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  • © 2016

Cancer of Unknown Primary

  • Explains the choice and role of different therapeutic options
  • Offers clear guidance on diagnosis of the tissue of origin
  • Describes how to identify patients with a more favorable prognosis

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-vi
  2. Introduction

    • Harald Löffler, Alwin Krämer
    Pages 1-4
  3. Biologic Features of CUP

    • Harald Löffler, Alwin Krämer
    Pages 27-44
  4. Prognostic Factors and Their Role in the Management of CUP

    • Harald Löffler, Alwin Krämer
    Pages 45-65
  5. The Radiologist’s Approach to CUP

    • Philipp M. Kazmierczak, Axel Rominger, Clemens C. Cyran
    Pages 75-90
  6. Cancer of Unknown Primary: The Pathologist’s Approach

    • Albrecht Stenzinger, Wilko Weichert
    Pages 91-112
  7. Treatment of Disseminated CUP

    • Gerdt Hübner
    Pages 113-123
  8. Concepts of Radiotherapy in Cancer of Unknown Primary

    • David Krug, Florian Sterzing
    Pages 125-149
  9. Favorable Subsets Among Cancers of Unknown Primary

    • Kanwal Raghav, Gauri R. Varadhachary
    Pages 151-172
  10. Future Directions

    • Alwin Krämer, Harald Löffler
    Pages 191-194

About this book

This book presents an up-to-date and thorough overview of cancer of unknown primary, encompassing topics ranging from epidemiology, tumor biology, and prognostic factors through to the most recent diagnostic and therapeutic advances. All aspects of management are covered, including radiological, nuclear medicine, and pathological diagnosis, site-specific therapies, platinum-based combination chemotherapy, radiotherapy, and novel targeted treatments. Clear guidance is offered on diagnosis of the tissue of origin by means of gene expression and micro-RNA analyses and its therapeutic implications. Detailed directions are also provided on the identification of subsets of patients with a more favorable prognosis, in whom specific treatment offers the chance of long-term survival or even cure. Readers will find Cancer of Unknown Primary to be an ideal source of practically oriented information that will assist in delivery of the best possible care for patients with this challenging diagnosis.

Editors and Affiliations

  • German Cancer Research Center (DKFZ) and University of Heidelberg, Clinical Cooperation Unit Molecular, Hematology/Oncology, Heidelberg, Germany

    Alwin Krämer, Harald Löffler

Bibliographic Information

  • Book Title: Cancer of Unknown Primary

  • Editors: Alwin Krämer, Harald Löffler

  • DOI: https://doi.org/10.1007/978-3-319-22581-4

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing Switzerland 2016

  • Hardcover ISBN: 978-3-319-22580-7Published: 03 November 2015

  • Softcover ISBN: 978-3-319-36458-2Published: 23 August 2016

  • eBook ISBN: 978-3-319-22581-4Published: 08 October 2015

  • Edition Number: 1

  • Number of Pages: VI, 194

  • Topics: Oncology, Diagnostic Radiology, Pathology

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 159.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access