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Autophagy at the Cell, Tissue and Organismal Level

  • Book
  • © 2016

Overview

Authors:
  1. Eleftherios Karanasios

    1. Babraham Institute, Babraham, Cambridge, United Kingdom

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    You can also search for this author in PubMed   Google Scholar

  2. Nicholas T. Ktistakis

    1. Babraham Institute, Babraham, Cambridge, United Kingdom

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    You can also search for this author in PubMed   Google Scholar

  • Covers autophagy from the basic mechanisms to its effects at the cell, tissue and organism level
  • Includes an extensive list of antibodies for the study of autophagy
  • Written by experts in the field
  • Includes supplementary material: sn.pub/extras

Part of the book series: SpringerBriefs in Cell Biology (SBCB)

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Table of contents (6 chapters)

  1. Front Matter

    Pages i-vi
    Download chapter PDF

  2. Autophagy (Autophagia) from 1860 to 1963

    • Eleftherios Karanasios, Nicholas T. Ktistakis
    Pages 1-5

  3. History of Autophagy After 1963

    • Eleftherios Karanasios, Nicholas T. Ktistakis
    Pages 7-15

  4. Signalling in Autophagy

    • Eleftherios Karanasios, Nicholas T. Ktistakis
    Pages 17-33

  5. Autophagosome Formation

    • Eleftherios Karanasios, Nicholas T. Ktistakis
    Pages 35-50

  6. Physiological Role of Autophagy and Implications in Disease

    • Eleftherios Karanasios, Nicholas T. Ktistakis
    Pages 51-80

  7. Studying Autophagy: List of Useful Antibodies Produced via a Community Effort

    • Eleftherios Karanasios, Nicholas T. Ktistakis
    Pages 81-103
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Keywords

About this book

This book provides an expert summary of autophagy, a relatively new but rapidly expanding field of biomedical science with important implications in health and disease. After a historical review ranging up to the identification of autophagy genes in mammals, the authors discuss the signaling pathways that regulate autophagy, the mechanism of autophagosome formation and the physiological roles of autophagy in development, ageing, neurodegeneration, immune function and cell differentiation. A comprehensive list of useful antibodies for studying autophagy compiled as a community effort is included at the end. The book is intended for newcomers to the field, as well as more experienced researchers looking for a condensed but comprehensive introduction to the physiological function and regulation of the autophagic pathway in mammalian organisms.

Authors and Affiliations

  • Babraham Institute, Babraham, Cambridge, United Kingdom

    Eleftherios Karanasios, Nicholas T. Ktistakis

Bibliographic Information

  • Book Title: Autophagy at the Cell, Tissue and Organismal Level

  • Authors: Eleftherios Karanasios, Nicholas T. Ktistakis

  • Series Title: SpringerBriefs in Cell Biology

  • DOI: https://doi.org/10.1007/978-3-319-33145-4

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Author(s) 2016

  • Softcover ISBN: 978-3-319-33143-0Published: 04 May 2016

  • eBook ISBN: 978-3-319-33145-4Published: 23 April 2016

  • Series ISSN: 2625-3534

  • Series E-ISSN: 2625-3542

  • Edition Number: 1

  • Number of Pages: VI, 103

  • Number of Illustrations: 3 b/w illustrations, 12 illustrations in colour

  • Topics: Cell Biology, Immunology, Animal Biochemistry

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