Authors:
- Nominated as an outstanding Ph.D. thesis by the University of Cambridge, UK
- Offers a concise overview of holographic sensors and their fundamentals
- Presents comprehensive computational methods and experimental techniques
- Provides tutorials for fabricating holographic pH, organic solvent, metal ion, and glucose sensors
- Includes supplementary material: sn.pub/extras
Part of the book series: Springer Theses (Springer Theses)
Buy it now
Buying options
Tax calculation will be finalised at checkout
Other ways to access
This is a preview of subscription content, log in via an institution to check for access.
About this book
This thesis presents a theoretical and experimental approach for the rapid fabrication, optimization and testing of holographic sensors for the quantification of pH, organic solvents, metal cations, and glucose in solutions.
Developing non-invasive and reusable diagnostics sensors that can be easily manufactured will support the monitoring of high-risk individuals in any clinical or point-of-care setting. Sensor fabrication approaches outlined include silver-halide chemistry, laser ablation and photopolymerization. The sensors employ off-axis Bragg diffraction gratings of ordered silver nanoparticles and localized refractive index changes in poly (2-hydroxyethyl methacrylate) and polyacrylamide films. The sensors exhibited reversible Bragg peak shifts, and diffracted the spectrum of narrow-band light over the wavelength range λpeak ≈ 495-1100 nm. Clinical trials of glucose sensors in the urine samples of diabetic patients demonstrated that they offer superior performance compared to commercial high-throughput urinalysis devices. Lastly, a generic smartphone application to quantify colorimetric tests was developed and tested for both Android and iOS operating systems. The sensing platform and smartphone application may have implications for the development of low-cost, reusable and equipment-free point-of-care diagnostic devices.
Authors and Affiliations
-
Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom
Ali Kemal Yetisen
About the author
Bibliographic Information
Book Title: Holographic Sensors
Authors: Ali Kemal Yetisen
Series Title: Springer Theses
DOI: https://doi.org/10.1007/978-3-319-13584-7
Publisher: Springer Cham
eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)
Copyright Information: Springer International Publishing Switzerland 2015
Hardcover ISBN: 978-3-319-13583-0Published: 18 December 2014
Softcover ISBN: 978-3-319-36722-4Published: 10 September 2016
eBook ISBN: 978-3-319-13584-7Published: 03 December 2014
Series ISSN: 2190-5053
Series E-ISSN: 2190-5061
Edition Number: 1
Number of Pages: XVIII, 162
Number of Illustrations: 17 b/w illustrations, 55 illustrations in colour
Topics: Industrial Chemistry/Chemical Engineering, Medicinal Chemistry, Laboratory Medicine