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Vitamin D in Chronic Kidney Disease

  • Book
  • © 2016

Overview

Editors:
  1. Pablo A. Ureña Torres

    1. Ramsay-Générale de Santé, Clinique du Landy, Saint Ouen, France

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  2. Mario Cozzolino

    1. San Paolo Hospital, DiSS University of Milan, Milan, Italy

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  3. Marc G. Vervloet

    1. VU University Medical Center, Amsterdam, The Netherlands

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  • This book will focus on vitamin D in Chronic Kidney Disease states

  • Discusses recent insights on vitamin D metabolism as well as its association with a diversity of non-skeletal complications, among them cardiovascular disease, diabetes mellitus, multiple sclerosis, cancer, tuberculosis, and immune system dysfunction

  • New players in the regulation of vitamin synthesis and degradation have been identified and largely explored in case of CKD including FGF23 and klotho

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Table of contents (31 chapters)

  1. Front Matter

    Pages i-xxviii
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  2. Generalities, Measurement and Epidemiology

    1. Front Matter

      Pages 1-1
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    2. Vitamin D Metabolism in Normal and Chronic Kidney Disease States

      • Claudia Zierold, Kevin J. Martin, Hector F. DeLuca
      Pages 3-17

    3. Epidemiology of Vitamin D Deficiency in Chronic Kidney Disease

      • Marie Metzger, Bénédicte Stengel
      Pages 19-50

    4. Molecular Biology of Vitamin D: Genomic and Nongenomic Actions of Vitamin D in Chronic Kidney Disease

      • Adriana S. Dusso
      Pages 51-74

    5. Vitamin D Receptor and Interaction with DNA: From Physiology to Chronic Kidney Disease

      • Jordi Bover, César Emilio Ruiz, Stefan Pilz, Iara Dasilva, Montserrat M. Díaz, Elena Guillén
      Pages 75-116

    6. Measurement of Circulating 1,25-Dihydroxyvitamin D and Vitamin D–Binding Protein in Chronic Kidney Diseases

      • Etienne Cavalier, Pierre Delanaye
      Pages 117-128

  3. Classical Mineral and Bone Effects

    1. Front Matter

      Pages 129-129
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    2. Vitamin D and Racial Differences in Chronic Kidney Disease

      • Orlando M. Gutiérrez
      Pages 131-145

    3. Vitamin D and Parathyroid Hormone Regulation in Chronic Kidney Disease

      • María E. Rodríguez-Ortiz, Mariano Rodríguez, Yolanda Almadén Peña
      Pages 147-161

    4. The Parathyroid Type I Receptor and Vitamin D in Chronic Kidney Disease

      • Pablo A. Ureña Torres, Jordi Bover, Pieter Evenepoel, Vincent Brandenburg, Audrey Rousseaud, Franck Oury
      Pages 163-177

    5. Vitamin D and Klotho in Chronic Kidney Disease

      • Hirotaka Komaba, Beate Lanske
      Pages 179-194

    6. Vitamin D and FGF23 in Chronic Kidney Disease

      • Dominique Prié
      Pages 195-206

    7. Wnt/Sclerostin and the Relation with Vitamin D in Chronic Kidney Disease

      • Mugurel Apetrii, Adrian Covic
      Pages 207-216

    8. Vitamin D and Bone in Chronic Kidney Disease

      • Martine Cohen-Solal, Pablo A. Ureña Torres
      Pages 217-228

    9. Vitamin D in Children with Chronic Kidney Disease: A Focus on Longitudinal Bone Growth

      • Justine Bacchetta, Isidro B. Salusky
      Pages 229-245

  4. Non-classical Effects of Vitamin D

    1. Front Matter

      Pages 247-247
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    2. Vitamin D and Progression of Renal Failure

      • Marc De Broe
      Pages 249-265

    3. Vitamin D and Diabetes in Chronic Kidney Disease

      • Emilio González Parra, Maria Luisa González-Casaus, Ricardo Villa-Bellosta
      Pages 267-283

    4. Vitamin D and Muscle in Chronic Kidney Disease

      • Philippe Chauveau, Michel Aparicio
      Pages 285-293
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Keywords

About this book

Vitamin D deficiency, circulating levels lower than 15 ng/ml, is an epidemic disease worldwide with  more than a billion people suffering of it in the beginning of the 21-century. Besides its impact on mineral and bone metabolism, these low vitamin D levels are also associated with a diversity of non-skeletal complications, among them cardiovascular disease, diabetes mellitus, multiple sclerosis, cancer, tuberculosis, and immune system dysfunction. Chronic Kidney Disease is also a very common disease, affecting more than 10% of the world population, ranging from stage 1 to stage 5 before dialysis. Approximately 1% of the population in industrialized countries is affected by end-stage renal disease (ESRD), needing a renal replacement therapy either hemodialysis or peritoneal dialysis, and ultimately by renal transplantation. Those CKD patients are more susceptible to exhibit reduced vitamin D stocks. Consequently, more than eighty percent of CKD patients have either insufficient or deficient vitamin D levels for multiple reasons.

Editors and Affiliations

  • Ramsay-Générale de Santé, Clinique du Landy, Saint Ouen, France

    Pablo A. Ureña Torres

  • San Paolo Hospital, DiSS University of Milan, Milan, Italy

    Mario Cozzolino

  • VU University Medical Center, Amsterdam, The Netherlands

    Marc G. Vervloet

About the editors

Pablo URENA TORRES, M.D., Ph.D.
Department of Nephrology and Dialysis. Clinique du Landy. 23, rue du Landy. 93400 Saint Ouen, France, and Department of Department of Renal Physiology. Necker Hospital, University of Paris Descartes, Paris, France


Mario COZZOLINO, M.D. Ph.D.
Department of Health Sciences, Renal Division, San Paolo Hospital, University of Milan, Milan, Italy


Marc G. VERVLOET, M.D., Ph.D.
Department of Nephrology, VU University Medical Center, Amsterdam, The Netherlands

Bibliographic Information

  • Book Title: Vitamin D in Chronic Kidney Disease

  • Editors: Pablo A. Ureña Torres, Mario Cozzolino, Marc G. Vervloet

  • DOI: https://doi.org/10.1007/978-3-319-32507-1

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing Switzerland 2016

  • Hardcover ISBN: 978-3-319-32505-7Published: 05 October 2016

  • Softcover ISBN: 978-3-319-81302-8Published: 27 June 2018

  • eBook ISBN: 978-3-319-32507-1Published: 21 September 2016

  • Edition Number: 1

  • Number of Pages: XXVIII, 574

  • Number of Illustrations: 15 b/w illustrations, 51 illustrations in colour

  • Topics: Nephrology, Clinical Nutrition, Endocrinology

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