Malignant Pediatric Bone Tumors - Treatment & Management

1. Front Matter

   Pages i-xii

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2. Signs and Symptoms

   • Andrew A. Martin, Patrick J. Leavey

   Pages 1-7

3. Diagnostic Studies of Pediatric Bone Tumors: Pathology and Imaging

   • O. Hans Iwenofu, Stephen M. Druhan, Michael A. Arnold

   Pages 9-50

4. Basic Principles of Biopsy

   • Thomas J. Scharschmidt, Joel L. Mayerson

   Pages 51-56

5. The Evaluation of Lung Nodules in Pediatric Bone Tumors

   • Nicholas D. Yeager, Anthony N. Audino

   Pages 57-63

6. Fertility Preservation and Reproductive Health in Pediatric Bone Tumor Patients

   • Stacy L. Whiteside

   Pages 65-82

7. Chemotherapy Regimens for Patients with Newly Diagnosed Malignant Bone Tumors

   • Ryan D. Roberts, Mary Frances Wedekind, Bhuvana A. Setty

   Pages 83-107

8. Radiation Management

   • Ashley Sekhon, Karl Haglund, Michael Guiou

   Pages 109-124

9. Histological Response and Biological Markers

   • Kellie B. Haworth, Bhuvana A. Setty

   Pages 125-142

10. Surgical Approach: Limb Salvage Versus Amputation

    • Vincent Y. Ng, Thomas J. Scharschmidt

    Pages 143-154

11. Rehabilitation Following Orthopaedic Surgery in Children with Bone Tumors

    • Michelle A. Miller, Nathan Rosenberg

    Pages 155-169

12. Patient Navigation of the Pediatric Bone Tumor Patient Across the Continuum of Care

    • Paula M. Sanborn

    Pages 171-200

13. Psychosocial Effects of Pediatric Bone Tumors and Recommendations for Supportive Care

    • Cynthia A. Gerhardt, Amii C. Steele, Amanda L. Thompson, Tammi K. Young-Saleme

    Pages 201-210

14. Post-therapy Surveillance of Bone Tumors

    • Bhuvana A. Setty

    Pages 211-219

15. Recurrent Bone Tumors

    • Joanne Lagmay, Nicholas D. Yeager

    Pages 221-263

16. Novel Therapies on the Horizon

    • Timothy P. Cripe, Kellie B. Haworth, Peter J. Houghton

    Pages 265-291

17. Survivorship

    • Stacy L. Whiteside, Anthony N. Audino

    Pages 293-307

This book describes in detail current best practice in the diagnosis and treatment of malignant pediatric bone tumors and also discusses other important aspects of management. Clinical assessment, the role of different imaging modalities and choice of biopsy procedure are explained and an individual chapter is devoted to diagnostic pathology. The treatment-oriented chapters offer in-depth descriptions of chemotherapeutic regimens, radiation therapy, limb-salvage options and amputation-related issues and in addition consider the approach to lung nodules, the role of biomarkers, off-therapy monitoring and the treatment of relapse. Psychosocial impacts and needs are addressed and guidance provided on nursing during treatment and rehabilitation following orthopaedic surgery. Closing chapters evaluate emerging therapies and discuss disparate aspects of survivorship. The authors are acknowledged experts and include many contributors from the Nationwide Children’s Hospital, a leading pediatric care facility in the United States.

• Chemotherapy
• Ewing sarcoma
• Limb-salvage
• Osteosarcoma
• Survivorship

“The authors review in 16 chapters the symptoms, diagnosis and treatment (medical, chemo, radiation and surgical) of various malignant bone tumors. Several chapters are devoted to rehabilitation and post therapy surveillance. For pediatric oncologists.” (Pediatric Endocrinology Reviews (PER), Vol. 13 (3), March, 2016)

• Division of Pediatric Hematology/Oncology/Blood and Marrow Transplantation, Nationwide Children’s Hospital, Columbus, USA

  Timothy P. Cripe, Nicholas D. Yeager

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