Progress in Drug Research

1. Front Matter

   Pages 1-7

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2. Nicotine: An addictive substance or a therapeutic agent?

   • David M. Warburton

   Pages 9-41

3. Aspirin as an antithrombotic agent

   • Melvin J. Silver, Giovanni di Minno

   Pages 43-62

4. The mode of action of anti-rheumatic drugs. 1. Anti-inflammatory and immunosuppressive effects of glucocorticoids

   • Anthony C. Allison, Simon W. Lee

   Pages 63-81

5. The use of neutrophils, macrophages and organ cultures to assess the penetration of human cells by antimicrobials

   • Zell A. McGee, Gary L. Gorby, Wanda S. Updike

   Pages 83-92

6. RNA virus evolution and the control of viral disease

   • Esteban Domingo

   Pages 93-133

7. Medicinal agents incorporating the 1,2-diamine functionality

   • Erik T. Michalson, Jacob Szmuszkovicz

   Pages 135-149

8. Adrenergic receptor research: Recent developments

   • George Kunos

   Pages 151-167

9. From podophyllotoxin glucoside to etoposide

   • H. Stähelin, A. von Wartburg

   Pages 169-266

10. Emerging concepts towards the development of contraceptive agents

    • Ranjan P. Srivastava, A. P. Bhaduri

    Pages 267-315

11. Chemotherapy for systemic mycoses

    • Paul D. Hoeprich

    Pages 317-351

12. Effects of drugs on calmodulin-mediated enzymatic actions

    • Judit Ovádi

    Pages 353-395

13. The significance of DNA technology in medicine

    • Hansjakob Müller

    Pages 397-413

14. Immunotherapy for leprosy and tuberculosis

    • J. L. Stanford

    Pages 415-448

15. Back Matter

    Pages 449-501

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In the first years of the existence of this series of monographs, during the so-called "Golden Age" of drug research, the majority of the pa­ pers published were mainly concerned with the traditional domains of drug research, namely chemistry, pharmacology, toxicology and pre­ clinical investigations. The series' aim was to give coverage to impor­ tant areas of research, to introduce new active substances with thera­ peutic potential and to call attention to unsolved problems. This objective has not changed. The table of contents of the present volume makes evident, however, that the search for new medicines has become increasingly complex, and additional, new disciplines have entered the research arena. The series now includes reviews on bio­ chemical, biological, immunological, physiological and medicinal aspects of drug research. Researchers actively engaged in the various scientific fields forming the entity of drug research can benefit from the wealth of knowledge and experience of the respective authors, and will be assisted in their endeavour to discover new pharmaceutical agents. Those simply wanting to keep abreast of new developments in the complex, multi-discipline science can turn to the "Progress in Drug Research" volumes as an almost encyclopaedic source of information without having to consult the innumerable original publications. Volume 33 contains 13 reviews, a subject index, an index for the close to 400 articles published in the series so far, and an author and titles index for all 33 volumes.

• RNA
• chemistry
• chemotherapy
• drug
• drug research
• evolution
• immunotherapy
• medicine
• research
• science
• technology

• Basel, Switzerland

  Ernst Jucker

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