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  • © 2014

Mechanisms of Atrial Arrhythmias

Insights from the Development of a Biophysically Detailed Model of the Human Atria

Authors:

  • Nominated as an outstanding Ph.D. thesis by the University of Manchester, UK
  • Elucidates the mechanisms underlying atrial fibrillation
  • May assist in the prevention and treatment of atrial fibrillation
  • Provides detailed, multi-scale model of the heterogeneous human atria and torso
  • Provides models of anatomically accurate and electrophysiologically detailed pacemaker structures
  • Includes supplementary material: sn.pub/extras

Part of the book series: Springer Theses (Springer Theses)

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Table of contents (9 chapters)

  1. Front Matter

    Pages i-xxii
  2. Introduction

    • Michael A. Colman
    Pages 1-7
  3. Background

    • Michael A. Colman
    Pages 9-55
  4. Single Cell Modelling of the Human Atria

    1. Front Matter

      Pages 57-57
    2. Development of a Family of Regional Cell Models

      • Michael A. Colman
      Pages 87-114
  5. 3-D Modelling of the Human Atria

    1. Front Matter

      Pages 157-157
    2. 3D Anatomical Modelling of the Atria

      • Michael A. Colman
      Pages 159-184
    3. Atrial Fibrillation

      • Michael A. Colman
      Pages 201-225
    4. Discussion

      • Michael A. Colman
      Pages 227-247
  6. Back Matter

    Pages 249-256

About this book

This thesis describes the development of biophysically detailed computer models of the human atria and torso to study the underlying mechanisms of cardiac diseases, some of the most common causes of morbidity and mortality. This is a cross-disciplinary project, involving fundamentals of cardiac electrophysiology, physics of excitable media, applied mathematics and high performance scientific computing and visualisation. The author uses computer models to provide insights into the underlying mechanisms of the genesis of atrial fibrillation and develops novel techniques for the monitoring of atrial tachycardia.

Authors and Affiliations

  • School of Physics and Astronomy, University of Manchester, Manchester, United Kingdom

    Michael A. Colman

Bibliographic Information

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access