Ras Superfamily Small G Proteins: Biology and Mechanisms 2

1. Front Matter

   Pages i-vi

   PDF

2. Rab Subfamily

   1. Front Matter

      Pages 1-1

      PDF

   2. Prenylation of RabGTPases, Their Delivery to Membranes, and Rab Recycling

      • Roger S. Goody, Yaowen Wu, Aymelt Itzen

      Pages 3-16

   3. Rab Proteins and the Organization of Organelle Membrane Domains

      • Marnix Wieffer, Marisa P. McShane, Marino Zerial

      Pages 17-38

   4. Effectors of Rab GTPases: Rab Binding Specificity and Their Role in Coordination of Rab Function and Localization

      • Lena Katharina Oesterlin, Olena Pylypenko, Bruno Goud

      Pages 39-66

   5. A Rab Effector Called the Exocyst and Related Vesicle Tether Complexes

      • Peter Jay Novick

      Pages 67-79

   6. Rab GEFs and GAPs: The Enigma Variations

      • Francis A. Barr

      Pages 81-106

3. Ran

   1. Front Matter

      Pages 107-107

      PDF

   2. Ran in Nucleocytoplasmic Transport

      • Murray Stewart

      Pages 109-124

   3. Ran in Mitosis

      • Oliver J. Gruss

      Pages 125-148

4. Arf Subfamily

   1. Front Matter

      Pages 149-149

      PDF

   2. Arf Proteins and Their Regulators: At the Interface Between Membrane Lipids and the Protein Trafficking Machinery

      • Catherine L. Jackson

      Pages 151-180

   3. Small G Proteins: Arf Family GTPases in Vesicular Transport

      • Frank Adolf, Felix T. Wieland

      Pages 181-214

   4. ARF-Like (ARL) Proteins

      • Richard A. Kahn, Michael P. East, Joshua W. Francis

      Pages 215-251

   5. ArfGAPs: Not Only for the Termination

      • Shigeru Hashimoto, Ari Hashimoto, Hirokazu Sugino, Ayumu Yoshikawa, Haruka Handa, Masanao Yoshino et al.

      Pages 253-274

5. RAGs

   1. Front Matter

      Pages 275-275

      PDF

   2. Rag GTPases

      • Jenna L. Jewell, Kun-Liang Guan

      Pages 277-292

6. Back Matter

   Pages 293-298

   PDF

This second of two volumes discusses subfamily proteins which function in molecular and vesicular transport mechanisms inside the cell. In this volume the focus lies on the Rab, Ran and Arf subfamily members. As in Volume 1, the book is written by international renowned scientists in the field of small G-proteins. In elaborate reviews, biochemistry, structure, function and G-protein - effector interactions are described. Together with Volume 1 this book provides an comprehensive state-of-the-art work on small G-proteins (GTPases). It is written for Graduates and Professors in Biochemistry and Cell Biology interested in the mechanism and function of small G-proteins but are extremely valuable for those who want to move into the field.

• G-Protein effector-interactions
• GTP binding
• GTPase
• intracellular transport
• nucleo-cytoplasmic transport
• vesicular coats
• Protein Structure

• Max-Planck-Institute of Molecular Physiology, Dortmund, Germany

  Alfred Wittinghofer

Policies and ethics