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Progressive Supranuclear Palsy: Diagnosis, Pathology, and Therapy

  • Conference proceedings
  • © 1994

Overview

Editors:
  1. E. Tolosa

    1. Neurology Service, Hospital Clinic, Faculty of Medicine, University of Barcelona, Spain

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  2. R. Duvoisin

    1. Neurology Service, Robert Wood Johnson University Hospital, New Brunswick, USA

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  3. F. F. Cruz-Sánchez

    1. Neurological Tissue Bank, Faculty of Medicine, University of Barcelona, Spain

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Journal of Neural Transmission. Supplementa (NEURAL SUPPL, volume 42)

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Table of contents (22 papers)

  1. Front Matter

    Pages I-X
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  2. Clinical aspects

    1. Front Matter

      Pages 1-1
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    2. Historical notes

      • John C. Steele
      Pages 3-14

    3. Clinical diagnosis and diagnostic criteria of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome)

      • E. Tolosa, F. Valldeoriola, M. J. Marti
      Pages 15-31

    4. Eyelid motor abnormalities in progressive supranuclear palsy

      • F. Grandas, A. Esteban
      Pages 33-41

    5. The auditory startle response in progressive supranuclear palsy

      • J. C. Rothwell, M. Vidailhet, P. D. Thompson, A. J. Lees, C. D. Marsden
      Pages 43-50

    6. Differential diagnosis of PSP

      • R. C. Duvoisin
      Pages 51-67

    7. Cognitive disturbances in progressive supranuclear palsy

      • I. Litvan
      Pages 69-78

    8. Progressive supranuclear palsy and corticobasal ganglionic degeneration: differentiation by clinical features and neuroimaging techniques

      • S. Giménez-Roldán, D. Mateo, C. Benito, F. Grandas, Y. Pérez-Gilabert
      Pages 79-90

  3. Neuroimage analysis, cerebral blood flow and metabolism

    1. Front Matter

      Pages 91-91
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    2. Magnetic resonance imaging in progressive supranuclear palsy and other parkinsonian disorders

      • M. Savoiardo, F. Girotti, L. Strada, E. Ciceri
      Pages 93-110

    3. Clinical progressive supranuclear palsy: differential diagnosis by IBZM-SPECT and MRI

      • G. Arnold, K. Tatsch, W. H. Oertel, Th. Vogl, J. Schwarz, E. Kraft et al.
      Pages 111-118

    4. PET studies in progressive supranuclear palsy

      • D. J. Brooks
      Pages 119-134

  4. Morphological aspects

    1. Front Matter

      Pages 135-135
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    2. The neuropathology of progressive supranuclear palsy

      • P. L. Lantos
      Pages 137-152

    3. Neurofibrillary pathology in progressive supranuclear palsy (PSP)

      • J. Cervós-Navarro, K. Schumacher
      Pages 153-164

    4. Antigenic determinant properties of neurofibrillary tangles Relevance to progressive supranuclear palsy

      • F. F. Cruz-Sánchez
      Pages 165-178

    5. Cortical tangles in progressive supranuclear palsy

      • M. Verny, C. Duyckaerts, P. Delaère, Y. He, J.-J. Hauw
      Pages 179-188

    6. Vascular progressive supranuclear palsy

      • J. Winikates, J. Jankovic
      Pages 189-201

  5. Biochemical aspects

    1. Front Matter

      Pages 203-203
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Keywords

About this book

When Steele, Richardson and Olszewski described Progressive Supranuclear Palsy in Archives of Neurology in 1964, it was thought to be a rare disease. Recent pathological studies of large numbers of patients diagnosed as having Parkinson's disease in life have highlighted the fact that at least one in ten of such cases have some other condition. Progressive Supranuclear Palsy is one of the commonest alternative diagnoses. This book is therefore a timely review of present understanding of Progressive Supranuclear Palsy. Much has been learnt about this sporadic illness of middle and late life although its cause remains unknown, and its treatment continues to be difficult. The Editors have selected a team of authors who review the clinical aspects, neuro-imaging find­ ings, neuropathology, neurochemistry, epidemiology, and therapy of Progres­ sive Supranuclear Palsy. All are to congratulated on producing an excellent and detailed picture of contemporary knowledge of the condition. Anyone interested in Progressive Supranuclear Palsy cannot do better than to start by reading this book. It is to be hoped that it will prompt further investigation to establish its cause and cure. C. D. MARSDEN, London Preface Progressive Supranuclear Palsy (PSP) is a neurodegenerative disorder charac­ terized clinically by the appearance of a supranuclear gaze palsy and extra­ pyramidal features which include bradykinesia and axial dystonia. Postural instability and falls and frontal-type behavioural and cognitive disturbances complete the clinical picture of this progressive disorder.

Editors and Affiliations

  • Neurology Service, Hospital Clinic, Faculty of Medicine, University of Barcelona, Spain

    E. Tolosa

  • Neurology Service, Robert Wood Johnson University Hospital, New Brunswick, USA

    R. Duvoisin

  • Neurological Tissue Bank, Faculty of Medicine, University of Barcelona, Spain

    F. F. Cruz-Sánchez

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