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Molecular Therapies of Cancer

  • Book
  • © 2015

Overview

Authors:
  1. Georg F. Weber

    1. University of Cincinnati College of Pharmacy, Cincinnati, USA

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  • Provides a comprehensive treatise on anti-cancer drugs

  • Covers all aspects of molecular cancer drugs, including medicincal chemistry, pharmacology, and signal transduction Includes sections on anti-metastasis therapy and combination chemotherapy?

  • Explores emerging and alternative treatment modalities

  • Includes supplementary material: sn.pub/extras

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Table of contents (19 chapters)

  1. Front Matter

    Pages i-xv
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  2. General Principles

    1. Front Matter

      Pages 1-1
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    2. Principles of Molecular Cancer Treatment

      • Georg F. Weber
      Pages 3-5

  3. Molecular Basis of Anti-Cancer Drug Treatment

    1. Front Matter

      Pages 7-7
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    2. DNA Damaging Drugs

      • Georg F. Weber
      Pages 9-112

    3. Drugs that Suppress Proliferation

      • Georg F. Weber
      Pages 113-162

    4. Molecular Inhibitors of Growth Signals

      • Georg F. Weber
      Pages 163-242

    5. Anti-Metastasis Therapy

      • Georg F. Weber
      Pages 243-259

    6. Induction of Senescence

      • Georg F. Weber
      Pages 261-262

    7. Combination Chemotherapy

      • Georg F. Weber
      Pages 263-279

  4. Emerging and Alternative Treatment Modalities

    1. Front Matter

      Pages 281-281
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    2. Gene Therapy

      • Georg F. Weber
      Pages 283-296

    3. Drugs with Diverse Modes of Action

      • Georg F. Weber
      Pages 297-300

  5. Molecular Targeting of Tumor-Host Interactions

    1. Front Matter

      Pages 301-301
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    2. Hormone Therapy

      • Georg F. Weber
      Pages 303-332

    3. Immunotherapy

      • Georg F. Weber
      Pages 333-351

    4. Anti-Angiogenesis

      • Georg F. Weber
      Pages 353-371

  6. Anti-Cancer Drug Pharmacokinetics

    1. Front Matter

      Pages 373-373
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    2. Drug Delivery and Drug Transport

      • Georg F. Weber
      Pages 375-387

    3. Drug Metabolism

      • Georg F. Weber
      Pages 389-393
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Keywords

About this book

Molecular Therapies of Cancer comprehensively covers the molecular mechanisms of anti-cancer drug actions in a comparably systematic fashion. While there is currently available a great deal of literature on anti-cancer drugs, books on the subject are often concoctions of invited review articles superficially connected to one another. There is a lack of comprehensive and systematic text on the topic of molecular therapies in cancer. A further deficit in the relevant literature is a progressive sub-specialization that typically limits textbooks on cancer drugs to cover either pharmacology or medicinal chemistry or signal transduction, rather than explaining molecular drug actions across all those areas; Molecular Therapies of Cancer fills this void. The book is divided into five sections: 1. Molecular Targeting of Cancer Cells; 2. Emerging and Alternative Treatment Modalities; 3. Molecular Targeting of Tumor-Host Interactions; 4. Anti-Cancer Drug Pharmacokinetics; and 5. Supportive Therapies.

Authors and Affiliations

  • University of Cincinnati College of Pharmacy, Cincinnati, USA

    Georg F. Weber

About the author

Georg Weber, MD, PhD, is Associate Professor at the James L. Winkle College of Pharmacy at the University of Cincinnati. Dr. Weber has made contributions to metastasis research by discovering the interaction between the molecules osteopontin and CD44 and by defining the physiologic role of metastasis genes as stress response genes. While he continues to address fundamental questions, he is researching new venues for diagnosis and therapy of cancer progression. Dr. Weber's professional affiliations include the American Association for the Advancement of Science, American Medical Association, American Association for Cancer Research, and Metastasis Research Society. Dr. Weber has published several books including Molecular Mechanisms of Cancer, which was published by Springer.

Bibliographic Information

  • Book Title: Molecular Therapies of Cancer

  • Authors: Georg F. Weber

  • DOI: https://doi.org/10.1007/978-3-319-13278-5

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing Switzerland 2015

  • Hardcover ISBN: 978-3-319-13277-8Published: 03 August 2015

  • Softcover ISBN: 978-3-319-35212-1Published: 15 October 2016

  • eBook ISBN: 978-3-319-13278-5Published: 22 July 2015

  • Edition Number: 1

  • Number of Pages: XV, 488

  • Number of Illustrations: 34 b/w illustrations, 86 illustrations in colour

  • Topics: Cancer Research, Laboratory Medicine, Oncology

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