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  • © 2014

Mathematical Cardiac Electrophysiology

  • State-of-the-art modeling in the fast-growing field of computational electrocardiology
  • Rigorous presentation of the mathematical foundations and numerical treatment of current cardiac models
  • Up-to-date coverage of the relevant research projects and literature
  • Includes supplementary material: sn.pub/extras

Part of the book series: MS&A (MS&A, volume 13)

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Table of contents (9 chapters)

  1. Front Matter

    Pages i-xiv
  2. Basic Cardiac Anatomy and Electrocardiology

    • Piero Colli Franzone, Luca F. Pavarino, Simone Scacchi
    Pages 1-19
  3. Mathematical Models of Cellular Bioelectrical Activity

    • Piero Colli Franzone, Luca F. Pavarino, Simone Scacchi
    Pages 21-75
  4. Mathematical Models of Cardiac Cells Arrangements: The Bidomain Model

    • Piero Colli Franzone, Luca F. Pavarino, Simone Scacchi
    Pages 77-122
  5. Reduced Macroscopic Models: The Monodomain and Eikonal Models

    • Piero Colli Franzone, Luca F. Pavarino, Simone Scacchi
    Pages 123-148
  6. Anisotropic Cardiac Sources

    • Piero Colli Franzone, Luca F. Pavarino, Simone Scacchi
    Pages 149-173
  7. The Inverse Problem of Electrocardiology

    • Piero Colli Franzone, Luca F. Pavarino, Simone Scacchi
    Pages 175-190
  8. Numerical Methods for the Bidomain and Reduced Models

    • Piero Colli Franzone, Luca F. Pavarino, Simone Scacchi
    Pages 191-206
  9. Parallel Solvers for the Bidomain System

    • Piero Colli Franzone, Luca F. Pavarino, Simone Scacchi
    Pages 207-248
  10. Simulation Studies of Cardiac Bioelectrical Activity

    • Piero Colli Franzone, Luca F. Pavarino, Simone Scacchi
    Pages 249-360
  11. Back Matter

    Pages 361-400

About this book

This book covers the main mathematical and numerical models in computational electrocardiology, ranging from microscopic membrane models of cardiac ionic channels to macroscopic bidomain, monodomain, eikonal models and cardiac source representations. These advanced multiscale and nonlinear models describe the cardiac bioelectrical activity from the cell level to the body surface and are employed in both the direct and inverse problems of electrocardiology. The book also covers advanced numerical techniques needed to efficiently carry out large-scale cardiac simulations, including time and space discretizations, decoupling and operator splitting techniques, parallel finite element solvers. These techniques are employed in 3D cardiac simulations illustrating the excitation mechanisms, the anisotropic effects on excitation and repolarization wavefronts, the morphology of electrograms in normal and pathological tissue and some reentry phenomena. The overall aim of the book is to present rigorously the mathematical and numerical foundations of computational electrocardiology, illustrating the current research developments in this fast-growing field lying at the intersection of mathematical physiology, bioengineering and computational biomedicine. This book is addressed to graduate student and researchers in the field of applied mathematics, scientific computing, bioengineering, electrophysiology and cardiology.

Reviews

“This book aims to present recent mathematical and numerical advances in cardiac electrophysiology, in a comprehensive manner and with a special emphasis on large-scale numerical simulations. … the presentation is as clear as possible, which makes the book a valuable resource for graduate students and researchers in electrophysiology and cardiology, not only for the amount and quality of the material reviewed, but also for the quality of the presentation.” (Paul Georgescu, zbMATH 1318.92002, 2015)

Authors and Affiliations

  • Dipartimento di Matematica, Università degli Studi di Pavia, Pavia, Italy

    Piero Colli Franzone

  • Dipartimento di Matematica, Università degli Studi di Milano, Milano, Italy

    Luca Franco Pavarino, Simone Scacchi

Bibliographic Information

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access