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Natural Killer Cells

  • Book
  • © 2016

Overview

Editors:
  1. Eric Vivier

    1. Assistance Publique des Hôpitaux de Marseille, Marseille 05, France and Centre d'Immunologie de Marseille-Luminy, Aix Marseille Université - INSERM - CNRS, Marseille 09, France

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  2. James Di Santo

    1. INSERM U 668, Pasteur Institute, Paris, France

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  3. Alessandro Moretta

    1. University of Genoa, Genova, Italy

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  • Broadens the understanding of NK antiviral functions
  • Reviews exhaustively the key recent research into tumor control by NK cells
  • Enriches understanding of NK cell education and homeostasis
  • Includes supplementary material: sn.pub/extras

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 395)

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-viii
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  2. Transcriptional Control of NK Cells

    • Joseph C. Sun
    Pages 1-36

  3. Development, Homeostasis, and Heterogeneity of NK Cells and ILC1

    • Cyril Seillet, Gabrielle T. Belz, Nicholas D. Huntington
    Pages 37-61

  4. Diversification and Functional Specialization of Human NK Cell Subsets

    • Frank Cichocki, Heinrich Schlums, Jakob Theorell, Bianca Tesi, Jeffrey S. Miller, Hans-Gustaf Ljunggren et al.
    Pages 63-93

  5. Dynamic Regulation of NK Cell Responsiveness

    • Nadir Kadri, Arnika Kathleen Wagner, Sridharan Ganesan, Klas Kärre, Stina Wickström, Maria H. Johansson et al.
    Pages 95-114

  6. NK Cells and Cancer Immunoediting

    • Camille Guillerey, Mark J. Smyth
    Pages 115-145

  7. Sweet Is the Memory of Past Troubles: NK Cells Remember

    • Deborah W. Hendricks, Gundula Min-Oo, Lewis L. Lanier
    Pages 147-171

  8. Lessons from NK Cell Deficiencies in the Mouse

    • Florence Deauvieau, Aurore Fenis, François Dalençon, Nicolas Burdin, Eric Vivier, Yann Kerdiles
    Pages 173-190

  9. Probing Human NK Cell Biology Using Human Immune System (HIS) Mice

    • Yan Li, James P. Di Santo
    Pages 191-208

  10. Haploidentical Haematopoietic Stem Cell Transplantation: Role of NK Cells and Effect of Cytomegalovirus Infections

    • Mariella Della Chiesa, Lorenzo Moretta, Letizia Muccio, Alice Bertaina, Francesca Moretta, Franco Locatelli et al.
    Pages 209-224

  11. The Past, Present, and Future of NK Cells in Hematopoietic Cell Transplantation and Adoptive Transfer

    • Frank Cichocki, Michael R. Verneris, Sarah Cooley, Veronika Bachanova, Claudio G. Brunstein, Bruce R. Blazar et al.
    Pages 225-243

  12. Back Matter

    Pages 245-247
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Keywords

About this book

To celebrate the 40th anniversary of the discovery of Natural Killer (NK) cells, this volume focuses on the recent advances in our understanding of NK cell development and differentiation and their acquisition of functional properties, as well as the latest models for NK-cell analysis in mice and applications in clinical medicine. NK cells have travelled a circuitous path from their initial description as ‘spontaneous killers’ (for some simply an experimental artifact) to being a bona fide subset of innate lymphoid cells with a complementary mode of action in immune defense and an important mediator of immune reactivity in health and disease. Together, these reviews provide a timely and concise picture of the evolution of NK cells as essential agents in immunity and as potent weapons against disease. This book offers an appealing and insightful resource for scientists and clinicians.

Editors and Affiliations

  • Assistance Publique des Hôpitaux de Marseille, Marseille 05, France and Centre d'Immunologie de Marseille-Luminy, Aix Marseille Université - INSERM - CNRS, Marseille 09, France

    Eric Vivier

  • INSERM U 668, Pasteur Institute, Paris, France

    James Di Santo

  • University of Genoa, Genova, Italy

    Alessandro Moretta

About the editors

Prof. Eric Vivier, Centre d'Immunologie de Marseille-Luminy, Marseille, France Prof. James Di Santo, Innate Immunity Unit, Institut Pasteur, Paris, France Prof. Alessandro Moretta, Experimental Medicine at Genoa University, Genoa, Italy

Bibliographic Information

  • Book Title: Natural Killer Cells

  • Editors: Eric Vivier, James Di Santo, Alessandro Moretta

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-319-23916-3

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2016

  • Hardcover ISBN: 978-3-319-23915-6Published: 26 February 2016

  • Softcover ISBN: 978-3-319-79554-6Published: 14 March 2019

  • eBook ISBN: 978-3-319-23916-3Published: 15 February 2016

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: VIII, 247

  • Topics: Immunology, Virology, Cancer Research

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