Overview
- Written by recognized authorities in the fields
- Providing comprehensive and up-to-date reviews in the topic
- Well-known series
Part of the book series: Progress in the Chemistry of Organic Natural Products (POGRCHEM, volume 102)
Access this book
Tax calculation will be finalised at checkout
Other ways to access
Table of contents (2 chapters)
Keywords
About this book
The first contribution reviews the phytochemical, chemical,
and biological literature on members of the ingenane class of diterpenoids from
their first isolation in 1968 through 2015, highlighting unresolved issues both
common to phorboids and specific to ingenol derivatives. The biogenesis of ingenol is discussed in the
light of the Jakupovic proposal of a dissection between the formation of the macrocyclic
Euphorbia diterpenoids and the phorboids,
and the clinical development of ingenol mebutate is chronicled in the light of
its “reverse-pharmacology” focus.
The second contribution
offers a comprehensive view of the chemical wealth and the taxonomic problems
currently impeding chemical and biological investigations of the genus Laurencia. It addresses the botanical description and the growth and
population dynamics of the genus, as well as its chemical diversity and ecological
relations; the secondary metabolites as well as their sources of isolation; and finally the biological activity.
Editors and Affiliations
Bibliographic Information
Book Title: Progress in the Chemistry of Organic Natural Products 102
Editors: A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Jun'ichi Kobayashi
Series Title: Progress in the Chemistry of Organic Natural Products
DOI: https://doi.org/10.1007/978-3-319-33172-0
Publisher: Springer Cham
eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2016
Hardcover ISBN: 978-3-319-33170-6Published: 15 July 2016
Softcover ISBN: 978-3-319-81445-2Published: 31 May 2018
eBook ISBN: 978-3-319-33172-0Published: 05 July 2016
Series ISSN: 2191-7043
Series E-ISSN: 2192-4309
Edition Number: 1
Number of Pages: V, 252
Number of Illustrations: 180 b/w illustrations, 10 illustrations in colour
Topics: Organic Chemistry, Medicinal Chemistry, Medical Biochemistry