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Inflammatory Disorders

  • Book
  • © 2015

Overview

Editors:
  1. Mieczyslaw Pokorski

    1. Institute of Psychology, Opole University, Poland

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  • A quick guide through allergy and sensitization
  • Translation of science into clinical practice
  • Presentation of innovative markers of oxidative stress
  • Includes supplementary material: sn.pub/extras

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 839)

Part of the book sub series: Neuroscience and Respiration (NR)

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Table of contents (9 chapters)

  1. Front Matter

    Pages i-x
    Download chapter PDF

  2. Inhaled Corticosteroids Increase Siglec-5/14 Expression in Sputum Cells of COPD Patients

    • P. Wielgat, R. M. Mroz, A. Stasiak-Barmuta, P. Szepiel, E. Chyczewska, J. J. Braszko et al.
    Pages 1-5

  3. Tregs and HLA-DR Expression in Sputum Cells of COPD Patients Treated with Tiotropium and Formoterol

    • A. Holownia, P. Wielgat, A. Stasiak-Barmuta, A. Kwolek, P. Jakubow, P. Szepiel et al.
    Pages 7-12

  4. Inhalation of Macrolides: A Novel Approach to Treatment of Pulmonary Infections

    • R. Siekmeier, T. Hofmann, G. Scheuch
    Pages 13-24

  5. Influence of Denture Plaque Biofilm on Oral Mucosal Membrane in Patients with Chronic Obstructive Pulmonary Disease

    • D. Przybyłowska, E. Mierzwińska-Nastalska, R. Rubinsztajn, R. Chazan, D. Rolski, E. Swoboda-Kopeć
    Pages 25-30

  6. Biophysical Activity of Animal-Derived Exogenous Surfactants Mixed with Rifampicin

    • M. Kolomaznik, A. Calkovska, E. Herting, G. Stichtenoth
    Pages 31-39

  7. Organic Changes in the Central Nervous System in Children on Chronic Inhaled Corticosteroid Therapy

    • M. Michalczuk, A. J. Sybilski, A. Piliszek, J. Walecki
    Pages 41-45

  8. Stem Cell Experiments Moves into Clinic: New Hope for Children with Bronchopulmonary Dysplasia

    • K. Pawelec, D. Gładysz, U. Demkow, D. Boruczkowski
    Pages 47-53

  9. Soluble Ligand CD40 and Uric Acid as Markers of Atheromatosis in Patients with Obstructive Sleep Apnea

    • M. Kosacka, A. Brzecka, P. Piesiak, A. Korzeniewska, R. Jankowska
    Pages 55-60

  10. Carotid Artery Intima-Media Thickness in Hypertensive Patients with Obstructive Sleep Apnea

    • M. Kostrzewska, T. Piorunek, K. Hoffmann, H. Batura-Gabryel, S. Cofta
    Pages 61-66

  11. Back Matter

    Pages 67-67
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Keywords

About this book

The mechanistic basis of chronic inflammation remains unclear. The research sheds new light on the immune cells expressing the activation markers HLA-DR and regulatory T cells (Tregs) and the cells expressing Siglec receptors as being key players in the immune system responsiveness to antigens and thus in lung tissue damage of chronic inflammation. The results help understand the mechanisms of action of common drugs used in COPD, such as formoterol, tiotropium, or corticosteroids, and point to novel drug targets. The chapters also deal with brain damaging effects, by far unrecognized, of inhaled corticosteroid therapy, a time-proven management of chronic inflammatory airway conditions; asthma being a case in point. Novel methods, likely less producing side effects, of macrolide antibiotics administration by inhalation are discussed, emphasizing not only bacteriostatic but also anti-inflammatory action.

Editors and Affiliations

  • Institute of Psychology, Opole University, Poland

    Mieczyslaw Pokorski

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