The Duration and Safety of Osteoporosis Treatment

Providing a comprehensive review of short-and long-term adverse events of both antiresorptive and anabolic drugs, this practical guide updates the clinician on the pathophysiology of osteoporosis and the principles behind our present and future pharmaceuticals. Leading practitioners in the field examine all current literature and data regarding the duration and safety of these therapies, with recommendations for clinicians on decision-making and best practices for osteoporosis patients. An overview of the pathophysiology and epidemiology of osteoporosis and discussion of both anabolic and antiresorptive drugs is followed by fracture risk assessment and an examination of treatment failures. Next, a number of chapters are dedicated to the diagnosis, presentation and management of atypical femur fractures and osteonecrosis of the jaw (ONJ), each of which are significant patient concerns when using these osteoporosis treatments. The introduction and utilization of drug holidays is also discussed, as well as the long-term outlook for management of osteoporotic patients. Written and edited by experts in the field, The Duration and Safety of Osteoporosis Treatment is a balanced resource for researchers, practitioners and policy-makers alike for clinical decision-making and patient care. 

• Anabolic therapy
• Antiresorptive therapy
• Atypical femur fracture
• Bisphosphonates
• Bone microarchitecture
• Drug holiday
• Fracture risk assessment
• Osteonecrosis of the jaw
• Osteoporosis treatment

• Division of Rheumatology, Department of Medicine, Cedars-Sinai Medical Center; University of California Los Angeles, David Geffen School of Medicine, Los Angeles, USA

  Stuart Silverman

• Institute of Clinical Research; Department of Medicine, Holbæk, Denmark, University of Southern Denmark, Odense Patient Data Explorative Network; Holbæk Hospital, Odense, Denmark

  Bo Abrahamsen

Stuart L. Silverman, MD, FACP, FACR

Cedars-Sinai Medical Center

Division of Rheumatology

Department of Medicine

Los Angeles, CA, USA

University of California Los Angeles

David Geffen School of Medicine

Los Angeles, CA, USA

Bo Abrahamsen, MD, PhD

University of Southern Denmark

Odense Patient Data Explorative Network

Institute of Clinical Research

Odense, Denmark

Holbæk Hospital

Department of Medicine
Holbæk, Denmark

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