Overview
- Presents a comprehensive collection of reviews on the multiple facets of inflammasome signal transduction
- Discusses the latest insights into the major components of known canonical and non-canonical inflammasome complexes
- Offers a valuable resource both for readers new to the field and for professionals already working in the area of inflammasomes
- Includes supplementary material: sn.pub/extras
Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 397)
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Table of contents (13 chapters)
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Front Matter
Keywords
- Inflammasome biology
- Salmonella enterica
- Yersinia pestis
- Shigella flexneri
- Helicobacter pylori
- LIsteria monocytogenes
- Legionella pneumophila
- Mycobacterium
- Burkholderia pseudomallei
- Streptococcus pneumoniae
- Franciscella tularensis
- Staphylococcus aureus
- NLR inflammasome
- Cytosolic bacteriolysis
- Tumor immunotherapy
- infectious diseases
About this book
This volume details our current understanding of the architecture and signaling capabilities of known canonical and non-canonical inflammasome complexes and highlights their action, in particular in response to infection with important bacterial model organisms and the corresponding disease pathologies. The first chapters review new insights into the assembly and structures of inflammasome components and emphasize general strategies of up- and downstream signaling events. In addition, the authors specifically discuss the composition and activity of inflammasomes during infection with various gut pathogens (Salmonella, Shigella, Yersinia, Listeria and Helicobacter), respiratory pathogens (Mycobacterium, Legionella, Burkholderia and Streptococcus) as well as skin and soft tissue pathogens (Francisella and Staphylococcus). The discoveries presented provide a better understanding of the cellular and molecular biology of inflammasomes, which will pinpoint important new therapeutic targets for the treatment and prevention of multiple infectious diseases in the future. It is a valuable resource for students, scientists and clinicians, providing up-to-date information on this emerging research topic.
Editors and Affiliations
About the editor
Bibliographic Information
Book Title: Inflammasome Signaling and Bacterial Infections
Editors: Steffen Backert
Series Title: Current Topics in Microbiology and Immunology
DOI: https://doi.org/10.1007/978-3-319-41171-2
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2016
Hardcover ISBN: 978-3-319-41170-5Published: 08 August 2016
Softcover ISBN: 978-3-319-82285-3Published: 07 June 2018
eBook ISBN: 978-3-319-41171-2Published: 26 July 2016
Series ISSN: 0070-217X
Series E-ISSN: 2196-9965
Edition Number: 1
Number of Pages: XI, 282
Number of Illustrations: 1 b/w illustrations, 28 illustrations in colour
Topics: Medical Microbiology, Infectious Diseases, Parasitology, Pneumology/Respiratory System