autoimmune Sjӧgren’s syndrome (SjS) and cell replacement therapy for dry mouth. Her current and future studies are focusing on the pathological roles of anti-M3R autoantibodies in SjS hyposalivation, the pro-inflammatory microenvironment in the salivary glands for target tissue specificity, microRNA expression and its functions in innate immunity of SjS, identification of susceptibility genes by application of functional genomics and proteomics, application of receptor-mediated siRNA delivery in SjS, and development of preventive and therapeutic strategies for dry mouth. Dr. Cha has published extensively in peer-reviewed international journals.