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Connective Tissue Disease

A Comprehensive Guide - Volume 1

  • Presents the latest research findings and treatment trends for SLE and Sjögren syndrome
  • Covers both basic science and clinical medicine
  • Discusses “treat to target” interventions
  • Highlights key points for ease of reference

Part of the book series: Rare Diseases of the Immune System (RDIS)

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Table of contents (28 chapters)

  1. Front Matter

    Pages i-vii
  2. Systemic Lupus Erythematosus

    1. Front Matter

      Pages 1-1
    2. Introduction

      • Dario Roccatello
      Pages 3-4
    3. Epidemiology of Systemic Lupus Erythematosus

      • Simone Baldovino, Cristiana Rollino
      Pages 5-21
    4. SLE Pathogenesis: From Apoptosis to Lymphocyte Activation

      • Danilo Squatrito, Giacomo Emmi, Elena Silvestri, Domenico Prisco, Lorenzo Emmi
      Pages 23-34
    5. Systemic Lupus Erythematosus: Clinical Aspects

      • Savino Sciascia, Maria Josè Cuadrado
      Pages 35-45
    6. Autoantibodies and Biomarkers: Diagnostic Aspects

      • Savino Sciascia, Maria Laura Bertolaccini
      Pages 47-59
    7. Joint Involvement in Systemic Lupus Erythematosus

      • Daniela Rossi, Vittorio Modena, G. Bianchi, Raffaele Pellerito, Dario Roccatello
      Pages 61-76
    8. Lupus Nephritis

      • Antonello Pani, Andrea Angioi, Franco Ferrario
      Pages 95-112
    9. Neuropsychiatric Systemic Lupus Erythematosus

      • Karen Schreiber, Soren Jacobsen
      Pages 113-131
    10. Cardiovascular Issues in SLE

      • Maria Gerosa, Mara Taraborelli, Pier Luigi Meroni, Angela Tincani
      Pages 133-145
    11. Systemic Lupus Erythematosus and Pregnancy

      • Paula Alba, Munther Khamashta
      Pages 147-158
    12. Vitamin D, Autoimmune Diseases, and Systemic Lupus Erythematosus

      • Sabrina Paolino, Vanessa Smith, Carmen Pizzorni, Bruno Seriolo, Alberto Sulli, Maurizio Cutolo
      Pages 159-168
    13. The Impact of aPL Detection on Pregnancy

      • Maria Tiziana Bertero, Anna Kuzenko, Mario Bazzan
      Pages 169-181
    14. Systemic Lupus Erythematosus and Antiphospholipid Syndrome

      • Jose A. Gómez-Puerta, Ricard Cervera
      Pages 183-198
    15. Disease Activity Indices and Prognosis of Systemic Lupus Erythematosus

      • Luca Iaccarino, Maddalena Larosa, Andrea Doria
      Pages 199-211
    16. Conventional Treatment of Systemic Lupus Erythematosus

      • Giacomo Quattrocchio, Fernando Fervenza, Dario Roccatello
      Pages 213-238
    17. Innovative Therapies in Systemic Lupus Erythematosus

      • Roberta Fenoglio, Fernando Fervenza, Dario Roccatello
      Pages 239-261
    18. SLE in 21st Century

      • Graham Hughes
      Pages 263-264

About this book

In this volume devoted to systemic lupus erythematosus (SLE) and Sjögren syndrome, leading specialists from different disciplines present the latest research findings on many aspects of the diseases and describe the most recent trends in treatment, such as the “treat to target” approach. Both basic science and clinical medicine are addressed, with emphasis on the most promising clinical and laboratory-based studies. The coverage is comprehensive in scope, encompassing, for example, epidemiology, pathogenesis, autoantibodies and biomarkers, disease manifestations, involvement of different organs or systems, relationships with other disorders, biological therapy of SLE, and systemic treatment of Sjögren syndrome. Readers will find this first volume of Connective Tissue Disease to be an excellent source of information on the current understanding of, and clinical approach to, SLE and Sjögren syndrome that clearly conveys the progress made in recent years.

Editors and Affiliations

  • Giovanni Bosco Hospital, Center of Immunopathology/Rare Dise, Torino, Italy

    Dario Roccatello

  • University of Florence, Florence, Italy

    Lorenzo Emmi

About the editors

Dario Roccatello is Full Professor of Clinical Pathology at the University of Turin and Director of the Center of Research on Immunopathology and Rare Diseases (CMID), San Giovanni Bosco Hospital, Turin. He is also Director of the Interregional Coordination Center of Rare Diseases for Piedmont and Aosta Valley, and Director of the 2nd level 2-year Master on Rare Diseases at Turin Med. School. He specialized in nephrology and nuclear medicine, and is presently interested in molecular medicine,  specifically in the field of Realtime PCR. Prof. Roccatello has been visiting fellow at the Royal Adelaide Hospital, Adelaide (Australia) lead a Research Collaboration with the Pathology Department Brown University of Providence, Rhode Island, USA, was visitor Investigator at the Department of Immunology and Allergic Diseases, National Institute of Health, Bethesda, USA and Attaché Associé Scientifique at the Centre Hospitalier Régional Universitaire of Grenoble (France). He has authored 400 scientific articles, 118 of which published in Peer-reviewed International Journals, in the fields of nephrology, clinical immunology and laboratory medicine.

Lorenzo Emmi is Head of the Reference Center for Systemic Autoimmune Diseases, at AOU Careggi Hospital, Florence, and Full Professor of immunoallergology in several medical schools at Florence University. He is author of many articles in international peer-reviewed journals and author/editor of volumes related to his field of activity. He has lead a group of rheumatologists in the preparation of Regional guidelines on systemic autoimmune diseases and is currently in charge, as head of the Center for Autoimmune Diseases, of establishing a regional network on allergologic diseases for the Tuscany region. Dr. Emmi is series editor with Professor Domenico Prisco.

Bibliographic Information

  • Book Title: Connective Tissue Disease

  • Book Subtitle: A Comprehensive Guide - Volume 1

  • Editors: Dario Roccatello, Lorenzo Emmi

  • Series Title: Rare Diseases of the Immune System

  • DOI: https://doi.org/10.1007/978-3-319-24535-5

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing Switzerland 2016

  • Hardcover ISBN: 978-3-319-24533-1Published: 18 April 2016

  • Softcover ISBN: 978-3-319-79642-0Published: 22 April 2018

  • eBook ISBN: 978-3-319-24535-5Published: 09 April 2016

  • Series ISSN: 2282-6505

  • Series E-ISSN: 2283-6403

  • Edition Number: 1

  • Number of Pages: VII, 406

  • Number of Illustrations: 11 b/w illustrations, 20 illustrations in colour

  • Topics: Rheumatology, Antibodies, Nephrology

Buy it now

Buying options

eBook USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 179.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access