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Cancer Vaccines

  • Book
  • © 2017

Overview

Editors:
  1. Natalia Savelyeva

    1. Faculty of Medicine, Cancer Sciences Unit, University of Southampton, Southhampton, United Kingdom

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    You can also search for this editor in PubMed   Google Scholar

  2. Christian Ottensmeier

    1. Faculty of Medicine, Cancer Sciences Unit, University of Southampton , Southampton, United Kingdom

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Reviews novel approaches in the pre-clinical development of novel cancer vaccines
  • Summarizes the results of recent clinical evaluation
  • Describes new technologies and new cancer treatments
  • Includes supplementary material: sn.pub/extras

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 405)

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Table of contents (8 chapters)

  1. Front Matter

    Pages i-vii
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  2. New Approaches in Immunotherapy for the Treatment of Lung Cancer

    • Sonia Quaratino, Ulf Forssmann, Jens-Peter Marschner
    Pages 1-31

  3. Novel Approaches for Vaccination Against HPV-Induced Cancers

    • Emma King, Christian Ottensmeier, Kevin G. J. Pollock
    Pages 33-53

  4. Tapping the Potential of DNA Delivery with Electroporation for Cancer Immunotherapy

    • Kimberly A. Kraynyak, Angela Bodles-Brakhop, Mark Bagarazzi
    Pages 55-78

  5. Targeted Immunotherapy Designed to Treat MUC1-Expressing Solid Tumour

    • Bruce Acres, Gisele Lacoste, Jean-Marc Limacher
    Pages 79-97

  6. Chimeric DNA Vaccines: An Effective Way to Overcome Immune Tolerance

    • Federica Riccardo, Elisabetta Bolli, Marco Macagno, Maddalena Arigoni, Federica Cavallo, Elena Quaglino
    Pages 99-122

  7. Linked CD4 T Cell Help: Broadening Immune Attack Against Cancer by Vaccination

    • Natalia Savelyeva, Alex Allen, Warayut Chotprakaikiat, Elena Harden, Jantipa Jobsri, Rosemary Godeseth et al.
    Pages 123-143

  8. mRNA Cancer Vaccines—Messages that Prevail

    • Christian Grunwitz, Lena M. Kranz
    Pages 145-164

  9. The Use of Anti-CD40 mAb in Cancer

    • Marcus Remer, Ann White, Martin Glennie, Aymen Al-Shamkhani, Peter Johnson
    Pages 165-207

  10. Back Matter

    Pages 209-210
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Keywords

About this book

This volume focuses on the laboratory and clinical experience with targeting viral onco-antigens, while also reviewing the approaches to targeting self-cancer antigens in cancers of non-viral origin, where self-tolerance has been a challenge. It emphasizes the importance of selecting the right vaccine platform to induce a successful immune response against cancer antigens. In addition, the volume discusses the advances made with genetic vaccines, including recent advances with  DNA vaccines and the rapid transition of mRNA vaccines from the laboratory to bedside. The new avenues opening up for cancer immunotherapy underline the importance of combinational approaches using cancer vaccines with costimulatory antibodies, which may dramatically improve cancer treatment.
This book is intended for all translational researchers and clinicians who aspire to develop novel vaccination approaches for cancer patients with unmet clinical needs.

Editors and Affiliations

  • Faculty of Medicine, Cancer Sciences Unit, University of Southampton, Southhampton, United Kingdom

    Natalia Savelyeva

  • Faculty of Medicine, Cancer Sciences Unit, University of Southampton , Southampton, United Kingdom

    Christian Ottensmeier

About the editors

Dr. Natalia Savelyeva is a lecturer in cancer immunology in Southhampton Dr. Christian Ottensmeier is a professor of experimental medicine in Southhampton

Bibliographic Information

  • Book Title: Cancer Vaccines

  • Editors: Natalia Savelyeva, Christian Ottensmeier

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-319-23910-1

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2017

  • Hardcover ISBN: 978-3-319-23909-5Published: 18 July 2017

  • Softcover ISBN: 978-3-319-79552-2Published: 28 July 2018

  • eBook ISBN: 978-3-319-23910-1Published: 10 July 2017

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: VII, 210

  • Topics: Cancer Research, Immunology, Vaccine

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