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  • Book
  • © 2016

Management of Soft Tissue Sarcoma

  • Written by world renowned experts

  • Includes up-to-date data since last edition and an expanded chapter on radiation therapy

  • Only book where specific recommendations on chemotherapy as a function of specific subtypes are discussed

  • Covers surgical treatment, chemotherapy, radiation therapy, and novel pharmacotherapy

  • Gives a practical, up-to-date approach to all the different subtypes of adult soft tissue sarcoma

  • Includes supplementary material: sn.pub/extras

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Table of contents (27 chapters)

  1. Front Matter

    Pages i-xvi
  2. Introduction

    1. Front Matter

      Pages 1-1
    2. General Description

      • Murray F. Brennan, Cristina R. Antonescu, Kaled M. Alektiar, Robert G. Maki
      Pages 3-17
    3. Natural History: Importance of Size, Site, Histopathology

      • Murray F. Brennan, Cristina R. Antonescu, Kaled M. Alektiar, Robert G. Maki
      Pages 19-40
    4. General Statement as to Efficacy of Surgery, Chemotherapy, Radiation Therapy, and Immunotherapy

      • Murray F. Brennan, Cristina R. Antonescu, Kaled M. Alektiar, Robert G. Maki
      Pages 41-74
  3. Management by Histopathology

    1. Front Matter

      Pages 75-75
    2. Gastrointestinal Stromal Tumors

      • Murray F. Brennan, Cristina R. Antonescu, Kaled M. Alektiar, Robert G. Maki
      Pages 77-104
    3. Liposarcoma

      • Murray F. Brennan, Cristina R. Antonescu, Kaled M. Alektiar, Robert G. Maki
      Pages 105-124
    4. Leiomyosarcoma

      • Murray F. Brennan, Cristina R. Antonescu, Kaled M. Alektiar, Robert G. Maki
      Pages 125-142
    5. Undifferentiated Pleomorphic Sarcoma (UPS) (Malignant Fibrous Histiocytoma (MFH) and Myxofibrosarcoma)

      • Murray F. Brennan, Cristina R. Antonescu, Kaled M. Alektiar, Robert G. Maki
      Pages 143-152
    6. Synovial Sarcoma

      • Murray F. Brennan, Cristina R. Antonescu, Kaled M. Alektiar, Robert G. Maki
      Pages 153-163
    7. Malignant Peripheral Nerve Sheath Tumor (MPNST) and Triton Tumor

      • Murray F. Brennan, Cristina R. Antonescu, Kaled M. Alektiar, Robert G. Maki
      Pages 165-176
    8. Desmoid Tumor/Deep-Seated Fibromatosis (Desmoid-Type Fibromatosis)

      • Murray F. Brennan, Cristina R. Antonescu, Kaled M. Alektiar, Robert G. Maki
      Pages 177-194
    9. Solitary Fibrous Tumor/Hemangiopericytoma

      • Murray F. Brennan, Cristina R. Antonescu, Kaled M. Alektiar, Robert G. Maki
      Pages 195-201
    10. Fibrosarcoma and Its Variants

      • Murray F. Brennan, Cristina R. Antonescu, Kaled M. Alektiar, Robert G. Maki
      Pages 203-219
    11. Vascular Sarcomas

      • Murray F. Brennan, Cristina R. Antonescu, Kaled M. Alektiar, Robert G. Maki
      Pages 221-236
    12. Epithelioid Sarcoma

      • Murray F. Brennan, Cristina R. Antonescu, Kaled M. Alektiar, Robert G. Maki
      Pages 237-241
    13. Sarcomas More Common in Children

      • Murray F. Brennan, Cristina R. Antonescu, Kaled M. Alektiar, Robert G. Maki
      Pages 243-274
    14. Radiation-Induced Sarcoma

      • Murray F. Brennan, Cristina R. Antonescu, Kaled M. Alektiar, Robert G. Maki
      Pages 275-281
    15. Alveolar Soft Part Sarcoma

      • Murray F. Brennan, Cristina R. Antonescu, Kaled M. Alektiar, Robert G. Maki
      Pages 283-289

About this book

Management of Soft Tissue Sarcoma, 2nd Edition provides the most comprehensive analysis of demographics and natural history currently available for  these lesions, based on the authors’ experience with over 10,000 patients. Sections regarding radiation therapy not found in the previous text have been expanded, as have updates on molecular characteristics of sarcomas and chemotherapy studies published since the prior edition. Clinical and molecular diagnoses are addressed, and tumor histopathology is employed as the basis of treatment recommendations including surgery, radiation and systemic therapy. This is the first book to provide specific chemotherapy opinions for every sarcoma subtype. Written by four world-renowned experts, this book gives a practical, up-to-date approach to managing the many subtypes of adult soft tissue sarcoma.


Reviews from the first edition:

“This is an impressive book. Written by a surgeon, a pathologist and an oncologist, the book draws heavily on the Memorial Sloan-Kettering Cancer Center soft tissue sarcoma (STS) database. … it is a book that should be in the library of any sarcoma unit and will appeal to the sub-specialist in Orthopaedic Oncology.” (Robert U. Ashford, European Journal of Orthopaedic Surgery & Traumatology, Vol. 24, 2014)


“The book is laid out in 27 chapters, with an impressive inclusion of a wide array of sarcoma histology. One of the real strengths of the book is the quality and number of images, figures, tables, and graphs. … The overall outline of the text is well done. … This book is a unique and important addition to the sarcoma literature. … this edtion should find itself on every medical oncologist’s bookshelf … .” (Larry C. Daugherty and Sanjay P. Bagaria, Journal of Radiation Oncology, Vol. 3, 2014)

Authors and Affiliations

  • International Center Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, USA

    Murray F. Brennan

  • Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, USA

    Cristina R. Antonescu

  • Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, USA

    Kaled M. Alektiar

  • Monter Cancer Center, Hofstra Northwell School of Medicine and Cold Spring Harbor Laboratory, Lake Success, USA

    Robert G. Maki

About the authors

Murray F. Brennan, MD
International Center & Department of Surgery
Memorial Sloan-Kettering Cancer Center
New York, NY


Cristina R. Antonescu, MD
Department of Pathology
Memorial Sloan-Kettering Cancer Center
New York, NY


Kaled M. Alektiar, MD
Department of Radiation Oncology
Memorial Sloan-Kettering Cancer Center
New York, NY


Robert G. Maki, MD, PhD
Great Neck, NY


Cold Spring Harbor Laboratory 
Cold Spring Harbor, NY





Bibliographic Information

  • Book Title: Management of Soft Tissue Sarcoma

  • Authors: Murray F. Brennan, Cristina R. Antonescu, Kaled M. Alektiar, Robert G. Maki

  • DOI: https://doi.org/10.1007/978-3-319-41906-0

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing Switzerland 2016

  • Hardcover ISBN: 978-3-319-41904-6Published: 22 December 2016

  • Softcover ISBN: 978-3-319-82460-4Published: 30 April 2018

  • eBook ISBN: 978-3-319-41906-0Published: 15 December 2016

  • Edition Number: 2

  • Number of Pages: XVI, 399

  • Number of Illustrations: 104 b/w illustrations, 234 illustrations in colour

  • Topics: Oncology, Surgical Oncology

Buy it now

Buying options

eBook USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access