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Immune Infertility

Impact of Immune Reactions on Human Fertility

  • Covers basic and clinical aspects of immune reactions in infertility
  • Represents the standard work on immune infertility
  • Fully updated to reflect the important advances achieved over recent years

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Table of contents (19 chapters)

  1. Front Matter

    Pages i-xi
  2. Sperm Antigens

    1. Front Matter

      Pages 1-1
    2. Proteomic Analysis of Human Spermatozoa

      • Brett Nixon, Matthew D. Dun, R. John Aitken
      Pages 3-22
    3. Methods of Analysis of Sperm Antigens Related to Fertility

      • Jagathpala Shetty, Nicholas E. Sherman, John C. Herr
      Pages 23-47
    4. Sperm Surface Proteomics

      • Ian A. Brewis, Barend M. Gadella
      Pages 49-76
    5. Sperm Functions Influenced by Immune Reactions

      • Walter K. H. Krause
      Pages 77-93
  3. Antisperm Antibodies (ASA)

    1. Front Matter

      Pages 95-95
    2. The Immune Privilege of the Testis

      • Monika Fijak, Sudhanshu Bhushan, Andreas Meinhardt
      Pages 97-107
    3. Immune Chemistry of ASA

      • Maciej Kurpisz, Marzena Kamieniczna, Karolina Nowicka-Bauer
      Pages 109-123
    4. Sperm-Specific T Lymphocytes

      • Michael Hertl, Walter K. H. Krause
      Pages 125-132
    5. Biologic Substrates Containing ASA

      • Walter K. H. Krause
      Pages 149-159
    6. ASA in the Female

      • Gary N. Clarke
      Pages 161-171
    7. Sperm Immobilizing Antibody and Its Target Antigen

      • Akiko Hasegawa, Minoru Shigeta, Hiroaki Shibahara
      Pages 173-184
  4. The Clinical Impact of Sperm Antibodies

    1. Front Matter

      Pages 185-185
    2. Male Autoimmune Infertility

      • Felice Francavilla, Arcangelo Barbonetti
      Pages 187-196
    3. Tests for Sperm Antibodies

      • Tamer M. Said, Ashok Agarwal
      Pages 197-207
    4. Impact on Fertility Outcome

      • Zdenka Ulcova-Gallova, Petr Losan
      Pages 209-221
    5. Sperm Antibodies and Assisted Reproduction

      • Jerome H. Check, Jasmine Aly
      Pages 223-234

About this book

            
This book offers  comprehensive coverage of both basic and clinical aspects of immune reactions responsible for infertility. It has  four sections focusing on Sperm antigens, Antisperm antibodies (ASAs),  Clinical impact of ASAs, and Immune contraception,  and include contributions from leading experts in these fields. This new edition of the book offers a comprehensive update that reflects the very significant advances in reproductive immunology that have been achieved over the past five years, especially related  to the sperm proteome, sperm-egg binding/fusion proteins, gene knockout studies, and immunocontraception. Reproductive immunology continues to be a fast-growing discipline in which new knowledge is emerging almost every day. Immune Infertility is a model source of vital and reliable information on the latest scientific developments in the field. It will be of value for clinicians, scientists, students, residents, and fellows working in reproductive biology, obstetrics and gynecology, and urology.

Editors and Affiliations

  • Department of Dermatology and Allergology, University Hospital, Philipp University, Marburg, Germany

    Walter K.H. Krause

  • Department of Obstetrics and Gynecology, School of Medicine, West Virgina University, Morgantown, USA

    Rajesh K. Naz

About the editors

Walter Krause completed his medical studies at the University of Gießen, Germany, in 1965 and subsequently completed a residency in the Clinic of Dermatology at the university. He qualified as a Specialist in Dermatology in 1971 and completed his "Habilitation" in 1976. In 1984 Dr. Krause was appointed Head of the Department of Andrology at the Clinic of Dermatology, University of Marburg, and in 1996 the department became a Clinical Training Center of the European Academy of Andrology. In 2005 Dr. Krause was appointed Emeritus Professor. His particular interests have included diagnosis of male fertility disorders, diagnosis and treatment of male sexual disorders, male sexual endocrine dysfunctions, male immune infertility, and endocrine diseases and the skin. He has an extensive publication record, including 5 textbooks,50 book chapters, and 379 journal articles, and he has delivered 450 oral presentations. 

Rajesh Kumar Naz is a Professor at West Virginia University, School of Medicine, Morgantown, WV, USA, where he is Vice Chair for Research in the Department of Obstetrics and Gynecology. The objective of his research has been to develop novel, nonsteroidal contraceptives with microbicidal properties and methods for the specific diagnosis of and treatment modalities for vaginal infections and infertility in humans. Dr. Naz has trained over 58 postdoctoral fellows and graduate students. He is a member of 14 editorial boards of a number of journals. Dr. Naz has published more than 215 full-length peer-reviewed articles in prestigious journals and edited/authored eight books in the fields of immunocontraception and infertility. In 2011 he edited the special issue of the American Journal of Reproductive Immunology on contraceptive vaccines.


Bibliographic Information

  • Book Title: Immune Infertility

  • Book Subtitle: Impact of Immune Reactions on Human Fertility

  • Editors: Walter K.H. Krause, Rajesh K. Naz

  • DOI: https://doi.org/10.1007/978-3-319-40788-3

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing Switzerland 2017

  • Hardcover ISBN: 978-3-319-40786-9Published: 15 November 2016

  • Softcover ISBN: 978-3-319-82183-2Published: 27 June 2018

  • eBook ISBN: 978-3-319-40788-3Published: 02 November 2016

  • Edition Number: 2

  • Number of Pages: XI, 302

  • Number of Illustrations: 14 b/w illustrations, 19 illustrations in colour

  • Topics: Reproductive Medicine, Gynecology, Urology, Immunology, General Practice / Family Medicine, Dermatology

Buy it now

Buying options

eBook USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 179.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access