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Cardiac Biomarkers

Case Studies and Clinical Correlations

  • Book
  • © 2016

Overview

Editors:
  1. Alan S. Maisel

    1. Division of Cardiovascular Medicine, University of California San Diego Division of Cardiovascular Medicine, La Jolla, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Allan S. Jaffe

    1. Cardiology Department, Mayo Clinic Cardiology Department, ROCHESTER, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Contains clinical cases detailing the uses of biomarkers to define outcomes

  • Takes a teaching file approach to establish best practice

  • Presents clinical information in a practical manner and includes a wealth of algorithms and explanatory illustrations?

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Table of contents (28 chapters)

  1. Front Matter

    Pages i-xviii
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  2. Ischemic Heart Disease

    1. Front Matter

      Pages 1-1
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    2. Pre-analytical Factors and Analytical Issues Affecting Interpretation of Cardiovascular Biomarkers

      • Amy K. Saenger
      Pages 3-15

    3. Troponin Basics for Clinicians

      • Yader Sandoval, Fred S. Apple
      Pages 17-29

    4. Unique Aspects of High Sensitivity Assays: What Are They, Why Do We Need Them, and How Do We Use Them?

      • Paul Ormandy Collinson
      Pages 31-39

    5. Evaluation of Patients Presenting with Chest Pain in the Emergency Department: Where Do Troponins Fit In?

      • Martin Paul Than, Louise Cullen
      Pages 41-55

    6. Using Cardiac Troponins in Patients with Acute Myocardial Infarction

      • Johannes Mair, Kristian Thygesen
      Pages 57-68

    7. What Is a Type 2 Myocardial Infarction: How Is It Recognized and What Should One Do to Establish That Diagnosis?

      • Joseph S. Alpert, Allan S. Jaffe
      Pages 69-78

    8. Use of Cardiac Troponin in Patients with Heart Failure

      • Wayne L. Miller
      Pages 79-91

    9. Elevated cTn in Other Acute Situations Such as Atrial Fibrillation, Sepsis, Respiratory Failure, and Gastrointestinal Bleeding

      • Evangelos Giannitsis, Hugo A. Katus
      Pages 93-109

    10. Use of cTn for Detection of More Chronic Disease States

      • Ravi H. Parikh, Christopher R. deFilippi
      Pages 111-122

    11. Use of High-Sensitive cTn Assays for the Evaluation of Patients Potentially at Risk for Cardiovascular Disease

      • Kai M. Eggers, Per Venge
      Pages 123-134

    12. Other Biomarkers in Acute Coronary Syndrome

      • Roxana Ghashghaei, Nicholas Marston
      Pages 135-143

    13. Newer Lipid Markers: Apolipoprotein B, LDL Particle Concentration, and Triglyceride-Rich Lipoproteins – When Are They Needed?

      • Renato Quispe, Seth S. Martin, Steven R. Jones
      Pages 145-158

  3. Heart Failure

    1. Front Matter

      Pages 159-159
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    2. Natriuretic Peptides: Physiology for the Clinician

      • Siu-Hin Wan, Horng H. Chen
      Pages 161-172

    3. Natriuretic Peptides: Basic Analytic Considerations

      • Alan H. B. Wu
      Pages 173-180

    4. Natriuretic Peptide Use in Screening in the Community

      • Noel S. Lee, Lori B. Daniels
      Pages 181-193

    5. Natriuretic Peptide Use in the Emergency Department

      • W. Frank Peacock, Salvator DiSomma
      Pages 195-206

    6. Heart Failure: Natriuretic Peptide Use in the Hospital

      • Kevin Shah, James Iwaz
      Pages 207-213
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Keywords

About this book

This book covers ACS and Heart Failure, the chapters represent the most current, up to date and knowledgeable content on the topic available. It is written by the worlds most respected leaders in biomarkers, with a majority emphasis on what clinicians need to know.
The Editors and their contributors have provided algorithms, annotated case discussions and caveats. They cover biomarkers to predict risk of heart disease, biomarkers of cardiorenal disease , and conclude with a section on new and emerging biomarkers. It be genuinely helpful and practical to those in the field, including not just people working in the field, but nurses, doctors, etc who practice medicine in the clinic, the emergency department and the hospital.​

Reviews

“The purpose is to remind readers of the strengths and weaknesses inherent in the specific markers in commonly used cardiac laboratory tests. … The book accomplishes this by reminding providers of the nuances specific to each test and incorporating these in real clinical cases. This book is intended for any provider -- resident, attending, or midlevel -- who orders or interprets cardiac biomarkers. … book would be of most benefit to those working in cardiology as opposed to broader fields.” (Merrill H. Stewart, Doody's Book Reviews, February, 2017)

Editors and Affiliations

  • Division of Cardiovascular Medicine, University of California San Diego Division of Cardiovascular Medicine, La Jolla, USA

    Alan S. Maisel

  • Cardiology Department, Mayo Clinic Cardiology Department, ROCHESTER, USA

    Allan S. Jaffe

About the editors

Alan S. Maisel is a Professor of Medicine at the University of California, San Diego (UCSD). He is the Director of the Coronary Care Unit and Heart Failure Program at the VA San Diego Healthcare System in La Jolla, California. Dr. Maisel is active on the faculty at UCSD where he has won numerous teaching awards. Dr Maisel is considered one of the world’s experts on cardiac biomarkers and has over 300 scientific publications. He has authored several ground-breaking publications that have paved the way for development of diagnostic tools for patients with congestive heart failure. In particular, he was the leading investigator on studies that brought the use of BNP into clinical practice. Dr Maisel is also a writer of medical fiction. His first novel, Bedside Manners was optioned to Warner Brothers. His second novel, Brain Chicane, is about a young and idealistic physician working at the premier multiple-organ transplant hospital in Chicago where he investigates overdose cases that are not totally kosher. 

Allan Jaffe is Professor of Medicine and Professor of Laboratory Medicine and Pathology and Chair of the Division of Core Clinical Laboratory Services at Mayo. He continues as an active clinician in the CCU. Dr. Jaffe has national and international repute for his work in cardiac biomarkers and co-ordinates the Biochemistry group of the taskforce for the Universal Definition of AMI. He is on the editor boards of most of the major cardiology journals and the most prestigious laboratory medicine one (Clinical Chemistry) as well. He has over 500 publications, mostly in the field of biomarkers and cardiac troponin.

Bibliographic Information

  • Book Title: Cardiac Biomarkers

  • Book Subtitle: Case Studies and Clinical Correlations

  • Editors: Alan S. Maisel, Allan S. Jaffe

  • DOI: https://doi.org/10.1007/978-3-319-42982-3

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing Switzerland 2016

  • Softcover ISBN: 978-3-319-42980-9Published: 02 November 2016

  • eBook ISBN: 978-3-319-42982-3Published: 24 October 2016

  • Edition Number: 1

  • Number of Pages: XVIII, 370

  • Number of Illustrations: 16 b/w illustrations, 40 illustrations in colour

  • Topics: Cardiology

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