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Nitric Oxide in Pulmonary Processes

Role in Physiology and Pathophysiology of Lung Disease

  • Book
  • © 2000

Overview

Editors:
  1. Maria G. Belvisi

    1. Pharmacology Department, Rhône-Poulenc Rorer Research & Development, Dagenham, Essex, UK

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    You can also search for this editor in PubMed   Google Scholar

  2. Jane A. Mitchell

    1. Unit of Critical Care Medicine Imperial College Medical School, Royal Brompton Hospital, London, UK

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Respiratory Pharmacology and Pharmacotherapy (RPP)

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Table of contents (12 chapters)

  1. Front Matter

    Pages I-IX
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  2. Introduction to Nitric Oxide Biology

    1. Front Matter

      Pages 1-1
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    2. Nitric Oxide Synthesis and Actions

      • David Bishop-Bailey, Jane A. Mitchell
      Pages 3-20

    3. Reactive Oxygen and Reactive Nitrogen Species in the Lung

      • Gregory J. Quinlan, Nicholas J. Lamb
      Pages 21-38

  3. Role of Endogenous Nitric Oxide in the Lung

    1. Front Matter

      Pages 39-39
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    2. Non-Adrenergic Non-Cholinergic Neurotransmission in the Airways: Role of Nitric Oxide

      • Maria G. Belvisi, Alan Gibson
      Pages 41-70

    3. Localisation of Nitric Oxide Synthases in the Lung

      • Axel Fischer
      Pages 71-88

    4. Role of Nitric Oxide in the Regulation of Pulmonary Vascular Tone

      • Shu F. Liu, Timothy W. Evans
      Pages 89-110

    5. Nitric Oxide and Bronchial Hyperresponsiveness

      • Frans P. Nijkamp, Gert Folkerts
      Pages 111-126

    6. Bronchodilator Actions of Nitric Oxide and Related Compounds

      • Sanjay Mehta, Jeffrey M. Drazen
      Pages 127-149

    7. Role of Nitric Oxide in Airway Inflammation

      • El-Bdaoui Haddad
      Pages 151-164

  4. Therapeutic Potential of Inhaled Nitric Oxide and Nitric Oxide Synthase Inhibitors in Lung Disease

    1. Front Matter

      Pages 165-165
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    2. Nitric Oxide in Exhaled Air: Relevance in Inflammatory Lung Disease

      • Peter J. Barnes, Sergei A. Kharitonov
      Pages 167-183

    3. Luminal Nitric Oxide in the Upper Airways: Implications for Local and Distal Sites of Action

      • Kjell Alving, Jon O. N. Lundberg, Johan Rinder, Eddie Weitzberg
      Pages 185-199

    4. Inhaled Nitric Oxide as a Therapy for Diseases of the Pulmonary Vasculature

      • Helen M. Marriott, Timothy W. Higenbottam
      Pages 201-208

    5. Combined Use of Nitric Oxide and Nitric Oxide Synthase Inhibitors as a Possible Therapeutic Approach

      • Christoph Thiemermann
      Pages 209-225

  5. Back Matter

    Pages 227-230
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Keywords

About this book

Nitric oxide is an endogenously produced gas with a wide range of biological effects and has been implicated in many physiological and pathophysiological processes. It is released by many cell types in various organs but is particularly important in the maintenance of normal lung function. Nitric oxide in exhaled breath has been identified as a marker for lung disease in some patients. Thus, it is appropriate to consider the lung separately for the role and functioning of nitric oxide. The authors identify key areas in the history, biochemistry, physiology, pathophysiology, immunology and clinical applications of nitric oxide in the lung. The contents of this book will be of particular importance to scientists and clinicians with an interest in lung disease. Moreover, the authors encompass state of the art opinions of and rational for the therapeutic potential of nitric oxide and its inhibitors.

Editors and Affiliations

  • Pharmacology Department, Rhône-Poulenc Rorer Research & Development, Dagenham, Essex, UK

    Maria G. Belvisi

  • Unit of Critical Care Medicine Imperial College Medical School, Royal Brompton Hospital, London, UK

    Jane A. Mitchell

Bibliographic Information

  • Book Title: Nitric Oxide in Pulmonary Processes

  • Book Subtitle: Role in Physiology and Pathophysiology of Lung Disease

  • Editors: Maria G. Belvisi, Jane A. Mitchell

  • Series Title: Respiratory Pharmacology and Pharmacotherapy

  • DOI: https://doi.org/10.1007/978-3-0348-8474-7

  • Publisher: Birkhäuser Basel

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Basel AG 2000

  • Hardcover ISBN: 978-3-7643-5718-4Published: 10 November 1999

  • Softcover ISBN: 978-3-0348-9582-8Published: 23 October 2012

  • eBook ISBN: 978-3-0348-8474-7Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: IX, 230

  • Topics: Pharmacy

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