Editors:
- Comprehensive treatment of mass spectrometry, a tool at the forefront of bioanalysis that continues to grow
- The applications have wide appeal, from practitioners to public health professionals
- Contributions from a broad range of authors, encompassing all aspects of the field, will lend the volume a balanced and encyclopedic perspective?
- Includes supplementary material: sn.pub/extras
Buy it now
Buying options
Tax calculation will be finalised at checkout
Other ways to access
This is a preview of subscription content, log in via an institution to check for access.
Table of contents (13 chapters)
-
Front Matter
-
Methodology and Techniques
-
Front Matter
-
-
Subspecies Discrimination
-
Front Matter
-
-
Drug Resistance Monitoring and Assays
-
Front Matter
-
-
Back Matter
About this book
In the last quarter century, advances in mass spectrometry (MS) have been at the forefront of efforts to map complex biological systems including the human metabolome, proteome, and microbiome. All of these developments have allowed MS to become a well-established molecular level technology for microorganism characterization. MS has demonstrated its considerable advantage as a rapid, accurate, and cost-effective method for microorganism identification, compared to conventional phenotypic techniques. In the last several years, applications of MS for microorganism characterization in research, clinical microbiology, counter-bioterrorism, food safety, and environmental monitoring have been documented in thousands of publications. Regulatory bodies in Europe, the US, and elsewhere have approved MS-based assays for infectious disease diagnostics. As of mid-2015, more than 3300 commercial MS systems for microorganism identification have been deployed worldwide in hospitals and clinical labs.
While previous work has covered broader approaches in using MS to characterize microorganisms at the species level or above, this book focuses on strain-level and subtyping applications. In twelve individual chapters, innovators, leaders and practitioners in the field from around the world have contributed to a comprehensive overview of current and next-generation approaches for MS-based microbial characterization at the subspecies and strain levels. Chapters include up-to-date reference lists as well as web-links to databases, recommended software, and other useful tools.The emergence of new, antibiotic-resistant strains of human or animal pathogens is of extraordinary concern not only to the scientific and medical communities, but to the general public as well. Developments of novel MS-based assays for rapid identification of strains of antibiotic-resistant microorganisms are reviewed in the book as well. Microbiologists, bioanalytical scientists, infectious disease specialists, clinical laboratory and public health practitioners as well as researchers in universities, hospitals, government labs, and the pharmaceutical and biotechnology industries will find this book to be a timely and valuable resource.Â
Editors and Affiliations
-
Johns Hopkins University, Applied Physics Laboratory, Laurel, USA
Plamen Demirev
-
Arizona State University, School of Math and Natural Sciences, Phoenix, USA
Todd R. Sandrin
About the editors
Todd Sandrin, School of Mathematical and Natural Sciences, Arizona State University
Bibliographic Information
Book Title: Applications of Mass Spectrometry in Microbiology
Book Subtitle: From Strain Characterization to Rapid Screening for Antibiotic Resistance
Editors: Plamen Demirev, Todd R. Sandrin
DOI: https://doi.org/10.1007/978-3-319-26070-9
Publisher: Springer Cham
eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)
Copyright Information: Springer International Publishing Switzerland 2016
Hardcover ISBN: 978-3-319-26068-6Published: 19 January 2016
Softcover ISBN: 978-3-319-79888-2Published: 30 March 2018
eBook ISBN: 978-3-319-26070-9Published: 12 January 2016
Edition Number: 1
Number of Pages: VIII, 336
Number of Illustrations: 32 b/w illustrations, 36 illustrations in colour
Topics: Mass Spectrometry, Applied Microbiology, Epidemiology, Drug Resistance