Overview
- Provides a comprehensive overview of the early development of the gonads
- Includes a particular focus on the mouse
- Offers detailed reviews written by international experts
Part of the book series: Results and Problems in Cell Differentiation (RESULTS, volume 58)
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Table of contents (14 chapters)
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Front Matter
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Back Matter
Keywords
About this book
This book presents the current state of knowledge on the origin and differentiation of cell lines involved in the development of the vertebrate male and female gonads with particular emphasis on the mouse. It also discusses the processes leading to the testis- and ovary-specific structures and functions.
The individual chapters review the origin and differentiation of the somatic cells of the genital ridges; the formation and migration of primordial germ cells in mouse and man; the gonadal supporting cell lineage and mammalian sex determination; differentiation of Sertoli and granulosa cells; mesonephric cell migration into the gonads and vascularization; origin and differentiation of androgen-producing cells in the gonads; germ cell commitment to the oogenic versus spermatogenic pathway and the role of retinoic acid; ovarian folliculogenesis; control of oocyte growth and development by intercellular communication within the follicular niche; biology of the Sertoli cell in the fetal, pubertal and adult mammalian testis; mechanisms regulating spermatogonial differentiation; stem cells in mammalian gonads; the role of microRNAs in cell differentiation during gonad development; human sex development and its disorders; as well as methods for the study of gonadal development.
Editors and Affiliations
About the editor
Bibliographic Information
Book Title: Molecular Mechanisms of Cell Differentiation in Gonad Development
Editors: Rafal P. Piprek
Series Title: Results and Problems in Cell Differentiation
DOI: https://doi.org/10.1007/978-3-319-31973-5
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing Switzerland 2016
Hardcover ISBN: 978-3-319-31971-1Published: 22 June 2016
Softcover ISBN: 978-3-319-81167-3Published: 31 May 2018
eBook ISBN: 978-3-319-31973-5Published: 14 June 2016
Series ISSN: 0080-1844
Series E-ISSN: 1861-0412
Edition Number: 1
Number of Pages: XII, 434
Number of Illustrations: 4 b/w illustrations, 48 illustrations in colour
Topics: Developmental Biology, Stem Cells, Cytogenetics, Molecular Medicine, Reproductive Medicine