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  • © 2016

Metabolic Control

Editors:

  • The book covers a broad range of topics in metabolic research, ranging from key molecular events to therapeutic options in metabolic disorders
  • This book gives a comprehensive overview over the current state-of-the-art in metabolic regulation and dysfunction
  • The book provides an update on classical components of metabolic control and also highlights novel and emerging areas in this field in an integrated manner

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 233)

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-viii
  2. A Genome-Wide Perspective on Metabolism

    • Alexander Rauch, Susanne Mandrup
    Pages 1-28
  3. Role of the cAMP Pathway in Glucose and Lipid Metabolism

    • Kim Ravnskjaer, Anila Madiraju, Marc Montminy
    Pages 29-49
  4. Glucocorticoids and Metabolic Control

    • Lilia Magomedova, Carolyn L. Cummins
    Pages 73-93
  5. Nuclear Receptor Coregulators in Metabolism and Disease

    • Marco Giudici, Saioa Goni, Rongrong Fan, Eckardt Treuter
    Pages 95-135
  6. Incretins

    • Tongzhi Wu, Christopher K. Rayner, Michael Horowitz
    Pages 137-171
  7. Neural Control of Energy Expenditure

    • Heike Münzberg, Emily Qualls-Creekmore, Hans-Rudolf Berthoud, Christopher D. Morrison, Sangho Yu
    Pages 173-194
  8. Signalling Networks Governing Metabolic Inflammation

    • Nassim Dali-Youcef, Romeo Ricci
    Pages 195-220
  9. Immune Cells and Metabolism

    • Antonios Chatzigeorgiou, Triantafyllos Chavakis
    Pages 221-249
  10. Adipose Tissue Stem Cells

    • Sebastian Müller, Elisabeth Kulenkampff, Christian Wolfrum
    Pages 251-263
  11. Adipokines and the Endocrine Role of Adipose Tissues

    • Marta Giralt, Rubén Cereijo, Francesc Villarroya
    Pages 265-282
  12. cGMP and Brown Adipose Tissue

    • Linda S. Hoffmann, Christopher J. Larson, Alexander Pfeifer
    Pages 283-299
  13. Brown Adipose Tissue: A Human Perspective

    • Mariëtte R. Boon, Wouter D. van Marken Lichtenbelt
    Pages 301-319
  14. Organ-Specific Cancer Metabolism and Its Potential for Therapy

    • Ilaria Elia, Roberta Schmieder, Stefan Christen, Sarah-Maria Fendt
    Pages 321-353
  15. Metabolic Syndrome, Type 2 Diabetes, and Cancer: Epidemiology and Potential Mechanisms

    • Sarit Ben-Shmuel, Ran Rostoker, Eyal J. Scheinman, Derek LeRoith
    Pages 355-372
  16. Current and Emerging Treatment Options in Diabetes Care

    • Christoffer Clemmensen, Timo D. Müller, Brian Finan, Matthias H. Tschöp, Richard DiMarchi
    Pages 437-459
  17. Back Matter

    Pages 461-469

About this book

The HEP issue on Metabolic Control provides a state-of the art overview over both classical concepts and emerging areas in metabolism and associated disorders. In this context, metabolic control is highlighted at various levels of complexity ranging from transcriptional mechanisms in metabolic pathway control over metabolic communication routes in physiology and pathophysiology to current treatment modalities and options in metabolic disorders, including type 2 diabetes and obesity. Dedicated chapters by leading experts in their fields provide a concise overview over important areas in metabolic research at a molecular level, including the role of the central nervous system in metabolism, inflammation and metabolism, pancreatic hormone signaling, brown adipose tissue, and therapeutic concepts.

Editors and Affiliations

  • Helmholtz Center Munich, and Heidelberg University Hospital, Professor and Director, Institute for Diabetes and Cancer IDC, and Joint Heidelberg-IDC Translational Diabetes Program, Neuherberg, Germany

    Stephan Herzig

About the editor

Stephan Herzig obtained his PhD from the University of Göttingen, Germany, in 1999. Supported by the German Research Foundation DFG he then joined the Salk Institute for Biological Studies, La Jolla, CA, for his postdoctoral training. In 2004, he established an Emmy-Noether and Marie Curie Junior Research Group at the German Cancer Research Center (DKFZ) in Heidelberg, Germany. He became Head of a Joint Research Division between the DKFZ, Heidelberg University, and Heidelberg University Hospital in 2010, followed by his appointment as a Full W3 Professor at the Medical Faculty of Heidelberg University. Since 2015, Stephan Herzig is the director of the Institute for Diabetesand Cancer (IDC) at the Helmholtz Center Munich and he holds the chair in Molecular Metabolic Control at the Technical University Munich as well as a Honorary Professorship at the Medical Faculty at Heidelberg University. Stephan Herzig studies the molecular mechanisms of severe metabolic disorders and their complications, including insulin resistance, type 2 diabetes, and cancer.

Bibliographic Information

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access