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  • Book
  • © 2016

Glial Cells in Health and Disease of the CNS

  • Covers each of the three major types of glial cells in the CNS
  • Timely overview of a growing topic
  • Gathers contributions from leading researchers in the field
  • Includes supplementary material: sn.pub/extras

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 949)

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-xi
  2. Glial Cells and Integrity of the Nervous System

    • Rommy von Bernhardi, Jaime Eugenín-von Bernhardi, Betsi Flores, Jaime Eugenín León
    Pages 1-24
  3. Glial Cell Function in the Healthy Nervous System

    1. Front Matter

      Pages 25-25
    2. NG2-glia, More Than Progenitor Cells

      • Jaime Eugenín-von Bernhardi, Leda Dimou
      Pages 27-45
    3. Pharmacological Tools to Study the Role of Astrocytes in Neural Network Functions

      • Fernando Peña-Ortega, Ana Julia Rivera-Angulo, Jonathan Julio Lorea-Hernández
      Pages 47-66
    4. Microglia Function in the Normal Brain

      • Rommy von Bernhardi, Florencia Heredia, Nicole Salgado, Paola Muñoz
      Pages 67-92
    5. Role of Astrocytes in Central Respiratory Chemoreception

      • Jaime Eugenín León, María José Olivares, Sebastián Beltrán-Castillo
      Pages 109-145
    6. Purine Signaling and Microglial Wrapping

      • Bernardo Castellano, Mar Bosch-Queralt, Beatriz Almolda, Nàdia Villacampa, Berta González
      Pages 147-165
  4. Glial Cell Dysfunction and Pathological Implications

    1. Front Matter

      Pages 203-203
    2. Age-Dependent Changes in the Activation and Regulation of Microglia

      • Francisca Cornejo, Rommy von Bernhardi
      Pages 205-226
    3. Astrocyte Dysfunction in Developmental Neurometabolic Diseases

      • Silvia Olivera-Bravo, Eugenia Isasi, Anabel Fernández, Gabriela Casanova, Juan Carlos Rosillo, Luigi Barbeito
      Pages 227-243
    4. Microglia in Cancer: For Good or for Bad?

      • Anna Carolina Carvalho da Fonseca, Rackele Amaral, Celina Garcia, Luiz Henrique Geraldo, Diana Matias, Flavia Regina Souza Lima
      Pages 245-261
    5. Peripheral Inflammation and Demyelinating Diseases

      • Verónica Murta, Carina Ferrari
      Pages 263-285
    6. Regulation of Oligodendrocyte Differentiation and Myelination by Nuclear Receptors: Role in Neurodegenerative Disorders

      • Adrián Sandoval-Hernández, María José Contreras, Jenny Jaramillo, Gonzalo Arboleda
      Pages 287-310
    7. Prenatal Systemic Hypoxia-Ischemia and Oligodendroglia Loss in Cerebellum

      • Penha Cristina Barradas, Tiago Savignon, Alex C. Manhães, Frank Tenório, Alan P. da Costa, Marta C. Cunha-Rodrigues et al.
      Pages 333-345
  5. Back Matter

    Pages 347-348

About this book

A timely overview covering the three major types of glial cells in the central nervous system - astrocytes, microglia, and oligodendrocytes. New findings on glia biology are overturning a century of conventional thinking about how the brain operates and are expanding our knowledge about information processing in the brain. The book will present recent research findings on the role of glial cells in both healthy function and disease. It will comprehensively cover a broad spectrum of topics while remaining compact in size.

Editors and Affiliations

  • Faculty of Medicine Professor of Neurology, Pontificia Universidad Católica de Chile, Santiago, Chile

    Rommy von Bernhardi

About the editor

Rommy von Bernhardi is professor of Neurology at the School of Medicine, Pontificia Universidad Católica de Chile (Santiago, Chile) and head of the Neuroscience lab. She obtained her Ph.D. in Neuroscience at the Universität Basel (Basel, Switzerland). Her research areas of interest concern: the biological mechanisms of clinical diseases of the CNS--particularly Alzheimer's disease and neurodegenerative pathology; as well as the functional and disease-related role of glial cells in the inflammation of the nervous system. She is coauthor and coeditor of over 80 scientific publications. Dr. Von Bernhardi is also a member of several distinguished societies such as the Society for Neuroscience and the International Brain Research Organization (IBRO); she was president of the Sociedad Chilena Neurociencia and is currently head of FALAN (Federación Latinoamericana y del Caribe de Neurociencia). 

Bibliographic Information

  • Book Title: Glial Cells in Health and Disease of the CNS

  • Editors: Rommy von Bernhardi

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-3-319-40764-7

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2016

  • Hardcover ISBN: 978-3-319-40762-3Published: 13 October 2016

  • Softcover ISBN: 978-3-319-82176-4Published: 16 June 2018

  • eBook ISBN: 978-3-319-40764-7Published: 06 October 2016

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XI, 348

  • Number of Illustrations: 11 b/w illustrations, 35 illustrations in colour

  • Topics: Neurosciences

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access