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  • © 2016

Biologics to Treat Substance Use Disorders

Vaccines, Monoclonal Antibodies, and Enzymes

Editors:

  • Covers all aspects of vaccines and other biologics employed for treatment of substance use disorders

  • Discusses novel strategies to optimize the development and efficacy of biologics

  • Written and edited by experts in the field

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Softcover Book USD 139.99
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Hardcover Book USD 109.99
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Table of contents (21 chapters)

  1. Front Matter

    Pages i-xvi
  2. Vaccines

    1. Front Matter

      Pages 5-5
    2. Vaccines for Treating Cocaine Use Disorders

      • Coreen B. Domingo, Daryl Shorter, Thomas R. Kosten
      Pages 25-36
    3. Vaccines for Opioid Addiction

      • Michael D. Raleigh, Paul R. Pentel
      Pages 37-63
    4. Vaccines for Methamphetamine Use Disorder

      • Thomas R. Kosten, Therese A. Kosten
      Pages 65-74
    5. Cocaine and HIV Infection

      • Timothy Cardozo, Sergey V. Shmelkov, Kenneth Carr, John Rotrosen, Pedro Mateu-Gelabert, Samuel R. Friedman
      Pages 75-103
  3. Monoclonal Antibodies

    1. Front Matter

      Pages 105-105
    2. Monoclonal Antibodies

      • S. Michael Owens
      Pages 107-108
    3. Anti-cocaine Monoclonal Antibodies

      • Hanna N. Wetzel, William J. Ball, Andrew B. Norman
      Pages 109-117
    4. Discovery and Development of an Anti-methamphetamine Monoclonal Antibody for Use in Treating Methamphetamine Abuse

      • Michael D. Hambuchen, Misty W. Stevens, Melinda G. Gunnell, W. Brooks Gentry, S. Michael Owens
      Pages 119-142
  4. Enzymes

    1. Front Matter

      Pages 143-143
    2. Viral Gene Transfer of Enzymes

      • W. Stephen Brimijoin
      Pages 167-185
    3. Cocaine Hydrolases Designed from Butyrylcholinesterase

      • Fang Zheng, Chang-Guo Zhan
      Pages 187-225
  5. Strategies to Optimize the Development of Biologics to Treat Addictions

    1. Front Matter

      Pages 227-227
    2. Adenovirus-Based Vaccines for the Treatment of Substance Use Disorders

      • David F. Havlicek, Jonathan B. Rosenberg, Dolan Sondhi, Ronald G. Crystal, Stephen M. Kaminsky
      Pages 229-248
    3. Nanoparticle-Based Nicotine Vaccine

      • Petr O. Ilyinskii, Lloyd P. M. Johnston
      Pages 249-278
    4. Exploration of DNA Nanostructures for Rational Design of Vaccines

      • Xiaowei Liu, Sidney M. Hecht, Hao Yan, Paul R. Pentel, Yung Chang
      Pages 279-293

About this book

This book is a scientific compendium documenting the state of the art in the discovery and development of vaccines, monoclonal antibodies, and enzymes for the treatment of Substance Use Disorders (SUDs). The book gives detailed consideration to some of the most cutting edge topics in addiction medicine, including vaccines for nicotine, cocaine, heroin, and methamphetamine dependence; monoclonal antibodies against cocaine, methamphetamine, and phencyclidine; and the enzymes butyrylcholinesterase and cocaine esterase. In addition, the text covers a wide range of new strategies designed to optimize the development and efficacy of biologics. Unlike any other resource, this book reviews how biologics offer exciting new therapeutic opportunities for various psychiatric conditions.

Written by experts in the field, Biologics to Treat Substance Use Disorders is as an authoritative reference for psychiatrists, psychologists, and all other medical professionals working with patients suffering from Substance Use Disorders.

Reviews

“The intended audience is psychiatrists, pharmacologists, immunologists, counselors, toxicologists, social workers, addiction specialists, and all medical professionals working with patients with drug addictions. … This is the first book, and a most comprehensive one, about the research and development of biologics to treat substance use disorders and overdose. Hopefully, biologics will be part of the therapeutic armamentarium that healthcare providers can use in the treatment of their patients with these disorders.” (Michael Easton, Doody's Book Reviews, June, 2016)

Editors and Affiliations

  • National Institute on Drug Abuse, National Institutes of Health, Bethesda, USA

    Ivan D. Montoya

About the editor

Ivan D. MontoyaNational Institutes of Health, 
Bethesda, USA

Bibliographic Information

  • Book Title: Biologics to Treat Substance Use Disorders

  • Book Subtitle: Vaccines, Monoclonal Antibodies, and Enzymes

  • Editors: Ivan D. Montoya

  • DOI: https://doi.org/10.1007/978-3-319-23150-1

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing Switzerland 2016

  • Hardcover ISBN: 978-3-319-23149-5Published: 06 January 2016

  • Softcover ISBN: 978-3-319-79451-8Published: 30 March 2018

  • eBook ISBN: 978-3-319-23150-1Published: 18 December 2015

  • Edition Number: 1

  • Number of Pages: XVI, 453

  • Number of Illustrations: 47 b/w illustrations, 57 illustrations in colour

  • Topics: Psychopharmacology, Pharmacotherapy, Pharmacology/Toxicology

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access