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Advances in Geroscience

  • Book
  • © 2016

Overview

  • Provides a comprehensive overview of the new discipline, geroscience
  • Examines mechanisms and consequences of aging as the main risk factor for most chronic diseases
  • Provides links between aging biology and age-related diseases
  • Provides specific coverage on a wide range of chronic diseases, from both basic and clinical perspectives

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Table of contents (19 chapters)

Keywords

About this book

This book provides the first comprehensive overview of a new scientific discipline termed Geroscience. Geroscience examines the molecular and cellular mechanisms that might explain why aging is the main risk factor for most chronic diseases affecting the elderly population. Over the past few decades, researchers have made impressive progress in understanding the genetics, biology and physiology of aging. This book presents vital research that can help readers to better understand how aging is a critical malleable risk factor in most chronic diseases, which, in turn, could lead to interventions that can help increase a healthy lifespan, or ‘healthspan.’

The book begins with an analysis of the Geroscience hypothesis, as well as the epidemiological underpinnings that define aging as a candidate main risk factor for most chronic diseases. Next, each chapter focuses on one particular disease, or group of diseases, with an emphasis on how basic molecular and cellular biology might explain why aging is a major risk factor for it. Coverage in the book includes: cancer, cardiovascular disease, dementias, stroke, Parkinson's and Alzheimer’s diseases, osteoporosis, arthritis, diabetes asthma, emphysema, kidney disease, vision impairment, and AIDS/HIV.  It finishes with a chapter on pain in the elderly and an overview of future steps needed to bring the newly acquired knowledge into the clinic and the public at large.

Editors and Affiliations

  • National Inst. of Aging Division of Aging Biology, National Institutes of Health, Bethesda, USA

    Felipe Sierra

  • National Inst on Aging/ National Inst of Health, Division of Aging Biology, Bethesda, USA

    Ronald Kohanski

Bibliographic Information

  • Book Title: Advances in Geroscience

  • Editors: Felipe Sierra, Ronald Kohanski

  • DOI: https://doi.org/10.1007/978-3-319-23246-1

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing 2016

  • Hardcover ISBN: 978-3-319-23245-4Published: 20 November 2015

  • Softcover ISBN: 978-3-319-36194-9Published: 23 August 2016

  • eBook ISBN: 978-3-319-23246-1Published: 10 November 2015

  • Edition Number: 1

  • Number of Pages: XXIII, 622

  • Number of Illustrations: 39 b/w illustrations

  • Topics: Geriatrics/Gerontology, Molecular Medicine, Aging

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