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  • © 2016

Hepatic De Novo Lipogenesis and Regulation of Metabolism

Editors:

  • Expert contributors offer all the primary and relevant metabolic information the reader needs to review to understand the complex and diverse role of the liver in metabolism

  • Discusses dietary nutrients and the effect they have on the epigenetic regulation of genes

  • Covers the many studies that have unmasked the important roles that proteins expressed in the liver play in the development of or protection from metabolic diseases

  • Includes supplementary material: sn.pub/extras

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-xi
  2. Molecular Mechanisms of Lipotoxicity in Nonalcoholic Fatty Liver Disease

    • Sophie C. Cazanave, Arun J. Sanyal
    Pages 101-129
  3. Role of Lipogenesis and Lipid Desaturases in Non-alcoholic Fatty Liver Disease

    • Mohamed Amine Lounis, Sabri Rial, James M. Ntambi, Catherine Mounier
    Pages 143-164
  4. Lipid Droplet Proteins and Hepatic Lipid Metabolism

    • Yumi Imai, Michelle B. Trevino, Rexford S. Ahima
    Pages 165-188
  5. Influence of Gut Microbiota on Hepatic Lipogenesis and Disease Pathogenesis

    • Vishal Singh, Beng San Yeoh, James M. Ntambi, Matam Vijay-Kumar
    Pages 189-209
  6. Hepatic Lipogenesis: Nutritional Control and Pathophysiological Relevance

    • Shih-Lung Woo, Ting Guo, Chaodong Wu
    Pages 211-234
  7. Metabolic Rhythm of Hepatic Lipogenesis: Regulation and Roles in Metabolism

    • David Jacobi, Hyunjii J. Cho, Ryan K. Alexander, Chih-Hao Lee
    Pages 235-253
  8. Adipose Tissue DNL and Its Role in Metabolic Homeostasis

    • Ludger Scheja, Christoph Buettner
    Pages 267-283
  9. The Lipogenic Effect of Insulin Revisited

    • Sonia M. Najjar
    Pages 285-295
  10. Back Matter

    Pages 297-305

About this book

The liver is the largest solid vital organ in mammals that supports other organ in the body in some facet.  This book synthesizes all the primary and relevant metabolic information that one needs to review to understand the complex and diverse role of the liver in metabolism.

With the current epidemic of metabolic diseases, it is of immediate importance to understand the contribution of the liver in health and its role in the development of impaired metabolic regulation. This book covers the many studies that have unmasked important roles that proteins expressed in the liver play in the development of or protection from metabolic diseases.

One of the major metabolic functions of the liver is to carry out de novo lipogenesis, which is the metabolic pathway that allows the conversion of excess carbohydrates into fatty acids. The process of de novo lipogenesis is covered in depth within this volume.  The book is an important contribution to the vast literature and ongoing research on liver function.

Editors and Affiliations

  • Departments of Biochemistry and Nutritional Sciences, University of Wisconsin-Madison, Madison, USA

    James M. Ntambi

About the editor

James M. Ntambi, PhD, is the Katherine Berns Von Donk Steenbock Professor in Nutrition, Department of Chemistry, College of Agricultural and Life Sciences, at the University of Wisconsin, Madison.

Bibliographic Information

  • Book Title: Hepatic De Novo Lipogenesis and Regulation of Metabolism

  • Editors: James M. Ntambi

  • DOI: https://doi.org/10.1007/978-3-319-25065-6

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing Switzerland 2016

  • Hardcover ISBN: 978-3-319-25063-2Published: 29 December 2015

  • Softcover ISBN: 978-3-319-79728-1Published: 30 March 2019

  • eBook ISBN: 978-3-319-25065-6Published: 17 December 2015

  • Edition Number: 1

  • Number of Pages: XI, 305

  • Number of Illustrations: 30 b/w illustrations, 5 illustrations in colour

  • Topics: Biochemistry, general, Metabolic Diseases, Hepatology, Diabetes, Nutrition

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access