Skip to main content
SpringerLink
Log in
SpringerLink
Log in

Tumor Microenvironment

Study Protocols

  • Conference proceedings
  • © 2016

Overview

Editors:
  1. Constantinos Koumenis

    1. Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Lisa M. Coussens

    1. Cell & Developmental Biology, Oregon Health & Science University, Portland, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  3. Amato Giaccia

    1. Department of Radiation Oncology, Stanford University School of Medic, Stanford, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  4. Ester Hammond

    1. Department of Oncology, University of Oxford, Oxford, United Kingdom

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Presents the proceedings of the 3rd International Conference on Tumor Microenvironment and Cellular Stress Evaluates novel targets for imaging or therapeutic intervention Discusses different cellular and animal models of tumor microenviornment study

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 899)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (16 papers)

  1. Front Matter

    Pages i-viii
    Download chapter PDF

  2. Staining Against Phospho-H2AX (γ-H2AX) as a Marker for DNA Damage and Genomic Instability in Cancer Tissues and Cells

    • Anika Nagelkerke, Paul N. Span
    Pages 1-10

  3. Measuring DNA Replication in Hypoxic Conditions

    • Iosifina P. Foskolou, Deborah Biasoli, Monica M. Olcina, Ester M. Hammond
    Pages 11-25

  4. Isolation of Proteins on Nascent DNA in Hypoxia and Reoxygenation Conditions

    • Monica M. Olcina, Amato J. Giaccia, Ester M. Hammond
    Pages 27-40

  5. In Vivo Interrogation of the Hypoxic Transcriptome of Solid Tumors: Optimizing Hypoxic Probe Labeling with Laser Capture Microdissection for Isolation of High-Quality RNA for Deep Sequencing Analysis

    • Lauren K. Brady, Vladimir Popov, Constantinos Koumenis
    Pages 41-58

  6. Gas Chromatography Coupled to Mass Spectrometry (GC–MS) to Study Metabolism in Cultured Cells

    • Fiona Grimm, Louise Fets, Dimitrios Anastasiou
    Pages 59-88

  7. Probing Cancer Cell Metabolism Using NMR Spectroscopy

    • Kate E. R. Hollinshead, Debbie S. Williams, Daniel A. Tennant, Christian Ludwig
    Pages 89-111

  8. Measuring the Impact of Microenvironmental Conditions on Mitochondrial Dehydrogenase Activity in Cultured Cells

    • Ramon C. Sun, Albert Koong, Amato Giaccia, Nicholas C. Denko
    Pages 113-120

  9. Measuring Autophagy in the Context of Cancer

    • Michael J. Morgan, Andrew Thorburn
    Pages 121-143

  10. Methods for Studying Autophagy Within the Tumor Microenvironment

    • Sengottuvelan Murugan, Ravi K. Amaravadi
    Pages 145-166

  11. Methods: Using Three-Dimensional Culture (Spheroids) as an In Vitro Model of Tumour Hypoxia

    • Russell Leek, David Robert Grimes, Adrian L. Harris, Alan McIntyre
    Pages 167-196

  12. Isolation of Glioma-Initiating Cells for Biological Study

    • Jing Hu, Geoffrey Markowitz, Xiao-Fan Wang
    Pages 197-209

  13. Isolation of Mouse and Human Tumor-Associated Macrophages

    • Luca Cassetta, Roy Noy, Agnieszka Swierczak, Gaël Sugano, Harriet Smith, Lisa Wiechmann et al.
    Pages 211-229

  14. Mouse Models of Brain Metastasis for Unravelling Tumour Progression

    • Manuel Sarmiento Soto, Nicola R. Sibson
    Pages 231-244

  15. Quantification of Lung Metastases from In Vivo Mouse Models

    • Joan Chang, Janine T. Erler
    Pages 245-251

  16. A Multimodal Data Analysis Approach for Targeted Drug Discovery Involving Topological Data Analysis (TDA)

    • Muthuraman Alagappan, Dadi Jiang, Nicholas Denko, Albert C. Koong
    Pages 253-268

  17. Efficient Protocol for the Identification of Hypoxic Cell Radiosensitisers

    • Cho Rong Hong, Jingli Wang, Kevin O. Hicks, Michael P. Hay
    Pages 269-290

  18. Back Matter

    Pages 291-297
    Download chapter PDF
Back to top

Keywords

About this book

This volume covers the topics presented at the 3rd International Conference on Tumor Microenvironment and Cellular Stress by an international community of researchers. The conference brings together scientists to discuss different cellular and animal models of tumor microenvironment study and identify common pathways that are candidates for therapeutic intervention; stimulate collaboration between groups that are more focused on elucidation of biochemical aspects of stress biology (e.g., HIF regulation) and groups that study the pathophysiological aspects of stress pathways or engaged in drug discovery; and critically evaluate novel targets for imaging or therapeutic intervention that would be of use to the tumor microenvironment community and pharmaceutical industry.

Editors and Affiliations

  • Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA

    Constantinos Koumenis

  • Cell & Developmental Biology, Oregon Health & Science University, Portland, USA

    Lisa M. Coussens

  • Department of Radiation Oncology, Stanford University School of Medic, Stanford, USA

    Amato Giaccia

  • Department of Oncology, University of Oxford, Oxford, United Kingdom

    Ester Hammond

Bibliographic Information

  • Book Title: Tumor Microenvironment

  • Book Subtitle: Study Protocols

  • Editors: Constantinos Koumenis, Lisa M. Coussens, Amato Giaccia, Ester Hammond

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-3-319-26666-4

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2016

  • Hardcover ISBN: 978-3-319-26664-0Published: 21 June 2016

  • Softcover ISBN: 978-3-319-79993-3Published: 30 May 2018

  • eBook ISBN: 978-3-319-26666-4Published: 20 June 2016

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: VIII, 297

  • Number of Illustrations: 21 b/w illustrations, 64 illustrations in colour

  • Topics: Cancer Research, Molecular Medicine, Immunology

Publish with us

Policies and ethics

Back to top

Search

Navigation