Implantable Medical Electronics

1. Front Matter

   Pages i-xxxiii

   PDF

2. Introduction, Scope, and Overview

   • Vinod Kumar Khanna

   Pages 1-9

3. Basic Concepts and Principles

   1. Front Matter

      Pages 11-11

      PDF

   2. Diagnostic and Therapeutic Roles of Implantable Devices in the Human Electrical Machine: A Quick Primer

      • Vinod Kumar Khanna

      Pages 13-29

   3. Generic Implant Architecture and Organization

      • Vinod Kumar Khanna

      Pages 31-54

   4. Dilemmas and Enigmas of Implantable IC Design

      • Vinod Kumar Khanna

      Pages 55-79

   5. Neural Stimulation and Charge Balancing Approaches

      • Vinod Kumar Khanna

      Pages 81-107

   6. Implant Clocking and Timing Circuits

      • Vinod Kumar Khanna

      Pages 109-133

   7. Electrostimulation Pulse Generators

      • Vinod Kumar Khanna

      Pages 135-151

   8. Biomaterials for Implants

      • Vinod Kumar Khanna

      Pages 153-166

   9. Batteries for Implants

      • Vinod Kumar Khanna

      Pages 167-183

   10. Wireless Communications and Powering of Implants

       • Vinod Kumar Khanna

       Pages 185-207

   11. Cyber Security and Confidentiality Concerns with Implants

       • Vinod Kumar Khanna

       Pages 209-225

4. Applications

   1. Front Matter

      Pages 227-227

      PDF

   2. Neural Amplifier Circuits in Implants

      • Vinod Kumar Khanna

      Pages 229-247

   3. Implantable Sensors

      • Vinod Kumar Khanna

      Pages 249-265

   4. Cardiac Pacemakers

      • Vinod Kumar Khanna

      Pages 267-292

   5. Implantable Cardioverter Defibrillators

      • Vinod Kumar Khanna

      Pages 293-307

   6. Deep Brain Stimulation

      • Vinod Kumar Khanna

      Pages 309-329

   7. Epidural Spinal Cord Stimulation

      • Vinod Kumar Khanna

      Pages 331-340

This book is a comprehensive, interdisciplinary resource for the latest information on implantable medical devices, and is intended for graduate students studying electrical engineering, electronic instrumentation, and biomedical engineering. It is also appropriate for academic researchers, professional engineers, practicing doctors, and paramedical staff. Divided into two sections on Basic Concepts and Principles, and Applications, the first section provides an all-embracing perspective of the electronics background necessary for this work. The second section deals with pacing techniques used for the heart, brain, spinal cord, and the network of nerves that interlink the brain and spinal cord with the major organs, including ear and eye prostheses.

The four main offshoots of implantable electronics, which this book discusses, are:

• The insertion of an implantable neural amplifier for accurate recording of neural signals for neuroengineering studies
  
• The use of implantable pulse generators for pacing the activities of diseased organs
• The use of implantable sensors for observing the influence of therapy and monitoring a patient’s biological parameters
• The use of drug delivery systems to supervise the supply of accurate doses of medicine to affected parts

Readers will also find chapters on the ess
entials of clocking and timing circuits, pulse generator circuits, neural amplifiers, batteries, biomaterials and biocompatibility, and more. Unique to this book is also a chapter on cyber security and confidentiality concerns with implants. End-of-chapter questions and exercises help readers apply the content to practical use, making this an ideal book for anyone wishing to learn more about implantable devices.

• Bio-MEMS
• Cochlear and Opthalmic Implants
• Immunoisolation
• Implantable Drug Delivery Devices
• Implantable Electronics
• Medical Electronics
• Micropumps
• Nanoparticles
• Neurostimulators
• pharmacotherapy

• MEMS & Microsensors Group, CSIR-Central Electronics Engineering Research Institute, Pilani, India

  Vinod Kumar Khanna

Vinod Kumar Khanna received the Ph.D. degree in physics from Kurukshetra University, Kurukshetra (Haryana), India, in 1988. From 1977 to 1979, he was a Research Assistant with the Physics Department, Lucknow University. He joined the solid-state devices division of Council of Scientific and Industrial Research (CSIR)–Central Electronics Engineering Research Institute (CEERI), Pilani in April, 1980. During his tenure of more than 34 years of service at CSIR-CEERI, he worked on various research and development projects on thin-film aluminum oxide humidity sensor, power semiconductor devices (high-current and high-voltage rectifier, high-voltage TV deflection transistor, power Darlington transistor, fast switching thyristor, power DMOSFET and IGBT), PIN diode neutron dosimeter and PMOSFET gamma ray dosimeter, ion-sensitive field-effect transistor (ISFET), microheater-embedded gas sensor, capacitive MEMS ultrasonic transducer, and other MEMS devices. He superannuated in November 2014 as Chief Scientist & Head, MEMS & Microsensors Group, and Professor, AcSIR (Academy of Scientific & Innovative Research). Presently, he is working as an Emeritus Scientist, CSIR and Emeritus Professor, AcSIR. His research interests are micro- and nanosensors, and power semiconductor devices. He is a fellow of the Institution of Electronics & Telecommunication Engineers (IETE), India. He is a life member of Indian Physics Association (IPA), Semiconductor Society (India), and Indo-French Technical Association (IFTA).

Dr. Khanna has published 8 previous books, 6 chapters in edited books, and 175 research papers in national/international journals and conference proceedings; he holds two US and two Indian patents.

Policies and ethics