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Cell Polarity 1

Biological Role and Basic Mechanisms

  • Book
  • © 2015

Overview

Editors:
  1. Klaus Ebnet

    1. Institute-associated Research Group “Cell Adhesion and Cell Polarity”, Institute of Medical Biochemistry, Center for Molecular Biology of Inflammation (ZMBE), University Münster, Münster, Germany

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    You can also search for this editor in PubMed   Google Scholar

  • Explains the mechanism of cell polarity in an easily understandable and clear manner

  • Illustrates the physiological and pathophysiological relevance of cell polarity

  • Describes cell types, contexts and model organisms

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-viii
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  2. Cell Polarity Regulators: Conserved Sets of Cell Polarity Proteins as Molecular Toolkits

    1. Front Matter

      Pages 1-1
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    2. The PAR3-aPKC-PAR6 Complex

      • Shigeo Ohno, Spyros Goulas, Tomonori Hirose
      Pages 3-23

    3. PAR-1 Kinase and Cell Polarity

      • Atsushi Suzuki
      Pages 25-50

    4. The Crumbs3 Complex

      • Barbara Vacca, Magali Barthélémy-Requin, Céline Burcklé, Dominique Massey-Harroche, André Le Bivic
      Pages 51-63

    5. The Scribble–Dlg–Lgl Module in Cell Polarity Regulation

      • Patrick O. Humbert, Sarah M. Russell, Lorey Smith, Helena E. Richardson
      Pages 65-111

  3. Cell Polarity: Different Aspects and Basic Principles of Regulation

    1. Front Matter

      Pages 113-113
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    2. Front-to-Rear Polarity in Migrating Cells

      • Flora Llense, Sandrine Etienne-Manneville
      Pages 115-146

    3. Neuronal Polarity

      • Bhavin Shah, Alejandro Lopez Tobon, Andreas W. Püschel
      Pages 147-165

    4. Epithelial Apicobasal Polarity in the Drosophila Embryo

      • Tao Jiang, Daryl J. V. David, Tony J. C. Harris
      Pages 167-187

    5. The Polarized Distribution of the Na+,K+-ATPase

      • M. Cereijido, R. G. Contreras, M. I. Larre, L. Shoshani
      Pages 189-204

    6. Endothelial Cell Polarization During Lumen Formation, Tubulogenesis, and Vessel Maturation in 3D Extracellular Matrices

      • George E. Davis, Katherine R. Speichinger, Pieter R. Norden, Dae Joong Kim, Stephanie L. K. Bowers
      Pages 205-220

    7. Phosphoinositides as Determinants of Membrane Identity, Apicobasal Polarity, and Lumen Formation

      • Annette M. Shewan, Aline Awad, Juan Peng, Ama Gassama-Diagne
      Pages 221-244

  4. Cell Polarity and Cell–Cell Interactions: The Role of Cell Adhesion

    1. Front Matter

      Pages 245-245
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    2. Immunological Synapse Formation: Cell Polarity During T Cell–APC Interaction

      • Xin Liu, Morgan Huse
      Pages 247-275

    3. Homotypic Cell–Cell Interactions and Apicobasal Polarity in Epithelial Cells and Endothelial Cells

      • Benjamin Franz Brinkmann, Hüseyin Tuncay, Klaus Ebnet
      Pages 277-302

    4. Cell–Cell Interactions, Cell Polarity, and the Blood–Testis Barrier

      • Elizabeth I. Tang, Dolores D. Mruk, Will M. Lee, C. Yan Cheng
      Pages 303-326

  5. Protein Sorting and Distribution in Polarized Epithelial Cells

    1. Front Matter

      Pages 327-327
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    2. Membrane Traffic and Apicobasal Polarity in Drosophila Epithelial Cells

      • Barry J. Thompson
      Pages 329-348

    3. Roles of Rab Family Small G Proteins in Formation of the Apical Junctional Complex in Epithelial Cells

      • Ayuko Sakane, Takuya Sasaki
      Pages 349-374
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Keywords

About this book

This work provides a state-of-the art overview on the most relevant aspects of cell polarity.

Volume 1 addresses cell polarity and cell migration (front-rear polarity), cell polarity and barrier formation (apico-basal polarity) and neuronal polarity. It particularly focuses on cell polarity at the molecular level and the underlying molecular mechanisms. It also elaborates the common principles and mechanisms that regulate cellular polarization in different cell types and contexts.

Both volumes are intended for professors, group leaders and researchers in cell biology as well as medical professionals in the fields of anatomy, cell biology, physiology, pathology and tumor biology.

Editors and Affiliations

  • Institute-associated Research Group “Cell Adhesion and Cell Polarity”, Institute of Medical Biochemistry, Center for Molecular Biology of Inflammation (ZMBE), University Münster, Münster, Germany

    Klaus Ebnet

Bibliographic Information

  • Book Title: Cell Polarity 1

  • Book Subtitle: Biological Role and Basic Mechanisms

  • Editors: Klaus Ebnet

  • DOI: https://doi.org/10.1007/978-3-319-14463-4

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing Switzerland 2015

  • Hardcover ISBN: 978-3-319-14462-7Published: 25 March 2015

  • Softcover ISBN: 978-3-319-34507-9Published: 05 October 2016

  • eBook ISBN: 978-3-319-14463-4Published: 04 March 2015

  • Edition Number: 1

  • Number of Pages: VIII, 397

  • Number of Illustrations: 5 b/w illustrations, 57 illustrations in colour

  • Topics: Cell Physiology, Cancer Research, Human Physiology

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