Hypertension and Stroke

1. Front Matter

   Pages i-xix

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2. Blood Pressure and Hypertension as Antecedents of Stroke

   1. Front Matter

      Pages 1-1

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   2. Blood Pressure: Definition, Diagnosis, and Management

      • Raymond R. Townsend, Susan P. Steigerwalt

      Pages 3-15

   3. The Link Between Hypertension and Stroke: Summary of Observational Epidemiological Studies

      • Dilip K. Pandey, Noha Aljehani, Youji Soga

      Pages 17-37

   4. Blood Pressure Control and Primary Prevention of Stroke: Summary of Clinical Trial Data

      • William J. Elliott

      Pages 39-59

3. Mechanisms of Hypertension and Hypertension-Related Stroke

   1. Front Matter

      Pages 61-61

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   2. Mechanisms Underlying Essential Hypertension: Neurogenic and Non-neurogenic Contributors

      • Scott H. Carlson, Sean Stocker, J. Michael Wyss

      Pages 63-79

   3. The Effects of Hypertension and Stroke on the Cerebral Vasculature

      • Anne M. Dorrance

      Pages 81-108

   4. Pathophysiology and Mechanisms Whereby Hypertension May Cause Stroke

      • Beom Joon Kim, Hee-Joon Bae, Lawrence K. S. Wong

      Pages 109-128

4. Management of Blood Pressure for First Stroke Prevention, Immediately After Acute Stroke, and for Recurrent Stroke Prevention

   1. Front Matter

      Pages 129-129

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   2. Cardiovascular Risk Assessment, Summary of Guidelines for the Management of Hypertension and a Critical Appraisal of the 2014 Expert Panel of the National Institutes of Health Report

      • Luke J. Laffin, George L. Bakris

      Pages 131-150

   3. Acute Blood Pressure Management After Ischemic Stroke

      • J. Dedrick Jordan, William J. Powers

      Pages 151-162

   4. Hypertensive Encephalopathy, Posterior Reversible Encephalopathy Syndrome, and Eclampsia

      • Karen Orjuela, Sean D. Ruland

      Pages 163-178

   5. Acute Blood Pressure Management After Intracerebral Hemorrhage

      • Venkatesh Aiyagari

      Pages 179-196

   6. Blood Pressure Management in Subarachnoid Hemorrhage: The Role of Blood Pressure Manipulation in Prevention of Rebleeding and the Management of Vasospasm

      • Zakraus K. Mahdavi, Claudia A. Perez, Michael A. Rubin

      Pages 197-214

   7. Recurrent Stroke Prevention: Diuretic and Angiotensin-Converting Enzyme Inhibitors (ACEIs)—The PROGRESS Trial

      • Thomas K. A. Linden, Geoffrey A. Donnan

      Pages 215-231

   8. Blood Pressure Variability, Antihypertensive Therapy and Stroke Risk

      • Muhammad U. Farooq, Jiangyong Min, Lawrence K. S. Wong, Philip B. Gorelick

      Pages 233-244

   9. A Review of Antihypertensive Drugs and Choosing the Right Antihypertensive for Recurrent Stroke Prevention

      • Domenic A. Sica

      Pages 245-257

5. Mechanisms and Sequelae of Elevated Blood Pressure on Brain Function and Cognition

   1. Front Matter

      Pages 259-259

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   2. Vascular Cognitive Impairment and Alzheimer Disease: Are These Disorders Linked to Hypertension and Other Cardiovascular Risk Factors?

      • Fernando D. Testai, Philip B. Gorelick

      Pages 261-284

The second edition of this work continues to address the intimate pathophysiologic relationship between hypertension and stroke. The editors and authors clearly and concisely synthesize our developing knowledge of this relationship and place epidemiologic and physiologic information into a practical clinical context. Comprehensive chapters present the evidence supporting strategies for stroke prevention and care, including blood pressure lowering therapies, anti-coagulation, and management of other cerebrovascular risk factors. In addition to prescriptive measures for first stroke prevention, the book illuminates current regimens for care immediately after acute stroke and for the prevention of recurrent stroke. This latest edition also features extensively updated chapters from the previous edition, as well as new chapters on the effects of hypertension and stroke on the cerebral vasculature, blood pressure management in subarachnoid hemorrhage, and blood pressure variability, antihypertensive therapy, and stroke risk.

Written by experts in the field, Hypertension and Stroke: Pathophysiology and Management, Second Edition is of great utility for specialists in neurology and cardiovascular medicine and a valuable practical resource for all physicians caring for older adults and hypertensive patients.
 

• Blood pressure regulation
• Cerebral circulation
• Chronic kidney disease
• Hypertensive encephalopathy
• Ischemic Stroke
• Vascular cognitive impairment

• Departments of Neurological Surgery and Neurology and Neurotherapeutics , University of Texas Southwestern Medical Center , Dallas, USA

  Venkatesh Aiyagari

• Michigan State University Department of Translational Science & Molecular Medicine, Mercy Health Hauenstein Neurosciences, Grand Rapids, USA

  Philip B. Gorelick

Venkatesh Aiyagari, MBBS, DM
University of Texas Southwestern Medical Center, Departments of Neurological Surgery and Neurology and Neurotherapeutics, Dallas, TX, USA


Philip B. Gorelick, MD, MPH, FACP
Mercy Health Hauenstein Neuroscience Center, Michigan State University, College of Human Medicine, Grand Rapids, MI, USA 

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