Cranial Osteomyelitis

1. Front Matter

   Pages i-xvii

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2. General Introduction

   1. Front Matter

      Pages 1-1

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   2. Introduction, Definitions and Historical Aspects

      • Ali Akhaddar

      Pages 3-15

3. Basic Information for Cranial Osteomyelitis

   1. Front Matter

      Pages 17-17

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   2. Epidemiology and Risk Factors

      • Ali Akhaddar

      Pages 19-43

   3. Different Pathogens Involved

      • Ali Akhaddar

      Pages 45-61

   4. Histopathologic Changes

      • Ali Akhaddar

      Pages 63-75

   5. Pathophysiology and Anatomical Spreads of Infection

      • Ali Akhaddar

      Pages 77-100

4. Diagnosis of Cranial Osteomyelitis

   1. Front Matter

      Pages 101-101

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   2. Main Clinical Presentations

      • Ali Akhaddar

      Pages 103-119

   3. Laboratory Findings

      • Ali Akhaddar

      Pages 121-128

   4. Imaging Studies

      • Ali Akhaddar

      Pages 129-158

   5. Differential Diagnoses: Clinical and Imaging

      • Ali Akhaddar

      Pages 159-188

5. Management of Cranial Osteomyelitis

   1. Front Matter

      Pages 189-189

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   2. General Considerations and Surgical Therapy

      • Ali Akhaddar

      Pages 191-223

   3. Antimicrobial and Medical Therapy

      • Ali Akhaddar

      Pages 225-235

   4. Adjuvant Hyperbaric Oxygen Therapy

      • Ali Akhaddar

      Pages 237-247

   5. Outcomes and Prognoses

      • Ali Akhaddar

      Pages 249-256

6. Special Conditions in Cranial Osteomyelitis

   1. Front Matter

      Pages 257-257

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   2. Unusual Pathogens

      • Ali Akhaddar

      Pages 259-283

This book is the first reference book covering exclusively all aspects of this challenging disease. It is designed to serve as a succinct appropriate resource for neurosurgeons, otorhinolaryngologists, neuroradiologists, researchers and infectious disease specialists with an interest in cranial infection. Cranial Osteomyelitis provides an in-depth review of knowledge of the management of skull osteomyelitis, with an emphasis on risk factors, causative pathogens, pathophysiology of dissemination, clinical presentations, neuroradiological findings and treatment modalities, medical and surgical. Sections on the prognosis and prevention of this illness are also included. The book will help the reader in choosing the most appropriate way to manage this challenging bone infection. In addition, it supplies clinicians and investigators with both basic and more sophisticated information and procedures relating to the complications associated with skull osteomyelitis. It also considers future areas of investigation and innovative therapeutic philosophies. The book is richly illustrated to provide readers with unparalleled access to a comprehensive collection of cranial osteomyelitis images (biological, clinical, neuroradiological, and surgical) taken directly from the author’s collection and experience in the field.

• Cellulitis
• Garré’s disease
• Hyperbaric Oxygen therapy
• Mucocele
• Physiopathology
• infectious diseases

“This unique reference book is well organized into six main parts containing a total of 16 chapters … . we strongly recommend this unique work as a practical and quick source of information for all pediatric neurosurgeons and neurologists, radiologists, and infectious disease consultants who feel a need to fill a gap in their knowledge base.” (Ahmet T. Turgut and Mehmet Turgut, Child's Nervous System, November, 2016)

• Department of Neurosurgery , University of Mohammed V in Rabat, Avicenne Military Hospital of Marrakech, Marrakech, Morocco

  Ali Akhaddar

Ali AKHADDAR, MD, is Professor of Neurosurgery at the Faculty of Medicine, Mohammed V University in Rabat (Morocco) and Chairman of the Department of Neurosurgery at Avicenne Military Hospital of Marrakech (Morocco). He is an Expert Member of the Scientific Committees of the National Scientific and Technological Research Center of Morocco (CNRST). Dr Akhaddar is a Member of the American Association of Neurological Surgeons (AANS), the Congress of Neurological Surgeons (CNS), the French speaking society of Neurosurgery (SNCLF) and the Military Neurosurgeons Committee in the World Federation of Neurosurgical Societies (WFNS). He has received many awards during his career, including from the Moroccan Society of Neurosurgery, the World Federation of Neurosurgical Societies [Traveling Fellowship Award: Nagoya 2007, Boston 2009 and Seoul 2013], the University of Mohammed V of Rabat and the French Society of Hospitals’ History (SFHH).Dr Akhaddar is a member of the editorial board of theOpen Neurosurgery Journal and Médecine du Maghreb and is a reviewing editor for many medical journals. He is the author of three previous books; he has authored and co-authored more than 200 papers published in peer-reviewed journals (140 indexed in PubMed*) and five book chapters.

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