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Birkhäuser

Inflammatory Processes:

Molecular Mechanisms and Therapeutic Opportunities

  • Conference proceedings
  • © 2000

Overview

Editors:
  1. L. Gordon Letts

    1. NitroMed Inc., Bedford, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Douglas W. Morgan

    1. Abbott Laboratories, Abbott Park, USA

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Progress in Inflammation Research (PIR)

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Table of contents (17 papers)

  1. Front Matter

    Pages i-xi
    Download chapter PDF

  2. The role of eotaxin and related CC-chemokines in asthma and allergy

    1. The role of eotaxin and related CC-chemokines in asthma and allergy

      • Tracey J. Mitchell, Timothy J. Williams
      Pages 1-12

  3. Signal transduction by the JNK group of MAP kinases

    1. Signal transduction by the JNK group of MAP kinases

      • Roger J. Davis
      Pages 13-21

  4. Cellular signaling to NF-ĐşB: Role in inflammation and therapeutic promise

    1. Cellular signaling to NF-ĐşB: Role in inflammation and therapeutic promise

      • Marie Chabot-Fletcher
      Pages 23-37

  5. Small molecule regulators of AP-1 and NF-ĐşB

    1. Small molecule regulators of AP-1 and NF-ĐşB

      • Anthony M. Manning
      Pages 39-51

  6. Mammalian target of rapamycin: Immunosuppressive drugs offer new insights into cell growth regulation

    1. Mammalian target of rapamycin: Immunosuppressive drugs offer new insights into cell growth regulation

      • Robert T. Abraham
      Pages 53-66

  7. Constitutive expression of a tumor suppressor leads to tumor regression in a xenograft model

    1. Constitutive expression of a tumor suppressor leads to tumor regression in a xenograft model

      • Catherine Adams Burton, John Boylan, Candy Robinson, Janet Kerr, Pamela Benfield
      Pages 67-76

  8. Macrophage metalloproteinases in destructive inflammatory diseases

    1. Macrophage metalloproteinases in destructive inflammatory diseases

      • Steven D. Shapiro
      Pages 77-81

  9. Lymphotoxin in inflammation and lymphoid organ development: Variations on a theme

    1. Lymphotoxin in inflammation and lymphoid organ development: Variations on a theme

      • Nancy H. Ruddle
      Pages 83-88

  10. Chemokine/cytokine biology during the evolution of fibrotic disease

    1. Chemokine/cytokine biology during the evolution of fibrotic disease

      • Steven L. Kunkel, Sem H. Phan, Nicholas W. Lukacs, Cory Hogaboam, Stephen W. Chensue
      Pages 89-98

  11. The role of MCP-1 in disease

    1. The role of MCP-1 in disease

      • Long Gu, Susan C. Tseng, Barrett J. Rollins
      Pages 99-107

  12. The role of chemokines in allergic diseases of the airways

    1. The role of chemokines in allergic diseases of the airways

      • Lisa A. Beck, Cristiana Stellato, Syed Shahabuddin, Renate Nickel, Robert P. Schleimer
      Pages 109-118

  13. Ninth International Conference of the Inflammation Research Association, November 1-5, 1998: Summaries of workshops and poster discussions

    1. Front Matter

      Pages 119-119
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    2. Targets in rheumatoid and osteoarthritis

      • Willam Williams, Elizabeth Arner
      Pages 121-123

    3. Signal transduction and regulation of gene expression

      • Lawrence Wennogle, Nancy Cusack
      Pages 125-128

    4. Mediators of inflammation and their enzymes

      • James Burke, Floyd Chilton
      Pages 129-130

    5. Cell adhesion molecules and leukocyte trafficking

      • Denis Schrier, Fandrew Issekutz
      Pages 131-133

    6. Pulmonary inflammation, fibrosis, and disease

      • Robert M. Strieter, David Underwood
      Pages 135-137

    7. Angiogenesis, wound repair and skin inflammation

      • W. Hunter, E. Turley
      Pages 139-140

  14. Back Matter

    Pages 141-144
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Keywords

About this book

In November 1998 many of the key leaders of new drug discovery for inflammatory diseases gathered at Hershey, Pennsylvania for the 9th International Conference of the Inflammation Research Association. The Conference was held over a five day period and provided a stimulating environment for the open exchange of important advances in basic inflammation research as well as new drug discovery and development. This book encompasses some of the highlights of several presentations made at the Conference. It contains some of the latest and important developments in the field of inflammation research. Topics include the status of eotaxin and chemokines in asthma and allergy, signal transduction and regulation of diverse mediators such as the JNK group of MAP kinases, TNF and IL-1 signaling of NF-kB as well as regulators of AP-1, macrophage metalloproteinases, lymphotoxin and further insights into the role of MCP-1 in disease. Also discussed are drug targets in rheumatoid and osteoarthritis, fibrotic diseases,...

Editors and Affiliations

  • NitroMed Inc., Bedford, USA

    L. Gordon Letts

  • Abbott Laboratories, Abbott Park, USA

    Douglas W. Morgan

Bibliographic Information

  • Book Title: Inflammatory Processes:

  • Book Subtitle: Molecular Mechanisms and Therapeutic Opportunities

  • Editors: L. Gordon Letts, Douglas W. Morgan

  • Series Title: Progress in Inflammation Research

  • DOI: https://doi.org/10.1007/978-3-0348-8468-6

  • Publisher: Birkhäuser Basel

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Basel AG 2000

  • Hardcover ISBN: 978-3-7643-6025-2Published: 01 September 2000

  • Softcover ISBN: 978-3-0348-9580-4Published: 29 October 2012

  • eBook ISBN: 978-3-0348-8468-6Published: 06 December 2012

  • Series ISSN: 1422-7746

  • Series E-ISSN: 2296-4525

  • Edition Number: 1

  • Number of Pages: XI, 144

  • Topics: Immunology, Molecular Medicine, Pharmacology/Toxicology, Allergology

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