Overview
Highlights each RTK family and the multiple receptors within each family
Discusses each receptor’s family in development and human disease
Analyses each family’s receptors, receptor processing and signal attenuation
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Table of contents (19 chapters)
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Front Matter
Keywords
About this book
Reviews
“An in depth study of the RTK families in 19 chapters. … Clearly written and with extensive references after each chapter. For endocrinologists, molecular biologists and oncologists.” (Pediatric Endocrinology Reviews (PER), Vol. 13 (3), March, 2016)
Editors and Affiliations
About the editors
Dr. Deric Wheeler received an M.S. in pathology from the University of Iowa and a Ph.D. in Cancer Biology from the University of Wisconsin. He conducted his postdoctoral training at the Fred Hutchinson Cancer Research Center in Seattle, WA, and at the University of Wisconsin School of Medicine and Public Health in Madison, where he eventually transitioned to faculty as an assistant professor in the department of human oncology. Dr. Wheeler’s lab research centers on resistance to molecular targeting agents and the role of subcellular localization of receptor tyrosine kinases and their roles in oncogenesis.
Dr. Yosef Yarden received a Ph.D. in Molecular Biology from the Weizmann Institute of Science in Rehovot, Israel. He completed postdoctoral training at Genentech, Inc. in San Francisco and at the Massachusetts Institute of Technology in Cambridge. He returned to the Weizmann Institute of Science first as an assistant professor and then later as a full professor. His past administrative responsibilities at the Weizmann Institute include Dean of the Faculty of Biology, Vice-President for Academic Affairs, Director of the M.D. Moross Institute for Cancer Research, and Dean of the Feinberg Graduate School. Dr. Yarden’s lab research centers on the roles played by growth factors and receptor tyrosine kinases in tumor progression.
Bibliographic Information
Book Title: Receptor Tyrosine Kinases: Family and Subfamilies
Editors: Deric L. Wheeler, Yosef Yarden
DOI: https://doi.org/10.1007/978-3-319-11888-8
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing Switzerland 2015
Hardcover ISBN: 978-3-319-11887-1Published: 13 August 2015
Softcover ISBN: 978-3-319-35397-5Published: 22 October 2016
eBook ISBN: 978-3-319-11888-8Published: 31 July 2015
Edition Number: 1
Number of Pages: XVII, 878
Number of Illustrations: 21 b/w illustrations, 79 illustrations in colour
Topics: Cell Biology, Receptors, Pharmaceutical Sciences/Technology