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Trauma Induced Coagulopathy

  • Book
  • © 2016

Overview

Editors:
  1. Eduardo Gonzalez

    1. Dept of Surgery & Trauma Research Center, Univ of Colorado School of Medicine, Aurora, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Hunter B. Moore

    1. Dept of Surgery & Trauma Research Center, Univ of Colorado School of Medicine, Aurora, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  3. Ernest E. Moore

    1. Dept of Surgery & Trauma Research Center, Univ of Colorado Sch of Med&Denver Healt, Denver, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Outlines the current concepts that define trauma induced coagulopathy

  • Written by experts in the field

  • Provides a valuable source for quick reference to the clinician that is faced with specific clinical challenges when managing coagulopathy

  • Includes supplementary material: sn.pub/extras

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Table of contents (35 chapters)

  1. Front Matter

    Pages i-xxxi
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  2. Physiology of Hemostasis

    1. Front Matter

      Pages 1-1
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    2. Cell-Mediated Hemostasis

      • Maureane Hoffman
      Pages 3-14

    3. Thrombin-Antithrombin System

      • Susan C. Bock
      Pages 15-29

    4. Plasmin-Antiplasmin System

      • Nicola J. Mutch, Nuala A. Booth
      Pages 31-51

  3. Pathogenesis of Trauma Induced Coagulopathy

    1. Front Matter

      Pages 53-53
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    2. Thrombin Formation

      • Shekhar Kumar, Sriram Krishnaswamy
      Pages 55-74

    3. Fibrinogen

      • Eduardo Gonzalez, Ernest E. Moore, Hunter B. Moore
      Pages 75-90

    4. Activated Protein C

      • Benjamin M. Howard, Mitchell Jay Cohen
      Pages 91-114

    5. The Endothelium

      • Pär I. Johansson, Sisse R. Ostrowski
      Pages 115-124

    6. Platelets

      • Scott L. Diamond
      Pages 125-134

    7. Fibrinolysis

      • Hunter B. Moore, Ernest E. Moore, Eduardo Gonzalez
      Pages 135-147

    8. Neutrophils, Inflammation, and Innate Immunity in Trauma-Induced Coagulopathy

      • Christopher D. Barrett, Michael B. Yaffe
      Pages 149-165

    9. DAMPs: Damage-Associated Molecular Pattern Molecules in Hemostasis

      • Charles T. Esmon
      Pages 167-171

    10. The Complement System and Coagulation

      • Narcis I. Popescu, Florea Lupu
      Pages 173-193

    11. Disseminated Intravascular Coagulation

      • Satoshi Gando
      Pages 195-217

  4. Coagulation Assessment in Trauma Induced Coagulopathy

    1. Front Matter

      Pages 219-219
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    2. Prothrombin and Partial Thromboplastin Time

      • Ruchika Goel, Paul M. Ness
      Pages 221-226

    3. Fibrinogen Assays

      • Christoph J. Schlimp, Herbert Schöchl
      Pages 227-235

    4. Platelet Aggregometry

      • Taizo Nakano, Jorge Di Paola
      Pages 237-245
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Keywords

About this book

This text is aimed at defining the current concepts that define trauma induced coagulopathy by critically analyzing the most up-to-date studies from a clinical and basic science perspective. It will serve as a reference source for any clinician interested in reviewing the pathophysiology, diagnosis, and management of the coagulopathic trauma patient, and the data that supports it. By meticulously describing the methodology of most traditional as well as state of the art coagulation assays the reader will have full understanding of the tests that are used to study trauma induced coagulopathy. The evolving use of blood products as well as recently introduced hemostatic medications are reviewed in detail.

Trauma Induced Coagulopathy will also be a valuable source for quick reference to the clinician that is faced with specific clinical challenges when managing coagulopathy.

Reviews

“This is a collection of reviews describing the most important early complication of injury. … Senior trainees, basic scientists seeking clinical connection, and surgeons, particularly those in academic trauma practice, are an appropriate audience for this book from international authorities. … This is an important contribution that will guide senior clinicians and basic scientists seeking to better define this important clinical problem. The editors have been careful to assemble rigorous reviews that indicate the strengths and limitations of contemporary evidence.” (David J. Dries, Doody's Book Reviews, August, 2016)

Editors and Affiliations

  • Dept of Surgery & Trauma Research Center, Univ of Colorado School of Medicine, Aurora, USA

    Eduardo Gonzalez, Hunter B. Moore

  • Dept of Surgery & Trauma Research Center, Univ of Colorado Sch of Med&Denver Healt, Denver, USA

    Ernest E. Moore

About the editors

Ernest E. Moore, MD is Editor, Journal of Trauma and Acute Care Surgery (LWW)

Bibliographic Information

  • Book Title: Trauma Induced Coagulopathy

  • Editors: Eduardo Gonzalez, Hunter B. Moore, Ernest E. Moore

  • DOI: https://doi.org/10.1007/978-3-319-28308-1

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing Switzerland 2016

  • Softcover ISBN: 978-3-319-80322-7Published: 30 April 2018

  • eBook ISBN: 978-3-319-28308-1Published: 18 April 2016

  • Edition Number: 1

  • Number of Pages: XXXI, 601

  • Number of Illustrations: 44 b/w illustrations, 75 illustrations in colour

  • Topics: Traumatic Surgery, Intensive / Critical Care Medicine, General Surgery, Anesthesiology

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