Overview
- Editors:
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Stephen T. Sonis, DMD, DMSc
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Brigham and Women’s Hospital, Boston, USA
This book catalyzes the application of genomics to oral diseases by comprehensively presenting focused discussions on the current state of knowledge
Also focuses on gene-based therapies and pharmacogenomics application to oral diseases
Written by leaders in the field
Includes supplementary material: sn.pub/extras
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Table of contents (18 chapters)
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- J. Robert Chang, Enkhtsetseg Purev, Winston Patrick Kuo
Pages 11-34
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- Ingrid Glurich, Sanjay Shukla, Amit Acharya, Geoffrey S. Ginsburg, Murray H. Brilliant
Pages 35-65
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- Manuela Moraru, Carlos Vilches
Pages 67-90
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- Elizabeth J. Leslie, Mary L. Marazita
Pages 91-116
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- John R. Shaffer, Mary L. Marazita
Pages 117-144
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- Ricardo Carneiro Borra, Priscila Maria de Andrade
Pages 167-183
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- Nicola Luigi Bragazzi, Claudio Nicolini
Pages 185-217
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- Raman Mehrzad, Shawn Shetty, A. Razzaque Ahmed
Pages 219-251
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- Astrid Rasmussen, Christopher J. Lessard, Kathy L. Sivils
Pages 253-272
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- Chia-Cheng Li, Zhe Li, Reshma S Menon, Sook-Bin Woo
Pages 273-292
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- Srinivas Vinod Saladi, Leif W. Ellisen
Pages 293-309
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- Joel S. Greenberger, Michael W. Epperly, Peter Wipf, Song Li, Valerian Kagan, Xiang Gao
Pages 345-362
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- Kenneth S. Kornman, Gordon W. Duff, Kenneth Huttner, Peter J. Polverini, Jan Ching Chun Hu
Pages 363-388
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Back Matter
Pages 405-408
About this book
The objective of this book is to catalyze the application of genomics to the diagnosis and treatment of oral diseases by comprehensively presenting focused discussions on the current state of knowledge. The first section book provides basic information about genetics, genomics and personalized medicine and the informatical methods available to apply and organize genetic data so that it has clinical relevance. Recognizing the genetic robustness of the oral cavity, the introductory section includes chapters on the oral micro biome and host genomics and response to infectious agents. The next two sections contain chapters which describe the genomics of specific oral diseases and conditions, including the genetic basis for mechanism and risk of treatment toxicities associated with cancer therapy and bisphosphonates. Four chapters focus on gene-based therapies and the pharmacogenomics applied to oral disease. The final chapter presents a provocative summary which describes a comprehensive vision of the melding of genomics to personalized medicine and the potential actionable outcomes that will likely affect clinical practice in the upcoming years.
