Acquired Neuromuscular Disorders

1. Front Matter

   Pages i-xi

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2. Diagnostic Tools

   1. Front Matter

      Pages 1-1

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   2. Autoantibodies in Neuromuscular Disorders

      • Luis Querol, Eduard Gallardo, Isabel Illa Sendra

      Pages 3-20

   3. Electromyography

      • Lucio Santoro, Fiore Manganelli

      Pages 21-37

   4. Imaging of the Muscle

      • Massimiliano Filosto, Anna Pichiecchio, Alessandro Padovani, Roberto Gasparotti

      Pages 39-53

   5. Peripheral Nerve Ultrasound

      • Luca Padua, Daniele Coraci

      Pages 55-60

   6. Magnetic Resonance Imaging of the Peripheral Nerve

      • Roberto Gasparotti, Massimiliano Filosto

      Pages 61-79

3. Clinical Myology Entities

   1. Front Matter

      Pages 81-81

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   2. The Spectrum of Inflammatory Myopathies: Dermatomyositis, Polymyositis, Necrotizing Myositis, and Inclusion-Body Myositis

      • Marinos C. Dalakas

      Pages 83-98

   3. Necrotizing Autoimmune Myopathy

      • Charles Kassardjian, Margherita Milone

      Pages 99-111

   4. Statin Myopathy

      • Jochen Schaefer, Sandra Jackson

      Pages 113-122

   5. Myasthenia Gravis

      • Amelia Evoli, Raffaele Iorio

      Pages 123-135

   6. Acquired Autoimmune Rippling Muscles with Myasthenia Gravis

      • Carl F. Ansevin

      Pages 137-141

   7. Endocrinological Myopathies

      • Corrado Angelini

      Pages 143-154

   8. Vitamin D Deficiency in Muscle

      • Hussam Abou Al-Shaar, Saeed A. Bohlega

      Pages 155-162

   9. Intensive Care Unit-Acquired Weakness

      • Marija Meznaric, Corrado Angelini

      Pages 163-175

4. Neurogenic Disorders

   1. Front Matter

      Pages 177-177

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   2. Idiopathic Chronic Immune-Mediated Neuropathies: Chronic Inflammatory Demyelinating Polyradiculoneuropathy and Multifocal Motor Neuropathy

      • Eduardo Nobile-Orazio, Francesca Gallia

      Pages 179-191

   3. Immune Neuropathies

      • Darine Kassar, Stanley Iyadurai

      Pages 193-217

   4. Amyotrophic Lateral Sclerosis: Epidemiology and Risk Factors

      • Federico Verde, Nicola Ticozzi

      Pages 219-230

This book provides state of the art information on the pathogenesis, diagnosis, and treatment of a range of inflammatory, autoimmune, and idiopathic neuromuscular disorders. The opening section discusses the differential diagnosis of acquired myopathies based on clinical, electrophysiological, muscle biopsy, and serological criteria, with special focus on the role of electromyography and antibody testing. Each of the relevant clinical entities is then discussed in detail, the coverage including, for example, myasthenia gravis, polymyositis, immune-mediated neuropathies, multifocal motor neuropathies, amyotrophic lateral sclerosis, paraneoplastic neuropathies, and diabetic polyneuropathy. Clear guidance is provided on currently available treatments, with descriptions of the latest advances in physiotherapy, drug therapy, and respiratory care. Other features of this clinically oriented book are the inclusion of many illustrative case presentations and contributions by international authors from leading centers.

• Amyotrophic lateral sclerosis
• Inflammatory myopathies
• Intensive care myopathy
• Motor neurone disease
• Myasthenia gravis
• Polymyositis

• Neuromuscular Center, IRCCS Fondazione San Camillo Hospit, Venice, Italy

  Corrado Angelini

Corrado Angelini is Professor of Neurology and Director of the Neuromuscular Center at the University of Padua, Italy, a position he has held since 1980. Since 2010 he has also been a Consultant at IRCCS Fondazione San Camillo Hospital in Venice. After completing his MD at the University of Padua and specializing in Neurology, Dr. Angelini studied and worked for more than 4 years in the United States (in Minnesota, North Dakota, Colorado, and California) before returning to Italy to take up his position at the University of Padua. Dr. Angelini is an Associate Member of the American Academy of Neurology and has been Chair of the ENS Muscle and Neuromuscular Junction Committee since 2009. He has received several honors during his career and is the author of numerous articles in international peer-reviewed journals. Dr. Angelini is a member of the advisory board of Neurology and Neurological Sciences and a Springer author.

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