Advances in Clinical Science

1. Front Matter

   Pages i-x

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2. Prevalence of Olfactory Impairment in Granulomatosis with Polyangiitis

   • K. Zycinska, M. Straburzynski, A. Nitsch-Osuch, R. Krupa, M. Hadzik-Błaszczyk, M. Cieplak et al.

   Pages 1-7

3. Biochemistry of Oxidative Stress

   • Michał P. Pruchniak, Magdalena Araźna, Urszula Demkow

   Pages 9-19

4. Usage of Over-the-Counter and Herbal Products in Common Cold in Poland: Findings from Consumer Survey

   • K. Karlowicz-Bodalska, K. Miśkiewicz, D. Kurpas, S. Han, A. Kowalczyk, D. Marciniak et al.

   Pages 21-27

5. RARβ Promoter Methylation as an Epigenetic Mechanism of Gene Silencing in Non-small Cell Lung Cancer

   • A. Dutkowska, A. Antczak, D. Pastuszak-Lewandoska, M. Migdalska-Sęk, K. H. Czarnecka, P. Górski et al.

   Pages 29-38

6. Cardiovascular Risk Factors in Obese Children and Adolescents

   • Małgorzata Rumińska, Anna Majcher, Beata Pyrżak, Aneta Czerwonogrodzka-Senczyna, Michał Brzewski, Urszula Demkow

   Pages 39-47

7. Nutrition and Immune System in Children with Simple Obesity

   • Aneta Czerwonogrodzka-Senczyna, Malgorzata Janusz, Anna Jeznach-Steinhagen, Urszula Demkow, Beata Pyrzak

   Pages 49-56

8. The Influence of Shockwave Therapy on Orthodontic Tooth Movement Induced in the Rat

   • Hagai Hazan-Molina, Itay Aizenbud, Hana Kaufman, Sorin Teich, Dror Aizenbud

   Pages 57-65

9. Thyroid Hormone Levels and TSH Activity in Patients with Obstructive Sleep Apnea Syndrome

   • P. Bielicki, T. Przybyłowski, M. Kumor, M. Barnaś, M. Wiercioch, R. Chazan

   Pages 67-71

10. Age and Gender-Related Changes in Biogenic Amine Metabolites in Cerebrospinal Fluid in Children

    • Katarzyna Kuśmierska, Krystyna Szymańska, Dariusz Rokicki, Katarzyna Kotulska, Sergiusz Jóźwiak, Jolanta Sykut-Cegielska et al.

    Pages 73-82

11. The Influence of Primary Cytomegalovirus or Epstein-Barr Virus Infection on the Course of Idiopathic Thrombocytopenic Purpura

    • Katarzyna Smalisz-Skrzypczyk, Michał Romiszewski, Michał Matysiak, Urszula Demkow, Katarzyna Pawelec

    Pages 83-88

12. Back Matter

    Pages 89-90

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The book presents the latest developments in clinical medicine, particularly involved with pulmonary care and diseases. Emphasis is placed on the role of childhood obesity, often a result of the ill effects of an unhealthy diet and nutritional deficits, in shaping propensity for inflammatory pathologies, allergies, immune deficiency and respiratory and cardiovascular sequelae in adult life. Oxidative damage, caused by not full well understood cellular biochemistry, when unchecked by antioxidative rescue mechanisms, takes toll on a respiratory health. The book underscores the need to consider the complexity of mutual interactions of pathophysiological processes, which calls for tailoring the management strategies depending on the subgroups which patients belong to, be it obesity, children or elderly. The chapters also tackle biological diseases with genetic underpinnings. The application of genetics to identify the molecular alterations or mutations will serve well both diagnostics and targeted optimization of treatment; the poignant exemplar being the histological subtypes of lung cancer. The book provides a source of current facts and trends in clinical research and practice.

• Immune system
• Lung Cancer
• Obesity
• Oxidative stress
• Respiratory infections

• Institute of Nursing, Public Higher Medical Professional School in Opole, Opole, Poland

  Mieczyslaw Pokorski

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