Circulating Nucleic Acids in Serum and Plasma – CNAPS IX

1. Front Matter

   Pages i-xxii

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2. Nucleic Acids in Oncology – Prognosis, Treatments Screening and Metastases

   1. Front Matter

      Pages 1-1

      PDF

   2. Circulating Cell-Free miR-373, miR-200a, miR-200b and miR-200c in Patients with Epithelial Ovarian Cancer

      • Xiaodan Meng, Volkmar Müller, Karin Milde-Langosch, Fabian Trillsch, Klaus Pantel, Heidi Schwarzenbach

      Pages 3-8

   3. Cell-Free miRNA-141 and miRNA-205 as Prostate Cancer Biomarkers

      • Ivan D. Osipov, Ivan A. Zaporozhchenko, Anna A. Bondar, Marat M. Zaripov, Vladimir E. Voytsitskiy, Valentin V. Vlassov et al.

      Pages 9-12

   4. Clinical Utility of Circulating Tumor DNA for Molecular Assessment and Precision Medicine in Pancreatic Cancer

      • Erina Takai, Yasushi Totoki, Hiromi Nakamura, Mamoru Kato, Tatsuhiro Shibata, Shinichi Yachida

      Pages 13-17

   5. An Enquiry Concerning the Characteristics of Cell-Free DNA Released by Cultured Cancer Cells

      • Abel Jacobus Bronkhorst, Johannes F. Wentzel, Janine Aucamp, Etresia van Dyk, Lissinda H. du Plessis, Piet J. Pretorius

      Pages 19-24

   6. Detection of p53 Mutations in Circulating DNA of Transplanted Hepatocellular Carcinoma Patients as a Biomarker of Tumor Recurrence

      • N. García-Fernández, Hada C. Macher, Amalia Rubio, Pilar Jiménez-Arriscado, C. Bernal-Bellido, M. L. Bellido-Díaz et al.

      Pages 25-28

   7. Unbiased Detection of Somatic Copy Number Aberrations in cfDNA of Lung Cancer Cases and High-Risk Controls with Low Coverage Whole Genome Sequencing

      • Fiona Taylor, James Bradford, Penella J. Woll, Dawn Teare, Angela Cox

      Pages 29-32

   8. Liquid Profiling in Lung Cancer – Quantification of Extracellular miRNAs in Bronchial Lavage

      • Bernd Schmidt, Grit Rehbein, Michael Fleischhacker

      Pages 33-37

   9. Screening of KRAS Mutation in Pre- and Post-Surgery Serum of Patients Suffering from Colon Cancer by COLD-PCR HRM

      • Elena Trujillo-Arribas, Hada C. Macher, Pilar Jiménez-Arriscado, Fernando de la Portilla, Patrocinio Molinero, Juan M. Guerrero et al.

      Pages 39-41

   10. Non-dividing Cell Virtosomes Affect In Vitro and In Vivo Tumour Cell Replication

       • Mariano Garcia-Arranz, Damian Garcia-Olmo, Luz Vega-Clemente, Maurice Stroun, Peter B. Gahan

       Pages 43-45

   11. Features of Circulating DNA Fragmentation in Blood of Healthy Females and Breast Cancer Patients

       • Svetlana N. Tamkovich, Natalia A. Kirushina, Vladimir E. Voytsitskiy, Vsevolod A. Tkachuk, Pavel P. Laktionov

       Pages 47-51

   12. Liquid Profiling of Circulating Nucleic Acids as a Novel Tool for the Management of Cancer Patients

       • Stefan Holdenrieder

       Pages 53-60

3. CNAPS in Foetal Medicine

   1. Front Matter

      Pages 61-61

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   2. Characterization of Human Pregnancy Specific Glycoprotein (PSG) Gene Copy Number Variations in Pre-eclampsia Patients

      • Chia Lin Chang, Chia Yu Chang, Da Xian Lee, Po Jen Cheng

      Pages 63-65

   3. Non-invasive Prenatal Diagnosis of Feto-Maternal Platelet Incompatibility by Cold High Resolution Melting Analysis

      • Marta Ferro, Hada C. Macher, Pilar Noguerol, Pilar Jimenez-Arriscado, Patrocinio Molinero, Juan M. Guerrero et al.

      Pages 67-70

   4. Implementing Non-Invasive Prenatal Diagnosis (NIPD) in a National Health Service Laboratory; From Dominant to Recessive Disorders

      • Suzanne Drury, Sarah Mason, Fiona McKay, Kitty Lo, Christopher Boustred, Lucy Jenkins et al.

      Pages 71-75

4. Biology of CNAPS

   1. Front Matter

      Pages 77-77

      PDF

   2. Comparative Analysis of Harmful Physical Factors Effect on the Cell Genome

      • Irina N. Vasilyeva, Valery N. Zinkin, Vladimir G. Bespalov

      Pages 79-84

   3. Heterochromatic Tandem Repeats in the Extracellular DNA

      • Olga I. Podgornaya, Irina N. Vasilyeva, Vladimir G. Bespalov

      Pages 85-89

The book will present the progress made since the last meeting in fall 2013 concerning the analysis of circulating extra-cellular nucleic acids. There are a modest number of laboratories involved in this field, nevertheless the number of papers published by researchers is extensive. The articles which will be published in this meeting report will be a valuable contribution for researchers and research students alike and will help them to stay on top of the developments in different research areas and to „cross borders“ between them.

• Cancer Research
• analysis of circulating fetal nucleic acids in pregnant women
• biological bases of extracellular nucleic acids
• functions of extracellular nucleic acids
• non-malignant disease
• microarrays

• ICRM, Inserm, Montpellier Cedex, France

  Peter B. Gahan

• Universitätsklinikum Halle (Saale), Klinik für Innere Medizin, Schwerpunkt Pneumologie, Halle/Saale, Germany

  Michael Fleischhacker, Bernd Schmidt

Policies and ethics