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  • © 2017

Critical Care Toxicology

Diagnosis and Management of the Critically Poisoned Patient

  • Supports medical staff in the diagnosis, treatment and management of patients with acute poisoning

  • Updates the field with evidence-based paradigms and citations in each chapter

  • Collates the work of international experts on both toxic syndromes and posionings

  • Includes supplementary material: sn.pub/extras

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Table of contents (169 entries)

  1. Front Matter

    Pages i-xliii
  2. General Management of the Critically Poisoned Patient

    1. Front Matter

      Pages 1-1
    2. The Critically Poisoned Patient

      • J. Ward Donovan, Keith Burkhart, Jeffrey Brent
      Pages 3-27
    3. The Diagnostic Process in Medical Toxicology

      • Anthony F. Pizon, Joseph H. Yanta, Greg S. Swartzentruber
      Pages 29-41
    4. Post-Resuscitation Management of the Poisoned Patient

      • Michael Lynch, Jon C. Rittenberger
      Pages 101-115
    5. Psychiatric Issues in the Critically Poisoned Patient

      • J. J. Rasimas, Gregory L. Carter
      Pages 117-157
    6. Poisoning in Pregnancy

      • Kevin F. Maskell Jr., Kirk L. Cumpston, Timothy B. Erickson, Jerrold B. Leikin
      Pages 159-192
    7. Geriatric Poisoning

      • Janetta L. Iwanicki
      Pages 193-203
    8. Intensive Care of Pediatric Poisoning Cases

      • Prashant Joshi, Mitchell P. Ross
      Pages 205-222
    9. The Critically Poisoned Worker

      • Michael G. Holland
      Pages 223-248
    10. Extracorporeal Substance Removal

      • Monique J. Cormier, Marc Ghannoum
      Pages 267-278
    11. Poisoning Fatalities

      • Philippe E. Hantson
      Pages 279-292
  3. Toxic Syndromes

    1. Front Matter

      Pages 293-293
    2. Acid–Base Balance in the Poisoned Patient

      • Stephen W. Borron
      Pages 325-358
    3. Toxicant-Induced Hepatic Injury

      • Kim Dalhoff
      Pages 385-408

About this book

Building on the previous edition with contributions from internationally renowned experts this book provides a fully comprehensive resource for managing the post emergency/treatment stage of acute poisoning. Chapters incorporate evidence-based paradigms with up-to-date citations from the original medical literature. Topic areas covered include: diagnosis and management of the critically poisoned patient, including pediatric patients and poisoning in pregnancy; toxic syndromes including hepatotoxic and pulmonary syndromes as well as poisonings from medications, drugs of abuse, chemical and biological agents. This book is an essential resource for Clinical Toxicologists, Intensivists and Emergency Medicine specialists in training and in practice.

Reviews

“This is a valuable addition to the archives of clinical toxicology and will undoubtedly become the standard for the profession. … I highly recommend this book as a necessary addition to the professional library of every medical student and resident with an interest in clinical toxicology as well as practitioners at all levels (nurses, fellows, residents, and attending level physicians) of critical care, intensive care, emergency medicine, and clinical and medical toxicology.” (Michael I. Greenberg, Clinical Toxicology, Vol. 56 (3), December, 2017)

Editors and Affiliations

  • Department of Medicine, Division of Clinical Pharmacology and Toxicology, University of Colorado, School of Medicine, Aurora, USA

    Jeffrey Brent

  • FDA, Office of New Drugs/Immediate Office, Center for Drug Evaluation and Research, Silver Spring, USA

    Keith Burkhart

  • Clinical Toxicology, St Thomas’ Hospital, Silver Spring, USA

    Paul Dargan

  • Toxicology Associates, University of Colorado, School of Medicine, Denver, USA

    Benjamin Hatten, Robert Palmer

  • Medical Toxicological Intensive Care Unit, Lariboisiere Hospital, Paris-Diderot University, Paris, France

    Bruno Megarbane

  • Toxinology Department, Women’s and Children’s Hospital, North Adelaide, Australia

    Julian White

About the editors

Jeffrey Brent, M.D., Ph.D (biochemistry), is a Distinguished Clinical Professor of Medicine, University of Colorado School of Medicine and Colorado School of Public Health. He completed his medical toxicology Fellowship training at the Rocky Mountain Poison and Drug Center and has a long career of active research in medical toxicology. His Curriculum vitae lists nearly 300 publications of various kinds, including original research papers, abstracts, chapters, and reviews. Currently, Dr. Brent is Principal Investigator and Director of the Toxicology Investigators Consortium (ToxIC), an NIH supported national multi-center study group in medical toxicology.Dr. Brent is a former President of the American Academy of Clinical Toxicology (AACT), a former member of the Board of Directors of the American College of Medical Toxicology (ACMT), a recipient of the Louis Roche award from the European Association of Poisons Centres and Clinical Toxicologists, the Career Achievement Award from the AACT, and the Ellenhorn Award from the ACMT, and the Clinical Translational Sciences Career Achievement Award from the Society of Toxicology.

Dr Burkhart is the Lead Medical Officer for the Medical Informatics Team in the Division of Applied Regulatory Science in the Office of Clinical Pharmacology in the Office of Translational Sciences in the Center for Drug Evaluation and research at the FDA . He received his medical toxicology training at the Rocky Mountain Poison Center in Denver. Emergency medicine training was at the University of Cincinnati. His Medical Degree is from the Medical College of Pennsylvania, now Drexel University. His B.S. is from Ursinus College in Biology. He is a Past-President of the American College of Medical Toxicology. He is a Clinical Professor of Emergency Medicine at the Penn State University College of Medicine. Medical toxicology is practiced at the PinnacleHealth Hospital in Harrisburg, PA. He was the Medical Director for the Penn State Poison Center.


Dr Paul Dargan is a Consultant Physician and Clinical Toxicologist and Clinical Director at Guy's and St Thomas' NHS Foundation Trust, London, UK, and a Reader in Toxicology at King's College London. He has an active research and teaching programme with a focus on recreational drug toxicity, self-poisoning and heavy metal toxicity. He has published over 210 peer-reviewed papers and numerous book chapters. He sits on the UK Advisory Council on the Misuse of Drugs (ACMD), the Scientific Committee of the European Monitoring Centre for Drugs and Drugs Addiction EMCDDA) and is an expert adviser to a number of other bodies including the US Food and Drug Administration (FDA) and the World Health Organisation (WHO).

Dr. Hatten is an Assistant Professor of Emergency Medicine at the University of Colorado School of Medicine and Medical Toxicologist at the Rocky Mountain Poison and Drug Center in Denver, Colorado. He has an active toxicology practice in Denver and is academic faculty in the Medical Toxicology Fellowship and Emergency Medicine Residency at the University of Colorado.  In addition, he serves as an instructor in the Colorado School of Public Health. He underwent Medical Toxicology fellowship training and received a Master of Public Health at Oregon Health and Science University in Portland, Oregon. Prior to this, he completed Emergency Medicine residency training at Denver Health Medical Center in Denver, Colorado.  He is an alumni of the University of Texas-Southwestern School of Medicine in Dallas, Texas.  He also holds a Bachelor of Arts from Hendrix College in Conway, Arkansas. 

Bruno Megarbane is Professor of critical care medicine at Paris-Diderot University in Paris, France. He is the head of the Medical and Toxicological Intensive Care Unit, Lariboisière Hospital in Paris. His clinical researches focus at identifying prognostic factors and improving the management of severe poisonings including cardiotoxicant poisonings. He also actively participates to experimental researches at INSERM U1144, investigating the mechanisms of toxicity of psychotropic drugs like opioids and the new psychoactive substances. He is the President-elect of the European Association of Poison Centres and Clinical Toxicologists (EAPCCT). He is also an active member of the French Society of Intensive Care Medicine (SRLF), the European Society of Intensive Care Medicine (ESICM) and the American College of Medical Toxicology (ACMT). He is associate editor in Clinical Toxicology.

Dr. Palmer is a partner with the private practice Toxicology Associates in Denver, CO.  He completed a BS degree in chemistry at the University of Idaho, and MS and PhD degrees in organic-medicinal chemistry from the University of Washington.  He completed a NIDA postdoctoral fellowship at the University of Washington specializing in the pharmacology and medicinal chemistry of opioids, and a clinical toxicology fellowship at the Rocky Mountain Poison and Drug Center (RMPDC) in Denver, CO.  Dr. Palmer was previously faculty at the University of New Mexico Health Sciences Center, where he worked extensively with the Office of the Medical Investigator.  He is board-certified in clinical toxicology and currently president-elect of the American Academy of Clinical Toxicology.  He currently holds faculty appointments at the University of Wyoming, and University of Colorado School of Medicine, as well as serving as a faculty attending toxicologist for the medical toxicology fellowship program at the RMPDC.

Julian White AM; MB, BS, MD, FACTM is a consultant clinical toxinologist, founder and director of the Toxinology Department at Women’s & Children’s Hospital, Adelaide, Australia, Director of the Clinical Toxinology Short Courses, University of Adelaide. Internationally recognised for his contributions to clinical toxinology for more than 40 years, he has treated thousands of envenomed patients, authored hundreds of publications, and is Secretary/Treasurer of the International Society on Toxinology (IST) and Chair of the IST Board of Clinical Toxinology. He was awarded Membership of the Order of Australia (AM) for his contributions to clinical toxinology.

Bibliographic Information

  • Book Title: Critical Care Toxicology

  • Book Subtitle: Diagnosis and Management of the Critically Poisoned Patient

  • Editors: Jeffrey Brent, Keith Burkhart, Paul Dargan, Benjamin Hatten, Bruno Megarbane, Robert Palmer, Julian White

  • DOI: https://doi.org/10.1007/978-3-319-17900-1

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Reference Module Biomedical and Life Sciences

  • Copyright Information: Springer International Publishing AG 2017

  • License: CC BY

  • Hardcover ISBN: 978-3-319-17899-8Published: 24 July 2017

  • eBook ISBN: 978-3-319-17900-1Published: 23 June 2017

  • Edition Number: 2

  • Number of Pages: XLIII, 3058

  • Number of Illustrations: 381 b/w illustrations, 294 illustrations in colour

  • Topics: Pharmacology/Toxicology, Emergency Medicine, Intensive / Critical Care Medicine

Buy it now

Buying options

eBook USD 338.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 379.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access