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  • © 2015

Screening the Single Euploid Embryo

Molecular Genetics in Reproductive Medicine

Editors:

  • Provides explanation of each step of the process -- from ovulation induction to embryo transfer

  • Maximizes reader insights into the value of transferring a single embryo and explores ethical and regulatory issues in single embryo IVF transfer

  • Details and assesses the molecular techniques for embryo evaluation

  • Includes supplementary material: sn.pub/extras

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Table of contents (28 chapters)

  1. Front Matter

    Pages i-xi
  2. The Development of PGD

    • Joy D. A. Delhanty
    Pages 1-4
  3. Single Gamete Insemination Aiming at the Ideal Conceptus

    • Queenie V. Neri, Tyler Cozzubbo, Stephanie Cheung, Zev Rosenwaks, Gianpiero D. Palermo
    Pages 73-88
  4. Comprehensive Chromosomal Screening from Polar Body Biopsy to Blastocyst Trophectoderm Sampling: Evidences and Considerations

    • Antonio Capalbo, Danilo Cimadomo, Laura Rienzi, Filippo Maria Ubaldi
    Pages 89-102
  5. Polar Body Diagnosis (PBD): An Alternative and Supplement to Preimplantation Diagnosis for Single Embryo Transfer

    • Bruno Imthurn, Wolfgang Berger, Ervin Macas, István Magyar, Beatrice Oneda, Anita Rauch et al.
    Pages 103-121
  6. Prediction of Embryo Viability by Morphokinetic Evaluation to Facilitate Single Transfer

    • Aisling Ahlström, Alison Campbell, Hans Jakob Ingerslev, Kirstine Kirkegaard
    Pages 133-145
  7. Utilisation of Transcriptome-Based Biomarkers for Single Embryo Transfer

    • Rok Devjak, Tanja Burnik Papler, Eda Vrtacnik Bokal
    Pages 147-161
  8. Array CGH and Partial Genome Sequencing for Rapidly Karyotyping IVF Blastocysts Before Single Transfer

    • Paulette Barahona, Don Leigh, William Ritchie, Steven J. McArthur, Robert P. S. Jansen
    Pages 163-178
  9. SNP Array, qPCR, and Next-Generation Sequencing-Based Comprehensive Chromosome Screening

    • Nathan R. Treff, Eric J. Forman, Richard T. Scott Jr.
    Pages 193-202
  10. Expanding PGD Applications to Nontraditional Genetic and Non-genetic Conditions

    • Anver Kuliev, Svetlana Rechitsky, Oleg Verlinsky
    Pages 203-215
  11. Selecting the Right Embryo in Mitochondrial Disorders

    • Suzanne C. E. H. Sallevelt, Joseph C. F. M. Dreesen, Irenaeus F. M. de Coo, Christine E. M. de Die-Smulders, Hubert J. M. Smeets
    Pages 231-246
  12. Single Embryo Transfer: Significance of the Embryo Transfer Technique

    • Gautam N. Allahbadia, Rubina Merchant
    Pages 247-262

About this book

Intended for readers with a background in fertility medicine as well as those less familiar with IVF, this comprehensive work presents an update on preimplantation genetic testing to enable single embryo transfer (SET). An international cast of contributors explains the treatment sequence—from ovulation induction to luteal support—aiming to transfer only one euploid embryo. Applications of molecular techniques for gamete and embryo assessment are fully detailed, with a focus on the strengths and limitations of each. In addition, expert commentary is shared across a range of regulatory challenges associated with embryo screening and cryopreservation. As access to advanced reproductive technology increases against a sharper background of healthcare reform, clinicians, economists, bioethicists and legislators alike will find this new volume relevant and highly accessible.

Editors and Affiliations

  • Center for Advanced Genetics, Reproductive Research Section, Carlsbad, USA

    E Scott Sills

About the editor

Eric Scott Sills received his undergraduate degree from Vanderbilt and holds a PhD (molecular biology) from London’s University of Westminster. Dr. Sills was awarded the MD degree from University of Tennessee in 1992. After a gynecology residency at NYU Downtown Hospital, he completed his sub-specialty training in reproductive endocrinology at Cornell University. Having authored more than 100 peer-reviewed publications, Dr. Sills served as editor-in-chief for the Journal of Experimental & Clinical Assisted Reproduction from 2004–2014. He is board-certified by the American Board of Obstetrics and Gynecology, and is a Fellow of the American College of Obstetricians and Gynecologists, American College of Surgeons, Royal College of Physicians (Ireland), and Society of Biology (UK). At present, Dr. Sills is Medical Director at the Center for Advanced Genetics, an in vitro fertilization program based in Carlsbad, California. He is registered and/or licensed for medicine in California, New York and the United Kingdom.

Bibliographic Information

  • Book Title: Screening the Single Euploid Embryo

  • Book Subtitle: Molecular Genetics in Reproductive Medicine

  • Editors: E Scott Sills

  • DOI: https://doi.org/10.1007/978-3-319-16892-0

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing Switzerland 2015

  • Hardcover ISBN: 978-3-319-16891-3Published: 15 September 2015

  • Softcover ISBN: 978-3-319-35767-6Published: 22 October 2016

  • eBook ISBN: 978-3-319-16892-0Published: 07 September 2015

  • Edition Number: 1

  • Number of Pages: XI, 393

  • Number of Illustrations: 4 b/w illustrations, 34 illustrations in colour

  • Topics: Reproductive Medicine, Human Genetics, Embryology

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access