Overview
- Focuses on the complexity of muscle as a whole tissue, and under both normal and abnormal states
- Provides up to date reviews of recent works in the field
- Written by international researchers at the cutting edge of the field of muscle biology
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 900)
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Table of contents (7 chapters)
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Front Matter
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Back Matter
Keywords
About this book
This book describes the diverse roles that growth factors and cytokines play in skeletal muscle. The extracellular environment has profound effects on the biology of skeletal muscle. The soluble portion of this environment includes a rich milieu of growth factors and cytokines which have been shown to regulate virtually all facets of the response of skeletal muscle to external stimuli, whether it be exercise induced metabolic shifts, remodeling in response to trauma or loading of the ongoing pathology associated with neuromuscular disease.
The chapters included in this work illustrate growth factors that directly affect skeletal muscle cells and those which influence non-muscle cells that contribute to the biology of skeletal muscle as a whole tissue. The current state of the art, with the advent of systems biology, allows for the delineation of signaling networks which are regulated by suites of growth factors. This is in stark contrast to early more traditional studies, which only examined the effects of isolated growth factors on the activity of skeletal muscle precursor cells in tissue culture.
The work presented in this volume ranges from reviewing and analyzing the roles of individual growth factors in detail, to the complex interplay of multiple soluble factors in the control of muscle functional, and dysfunctional states. The material covered in this volume will particularly suit readers from a range of research fields spanning general muscle biology and physiology, and those working on diseases and conditions affecting skeletal muscle both directly and indirectly.
Editors and Affiliations
Bibliographic Information
Book Title: Growth Factors and Cytokines in Skeletal Muscle Development, Growth, Regeneration and Disease
Editors: Jason White, Gayle Smythe
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-3-319-27511-6
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2016
Hardcover ISBN: 978-3-319-27509-3Published: 31 March 2016
Softcover ISBN: 978-3-319-80157-5Published: 25 April 2018
eBook ISBN: 978-3-319-27511-6Published: 22 March 2016
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: IX, 192
Number of Illustrations: 5 b/w illustrations, 14 illustrations in colour
Topics: Cytokines and Growth Factors, Human Physiology, Medical Biochemistry